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OptiNose presents sumatriptan Phase II trial results at 2nd European Headache and Migraine Trust International

OptiNose Inc. announced the results from an analysis comparing the Phase II clinical trial obtained with its novel delivery technology to that of other formulations. The analysis suggests rapid absorption rate alone may not explain the efficacy in migraines treated with sumatriptan delivered with the Company's novel bi-directional technology. The results will be presented at the 2nd European Headache and Migraine Trust International on 28th of October 2010.

30 Oct 2010

Eating disorders negatively affect oral health

While the connection between oral health and systemic health has been well-established, what most people don't know is that dentists often are in a position to detect systemic conditions. According to an article published in the October 2010 issue of AGD Impact, the monthly newsmagazine of the Academy of General Dentistry (AGD), dentists may be the first health care providers to notice evidence of an eating disorder, such as anorexia nervosa, bulimia nervosa, binge eating disorder, and pica.

29 Oct 2010

Pfizer announces approval of Lyrica capsules for peripheral neuropathic pain

Pfizer Inc announced that the Japanese Ministry of Health, Labour and Welfare approved Lyrica (pregabalin) capsules for the treatment of peripheral neuropathic pain. This follows the recent approval in Japan of Lyrica for the treatment of postherpetic neuralgia on April 16, 2010. Lyrica is the first medication approved for peripheral neuropathic pain in Japan where it is co-promoted with Eisai Co., Ltd.

29 Oct 2010

New computer program shows how brain's complex fiber tracks mature as we grow up

The brain's inner network becomes increasingly more efficient as humans mature. Now, for the first time without invasive measures, a joint study from the Ecole Polytechnique F-d-rale de Lausanne (EPFL) and the University of Lausanne (UNIL), in collaboration with Harvard Medical School, has verified these gains with a powerful new computer program. Reported in the PNAS early online edition last week, the soon-to-be-released software allows for individualized maps of vital brain connectivity that could aide in epilepsy and schizophrenia research.

28 Oct 2010

NICE issues PTNS guidance for overactive bladder

Uroplasty, Inc. announced today that the United Kingdom's National Institute for Health and Clinical Excellence (NICE) issued a guidance document titled "Percutaneous Posterior Tibial Nerve Stimulation for Overactive Bladder Syndrome," reinforcing the safety and effectiveness of PTNS for overactive bladder.

28 Oct 2010

Monitoring glucose levels in brain can help predict second-wave of damage in head injury patients

Why do some of the one million people who sustain head injuries annually in United States experience a mysterious second wave of brain damage days after the initial injury - just when they appear to be recovering? Limited clinical trials using an innovative new device to monitor brain chemistry on a second-by-second basis are underway to answer that life-and-death question, according to an article in the current issue of Chemical & Engineering News (C&EN), ACS' weekly newsmagazine. Brain injury is the leading cause of death and disability worldwide.

28 Oct 2010

Researchers develop software tool to study wiring of brains

A team of researchers at the Eindhoven University of Technology has developed a software tool that physicians can use to easily study the wiring of the brains of their patients. The tool converts MRI scans using special techniques to three-dimensional images. This now makes it possible to view a total picture of the winding roads and their contacts without having to operate.

28 Oct 2010

Causes, prevention, and management of inferior alveolar nerve injury during implant dentistry

Although implant dentistry has become widely accepted to restore esthetics and function of teeth, it is not without risks. One serious complication that can occur is alteration of sensation due to nerve injury. Some reports place this occurrence as high as 13%. For dental practitioners, thorough understanding of anatomy, surgical procedures, and implant systems along with proper planning of treatment are essential to reduce this complication.

28 Oct 2010

Advanced procedure for microsurgical breast reconstruction offered at Baptist Health hospitals

When pediatrician Julie A. Buckley, MD, learned that she had breast cancer last year, she chose breast reconstruction using the “DIEP flap” procedure. DIEP (Deep Inferior Epigastric Artery Perforator) flap is available mainly at regional academic centers in the United States.

