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Study raises questions about drug regulators' independence

Patients and doctors expect drug regulators to provide an unbiased, rigorous assessment of new medicines before they hit the market.

30 Jun 2022

Proteins in the eye may predict which macular degeneration patients need life-long treatment

In a study of eye fluid from 38 patients, Johns Hopkins Medicine researchers say they have found that levels of a specific protein appears to help accurately predict whether people with the wet form of age-related macular degeneration may need lifelong, frequent eye injections to preserve vision or if they can be safely weaned off the treatments.

29 Jun 2022

Anticancer drug candidate that targets a human protein could be a pan-viral medication

More than two years into the COVID-19 pandemic, people are realizing that the "new normal" will probably involve learning to co-exist with SARS-CoV-2. Some treatments are available, but with new variants emerging, researchers are looking toward new strategies.

29 Jun 2022

Researchers explore disease severity post-infection with SARS-CoV-2 Omicron in hematologic patients

A new study has studied the clinical outcome and spectrum in 61 patients infected with the SARS-CoV-2 Omicron variant.

29 Jun 2022

Immune particles from llama blood could offer protection against several COVID-19 variants

Mount Sinai-led researchers have shown that tiny, robust immune particles derived from the blood of a llama could provide strong protection against every COVID-19 variant, including Omicron, and 18 similar viruses including SARS-CoV-2 and SARS-CoV-1, which was responsible for the 2003 SARS outbreak.

29 Jun 2022

Complex molecular dance could inform the development of future treatments for fragile X syndrome

Like many neurological diseases, there's a lot we don't understand about fragile X syndrome. But, after studying the disorder for several years, Lynne Maquat's lab knew two important things: the enzyme AKT, which plays a key role in cell growth and survival, and the quality control pathway known as NMD (nonsense-mediated mRNA decay), are both in overdrive in fragile X.

29 Jun 2022

Investigating the prerequisites for developing RNA-based antibiotics

In the fight against the Covid-19 pandemic, mRNA-based vaccines have impressively demonstrated their potential. Using this technology, scientists were able to rapidly develop and bring to market vaccines against SARS-CoV-2 that have been extremely effective at protecting millions of people against severe disease progression of COVID-19 or even death.

29 Jun 2022

New study looks at the role of beta cells in triggering autoimmunity

Research into the causes of type 1 diabetes often focuses on the autoimmune response, where the immune system destroys pancreatic islet beta cells that produce insulin.

28 Jun 2022

BNT162b2 COVID vaccine stimulates significant antibody response in lung cancer patients

In a recent article posted to the medRxiv* preprint server, scientists from Japan assessed the safety and immunogenicity of coronavirus disease 2019 (COVID-19) BNT162b2 vaccine among lung cancer patients under treatment.

28 Jun 2022

UC enrolling patients for clinical trial of novel PTSD treatments

About 8% of Americans will experience post-traumatic stress disorder at some point in their lives, but there are still few effective options to treat the condition.

28 Jun 2022

$Simple X-ray method could help prevent spinal fractures in older people$

Simple X-ray method could help prevent spinal fractures in older people

Among older people, vertebral compression fractures are very common, and those with such fractures are at high risk of incurring new ones. Findings in a new thesis from the University of Gothenburg indicate that a simple X-ray method should be introduced as a routine procedure in Swedish health care.

28 Jun 2022

Researchers assess the evidence basis for medications used to treat spine-related pain in older adults

Spine-related pain is increasingly common in older adults. While medications play an important role in pain management, their use has limitations in geriatric patients due to reduced liver and kidney function, comorbid medical problems and polypharmacy (the simultaneous use of multiple drugs to treat medical conditions).

28 Jun 2022

Study uncovers a new, specific target for developing treatments for cocaine addiction

Researchers have found that blocking certain acetylcholine receptors in the lateral habenula (LHb), an area of the brain that balances reward and aversion, made it harder to resist seeking cocaine in a rat model of impulsive behavior.

28 Jun 2022

New machine learning method may improve the identification of genes that cause diseases

A new machine learning method to model gene expression levels might improve the identification of genes that cause human diseases, according to a new study by Penn State College of Medicine researchers.

28 Jun 2022

Study identifies critical genes and biological pathways related to COVID-19 myocarditis

Scientists from China have recently deciphered the genetic network and biological mechanisms associated with COVID-19 myocarditis using bioinformatic methods.

28 Jun 2022

SARS-CoV-2 virus undertakes a massive takeover of the body's fat-processing system

The virus that causes COVID-19 undertakes a massive takeover of the body's fat-processing system, creating cellular storehouses of fat that empower the virus to hijack the body's molecular machinery and cause disease.

28 Jun 2022

Antiretroviral drug used to treat HIV ameliorates cognitive deficits in mouse model of Down syndrome

Lamivudine, a commonly-used antiretroviral drug for treating HIV, improves cognition in a mouse model of Down syndrome, according to the findings of a joint new study by researchers at the Centre for Genomic Regulation (CRG) and the IrsiCaixa AIDS Research Institute, a center jointly promoted by the "la Caixa" Foundation and the Department of Health of the Generalitat de Catalunya.

28 Jun 2022

Drugs News and Research

Study raises questions about drug regulators' independence

Proteins in the eye may predict which macular degeneration patients need life-long treatment

Anticancer drug candidate that targets a human protein could be a pan-viral medication

Researchers explore disease severity post-infection with SARS-CoV-2 Omicron in hematologic patients

Immune particles from llama blood could offer protection against several COVID-19 variants

Complex molecular dance could inform the development of future treatments for fragile X syndrome

Investigating the prerequisites for developing RNA-based antibiotics

New study looks at the role of beta cells in triggering autoimmunity

BNT162b2 COVID vaccine stimulates significant antibody response in lung cancer patients

UC enrolling patients for clinical trial of novel PTSD treatments

Simple X-ray method could help prevent spinal fractures in older people

Researchers assess the evidence basis for medications used to treat spine-related pain in older adults

Study uncovers a new, specific target for developing treatments for cocaine addiction

New machine learning method may improve the identification of genes that cause diseases

Study identifies critical genes and biological pathways related to COVID-19 myocarditis

SARS-CoV-2 virus undertakes a massive takeover of the body's fat-processing system

Antiretroviral drug used to treat HIV ameliorates cognitive deficits in mouse model of Down syndrome

Study elucidates the molecular mechanisms of acetylcholine for learning and memory

Study reveals surprising reasons why cancer cells are often forced to rely on fat imports

Sanford Burnham Prebys scientist receives NIH grant to continue research on cellular signaling in cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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