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Guardian molecule found to prevent cancer cells from changing identity

A guardian molecule ensures that liver cells do not lose their identity. This has been discovered by researchers from the German Cancer Research Center (DKFZ), the Hector Institute für Translational Brain Research (HITBR), and from the European Molecular Biology Laboratory (EMBL).

13 Feb 2025

Study identifies novel enhancers linked to neuropsychiatric disorders

Neuropsychiatric disorders are becoming increasingly prevalent. Given their complex and multifactorial pathogenesis, there is an urgent need for effective and targeted therapies that can improve patients' quality of life.

13 Feb 2025

Research shows early childcare boosts development in toddlers

For about 60 years, the prevailing wisdom in Japan, so-called "Three-Year-Old Myth," has held that children should be raised at home by their mothers until the age of three for healthy development.

13 Feb 2025

Epidural steroid injections may offer modest short-term pain relief for some back pain

The American Academy of Neurology (AAN) has developed a new systematic review to summarize for neurologists and other clinicians the evidence for epidural steroid injections and whether they reduce pain and disability for people with certain kinds of chronic back pain.

13 Feb 2025

Hybrid closed-loop insulin pumps improve time in range, but increase ketoacidosis

People with type 1 diabetes require continuous insulin treatment and must regularly measure their glucose levels. With open-loop therapies*, insulin administration is manually controlled, while hybrid closed-loop systems* automatically regulate insulin delivery.

13 Feb 2025

Olpasiran significantly lowers "bad cholesterol" linked to cardiovascular risk

The RNA inhibitor olpasiran significantly reduces a type of "bad cholesterol" that's associated with a high risk of cardiovascular events, according to results from an analysis by a Mount Sinai researcher of a phase 2 trial.

13 Feb 2025

Systemic racism may play a role in genetic testing disparities, study suggests

For children with signs of neurological conditions such as autism, epilepsy and global developmental delay, genetic testing can help make the diagnosis, identify possible treatments and determine whether family members could be affected, among other benefits.

13 Feb 2025

PAC-MANN blood test could help detect pancreatic cancer at early stages

A new blood test could help doctors detect pancreatic cancer earlier, potentially improving survival rates for one of the deadliest cancers.

12 Feb 2025

Study uncovers how MAGE-4 and Pten loss promote aggressive tumor growth

A study published in Science Advances reveals a novel strategy that allows tumors to evade the body's immune response critical for their elimination.

12 Feb 2025

Type 1 diabetes patients face lower cardiovascular risk than Type 2 diabetes

A new study published in JSCAI has revealed a lower risk of cardiovascular events for patients with Type 1 diabetes (often called juvenile diabetes) compared to those with Type 2 diabetes.

12 Feb 2025

Study identifies vitamin E succinate as key to tumor growth control

High levels of fat mass and obesity-associated protein (FTO) have been linked to increased tumor growth and resistance to immunotherapy.

12 Feb 2025

McMaster University researchers discover new blood clotting disorder

Researchers at McMaster University have made a groundbreaking discovery in the field of hematology, providing an explanation for spontaneous and unusual blood-clotting that continues to occur despite treatment with full-dose blood thinners.

12 Feb 2025

New research advances understanding of Parkinson's disease stages

From a study that analyzed brain images of more than 2,500 people with Parkinson's disease in 20 different countries, scientists were able to identify patterns of neurodegeneration and create metrics for each of the five clinical stages of the disease.

12 Feb 2025

Blood test can predict preterm preeclampsia with 80% accuracy

A new blood test has an 80% accuracy in predicting preterm preeclampsia, according to a study published today, Feb. 12, in the journal Nature Medicine.

12 Feb 2025

Diabetes plays key role in the emergence and expansion of antibiotic resistance

Antibiotics are powerful, fast-acting medications designed to eradicate bacterial infections. However, in recent years, their dependability has waned as antibiotic resistant bacteria continues to evolve and spread.

12 Feb 2025

Blockbuster drug for diabetes and obesity could also help reduce alcohol intake

The blockbuster drug semaglutide, better known as Ozempic for diabetes and Wegovy for obesity, could also help people cut down on their alcohol intake, according to new USC research.

12 Feb 2025

Telehealth shows promise for substance use disorder treatment in rural areas

Recognition of telehealth as an effective strategy for delivering treatment for substance use disorder (SUD) has raised hopes for improving access to this treatment in settings with limited transportation or when time constraints compromise regular use of consistent access to in-person substance use treatment.

12 Feb 2025

New discovery could overcome immune therapy failure in ovarian cancer

University of Virginia Cancer Center researchers have explained the failure of immune checkpoint therapy for ovarian cancer by discovering how gut bacteria interfere with the treatment.

12 Feb 2025

Groundbreaking malaria vaccine provides high-level protection with just one dose

Scientists at Sanaria and Seattle Children's Research Institute's Center for Global Infectious Disease Research (CGIDR) have unveiled a groundbreaking malaria vaccine, Sanaria® PfSPZ-LARC2 Vaccine, designed to provide high-level protection with just one dose.

12 Feb 2025

University of Michigan tests novel mechanical heart pump in clinical trial

A cardiac surgery and heart failure team at the University of Michigan implanted a novel mechanical heart pump into a patient as part of a clinical trial that will compare it to the only device currently used to treat end-stage heart failure.

12 Feb 2025