27 Oct 2010

Diabetes threatens the eyesight of many unsuspecting Americans

Diabetes causes more new cases of legal blindness among working-age Americans than any other disease. If diabetics are monitored regularly by their ophthalmologist, this vision loss is almost always avoidable. Yet, tragically, more than half of all people living with diabetes do not get the recommended annual dilated eye exam. As the number of people with Type 2 diabetes rises in the U.S., the CDC projects that the number of adults with diabetic retinopathy will double by the year 2050. Yet 90 percent of diabetic eye disease can be prevented simply by proper regular examinations and treatment and by controlling blood sugar.

27 Oct 2010

AZ-TMJ develops effective treatment for migraine headaches

AZ-TMJ is once again leading the way in innovative and effective treatments for severe cases of Temporomandibular Joint Disorders or TMD. AZ-TMJ has developed a variety of highly effective treatments to greatly reduce the frequency and severity of migraine headaches for a large percentage of sufferers. Approximately 16% to 17% of the population suffers from migraine headaches, which often have a debilitating effect on suffers' daily lives.

27 Oct 2010

Dobkin technique delays brain damage in heart attack victims

After a heart attack and the victim stops breathing, a process of irreversible brain damage starts to occur within 3 to 4 minutes. Or does it?

27 Oct 2010

Stereotactic radiation effective for trigeminal neuralgia

Stereotactic radiation is an effective, long-term treatment for trigeminal neuralgia: a painful condition that occurs with increased frequency in patients with multiple sclerosis (MS). Radiation is noninvasive and has less negative side effects than other treatments, according to the longest follow-up in a study of its kind presented October 31, 2010, at the 52nd Annual Meeting of the American Society for Radiation Oncology (ASTRO).

26 Oct 2010

Salk discovers potential new target for MS

Scientists are closer to solving one of the many mysteries of multiple sclerosis and other demyelinating diseases, thanks to a recent study conducted at the Salk Institute for Biological Studies. The research revealed a previously unknown connection between two ion channels, which, when misaligned, can cause the many bizarre symptoms that characterize the condition.

26 Oct 2010

Two researchers receive European Research Council Starting Grants

Two European Research Council (ERC) Starting Grants worth almost one and a half million euros each over the next five years have been awarded to two researchers from the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch and the Charit Universit-tsmedizin, Berlin in Germany.

25 Oct 2010

Motherhood helps women grow their grey matter: Study

According to the latest research motherhood helps women grow their grey matter. The study was conducted by scientists at the National Institute of Mental Health in Maryland and it showed that the brains of new mothers substantially gained in nerve cells while they coped with the steep learning curve of dealing with a newborn. Also in a bizarre way, mothers who ‘gushed’ the most about their babies showed the greatest growth in key parts of the brain.

24 Oct 2010

Diamyd Medical to divide operations into two business areas

In her comments in today's year end report, Elisabeth Lindner, President and CEO of Diamyd Medical, states that the company has decided to divide its operations into two business areas beginning with the new 2010/2011 fiscal year; Diabetes and Pain.

22 Oct 2010

New findings provide new clues on pathogenetic mechanisms of Alzheimer's disease

Pathological protein deposits linked to Alzheimer's disease and cerebral amyloid angiopathy can be triggered not only by the administration of pathogenic misfolded protein fragments directly into the brain but also by peripheral administration outside the brain.

22 Oct 2010

Scientists discover new cell that may limit inflammation in CNS

Scientists at Barrow Neurological Institute have recently made discoveries about a type of cell that may limit inflammation in the central nervous system - a finding that could have important implications in the treatment of brain disorders such as multiple sclerosis. The research, led by Barrow's Fu-Dong Shi, MD, PhD, was published in the August 2010 issue of The Journal of Experimental Medicine, and simultaneously highlighted in Nature.

22 Oct 2010

Researchers suggest gene therapy may treat patients with major depression

In a report published in the Oct. 20 issue of Science Translational Medicine, researchers at NewYork-Presbyterian Hospital/Weill Cornell Medical Center say animal and human data suggest gene therapy to the brain may be able to treat patients with major depression who do not respond to traditional drug treatment.

22 Oct 2010