Immune System News and Research

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Modifier gene offers a likely explanation for less infection in some patients with cystic fibrosis

Cystic fibrosis is caused by an inherited mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

10 Dec 2019

ERC promotes CRISPR research to better treat infections

Chase Beisel heads the "Synthetic Biology of RNA" research group at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg, a branch of the Helmholtz Centre for Infection Research in Braunschweig and run in collaboration with the Julius-Maximilians-Universität in Würzburg.

10 Dec 2019

UA physician-scientist to study how common stressors affect the aging process

The human body gets stressed every single day. Whether we contract a minor infection or even argue with a loved one, these small stressors impact our immune system.

10 Dec 2019

Influenza IMPRINT Cohort study awarded $9.1 million boost from Open Philanthropy Project

A $30 million Influenza IMPRINT Cohort study led by Cincinnati Children's has been awarded a $9.1 million boost from the Open Philanthropy Project.

10 Dec 2019

New study uncovers the genetic basis of memory

New research has uncovered the genetic basis for different functions of memory.

10 Dec 2019

Common antibiotic appears to boost the effect of radiation on tumor cells

The antibiotic vancomycin alters the gut microbiome in a way that can help prime the immune system to more effectively attack tumor cells after radiation therapy.

9 Dec 2019

'Achilles' heel' of deadly superbug identified

A deadly superbug that infects an estimated 54,500 Americans a year has a secret weapon, a protein, that allows it to defy antibiotic treatment and immune system attacks.

9 Dec 2019

Stem cell transplant following treatment with PD-1 inhibitor is safe, effective for patients with Hodgkin lymphoma

A new analysis shows that a donor stem cell transplant following treatment with an immune checkpoint inhibitor is generally safe and produces good outcomes for patients with Hodgkin lymphoma, easing concerns that these patients are at heightened risk for severe immune-related complications.

9 Dec 2019

Small, thin metal mesh loaded with T cells shrinks tumors in ovarian cancer models

New findings published Dec. 9 in Nature Biomedical Engineering from scientists at Fred Hutchinson Cancer Research Center show for the first time that a piece of small, thin metal mesh loaded with cancer-fighting immune cells shrinks tumors in preclinical models of ovarian cancer.

9 Dec 2019

Some phages employ new strategy to avoid becoming the next casualty of DNA-dicing enzymes

Bacteria and the viruses that infect them are engaged in a molecular arms race as ancient as life itself. Evolution has equipped bacteria with an arsenal of immune enzymes, including CRISPR-Cas systems, that target and destroy viral DNA. But bacteria-killing viruses, also known as phages, have devised their own tools to help them outmaneuver even the most formidable of these bacterial defenses.

9 Dec 2019

Study shows how a new combination approach helps overcome resistance to cancer immunotherapy

Cancer immunology drugs, which harness the body's immune system to better attack cancer cells, have significantly changed the face of cancer treatment. People with aggressive cancers are now living longer, healthier lives. Unfortunately, cancer immunology therapy only works in a subset of patients.

9 Dec 2019

Research shows how high levels of blood fat induce inflammation and organ damage

Viral and bacterial infections are not the only causes of inflammation of body tissue. It has been known for some time that certain fat molecules in our bloodstream can also trigger an inflammatory response.

9 Dec 2019

NTU scientists find potential route to disabling viruses causing severe respiratory diseases

A team of molecular and structural biologists from Nanyang Technological University, Singapore have found a potential new route to disabling respiratory syncytial virus and human metapneumovirus after elucidating the structure of one of its key components.

9 Dec 2019

New approach to broadly acting, highly effective HIV vaccine

Researchers have reported a major advance in the creation of a successful HIV vaccine that is not produced by the host animal.

9 Dec 2019

Piglet study shows probiotics and prebiotics work differently in girls and boys

The team from the Universities of Bristol and Reading found that 28-day old piglets produced very different levels of immune cells, antibodies and other immune-associated molecules depending on their sex, contradicting previous evidence suggesting that the difference in immunity begins during puberty.

9 Dec 2019

Nanosize container can slip inside cells and deliver medicines, gene therapies

Scientists at Johns Hopkins Medicine report they have created a tiny, nanosize container that can slip inside cells and deliver protein-based medicines and gene therapies of any size - even hefty ones attached to the gene-editing tool called CRISPR.

6 Dec 2019

Pilot clinical trial tests new treatment for type 1 diabetes

Type 1 diabetes is a chronic condition in which the body's own immune system attacks and destroys beta cells in the pancreas. Once the beta cells are destroyed, the pancreas can no longer produce insulin. Currently, there is no cure for T1D and treatment focuses on managing blood sugar levels.

6 Dec 2019

Researchers identify a missed opportunity in the treatment of ER+ breast cancers

In the United States, apart from some forms of skin cancer, breast cancer is the most common cancer in women. It is also the most common cause of death from cancer among Hispanic women and the second most common among all other women, after lung cancer.

6 Dec 2019

Breakthrough research develops novel vaccine poised to cure peanut allergies

Peanut allergies could become a thing of the past as breakthrough research from the University of South Australia develops a radically novel vaccination that's poised to cure the potentially life threatening condition.

6 Dec 2019

Genetically engineered living hydrogel material facilitates intestinal wound healing

About 1.6 million people in the US alone currently have lifelong and incurable Inflammatory Bowel Disease (IBD) including Crohn's disease and ulcerative colitis, and 70,000 new cases are diagnosed in the USA each year.

6 Dec 2019

Immune System News and Research

Modifier gene offers a likely explanation for less infection in some patients with cystic fibrosis

ERC promotes CRISPR research to better treat infections

UA physician-scientist to study how common stressors affect the aging process

Influenza IMPRINT Cohort study awarded $9.1 million boost from Open Philanthropy Project

New study uncovers the genetic basis of memory

Common antibiotic appears to boost the effect of radiation on tumor cells

'Achilles' heel' of deadly superbug identified

Stem cell transplant following treatment with PD-1 inhibitor is safe, effective for patients with Hodgkin lymphoma

Small, thin metal mesh loaded with T cells shrinks tumors in ovarian cancer models

Some phages employ new strategy to avoid becoming the next casualty of DNA-dicing enzymes

Study shows how a new combination approach helps overcome resistance to cancer immunotherapy

Research shows how high levels of blood fat induce inflammation and organ damage

NTU scientists find potential route to disabling viruses causing severe respiratory diseases

New approach to broadly acting, highly effective HIV vaccine

Piglet study shows probiotics and prebiotics work differently in girls and boys

Nanosize container can slip inside cells and deliver medicines, gene therapies

Pilot clinical trial tests new treatment for type 1 diabetes

Researchers identify a missed opportunity in the treatment of ER+ breast cancers

Breakthrough research develops novel vaccine poised to cure peanut allergies

Genetically engineered living hydrogel material facilitates intestinal wound healing

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