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Treatment resistance for deadly form of kidney cancer linked to low mitochondrial content in the cell

Researchers at Karolinska Institutet in Sweden have linked resistance to treatment for a deadly form of kidney cancer to low mitochondrial content in the cell.

27 Jun 2022

Rensselaer scientists secure $3.5 million grant to develop a low-dose, oral COVID antiviral drug

Rensselaer Polytechnic Institute researchers Gaetano Montelione and Christopher Cioffi will use a five-year, $3.5 million grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, to develop a low-dose, oral COVID antiviral drug that can be administered at home.

27 Jun 2022

Review and case study illustrates the challenges of monkeypox

A new paper published in Travel Medicine and Infectious Disease reviews the history of this disease in and outside Africa, with special reference to its clinical difficulties.

27 Jun 2022

Bisphosphonates appear to improve COVID-19 exposure outcomes

A new retrospective study examines the effect of bisphosphonates on COVID-19 outcomes.

27 Jun 2022

LUCID: music, medicine, and machine learning

In this interview, News-Medical speaks to Zoë Thomson, Co-founder and Chief Innovation Officer of LUCID, about how music and machine learning are changing how we approach mental and neuropsychiatric health.

27 Jun 2022

CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

AbbVie today announced the European Medicines Agency's (EMA) Committee for Medicinal Products for Human Use (CHMP) recommended the approval of upadacitinib (RINVOQ® 15 mg, once daily) for the treatment of active non-radiographic axial spondyloarthritis (nr‑axSpA) in adult patients with objective signs of inflammation as indicated by elevated C-reactive protein (CRP) and/or magnetic resonance imaging (MRI), who have responded inadequately to nonsteroidal anti-inflammatory drugs (NSAIDs).*

27 Jun 2022

CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

27 Jun 2022

Specific gene mutations may be responsible for how long someone lives with Parkinson's disease

How long someone lives with Parkinson's disease may be down to specific gene mutations, according to new research presented today at the 8th European Academy of Neurology Congress.

26 Jun 2022

UC San Diego scientists report on the molecular impact of life indoors

Within and upon every human being reside countless microorganisms - the microbiota that help shape and direct the lives of their hosts. A similar phenomenon occurs between people, microbes and the homes they share.

24 Jun 2022

Researchers identify orally efficacious antiviral drug against respiratory syncytial virus

An oral antiviral drug that targets a key part of the respiratory syncytial virus (RSV) polymerase and inhibits the synthesis of viral genetic material has been identified, a finding that could provide an effective treatment against RSV disease, according to researchers in the Center for Translational Antiviral Research at Georgia State University.

24 Jun 2022

Data-driven simulation model projects three key strategies that could save many lives from opioid crisis

A significant challenge in addressing the country's opioid crisis is that policies based on past patterns of behavior may have unintended consequences because those patterns change over time.

24 Jun 2022

‘It’s not a haven’: With limited capacity for abortion care, Minnesota clinics brace for influx

A few minutes west of the Minneapolis-St. Paul International Airport sits a brick, one-story building with opaque windows. From the nearby freeways, most drivers wouldn't recognize it as the location of one of the few clinics in the state that provides abortions.

24 Jun 2022

Study uncovers cryptic vulnerabilities in RET oncogene that could aid in anti-cancer drug design

RET is a receptor protein with tyrosine kinase activity that can transfer a phosphate group from ATP to other molecules modifying their shape and function in signaling pathways that are essential to organogenesis and tissue maintenance.

24 Jun 2022

MD Anderson announces collaborative alliance with Turning Point Therapeutics to advance new treatment options for cancer patients

The University of Texas MD Anderson Cancer Center and Turning Point Therapeutics, Inc., today announced a strategic research and development alliance to expand the evaluation of two of Turning Point's investigational small molecules focusing on precision medicine targets well known in oncology.

24 Jun 2022

Scientists develop suitable human cell line for anti-SARS-CoV-2 drug screening

Scientists have described the development of a modified A549 cell line that shows a robust expression of ACE2 and TMPRSS2 and high susceptibility to SARS-CoV-2 infection.

24 Jun 2022

New molecular information could help develop more effective treatments for melanoma

A new study reveals important molecular information that could help scientists develop more effective treatment and prevention strategies for a difficult-to-treat form of melanoma skin cancer.

24 Jun 2022

New nanoparticles effectively stopped the growth and spread of ovarian, liver tumors in mice

As they grow, solid tumors surround themselves with a thick, hard-to-penetrate wall of molecular defenses. Getting drugs past that barricade is notoriously difficult.

24 Jun 2022

Ultrathin sensor helps measure different biomarkers to perform on-body chemical analysis

Researchers created a special ultrathin sensor, spun from gold, that can be attached directly to the skin without irritation or discomfort. The sensor can measure different biomarkers or substances to perform on-body chemical analysis.

24 Jun 2022

COVID-19 rebound risks similar for Paxlovid and Molnupiravir

In a recent article posted to the medRxiv* preprint server, investigators in the United States illustrated that rebound of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can occur in some patients following molnupiravir and Paxlovid SARS-CoV-2 therapy.

23 Jun 2022

Researchers improve the ability of a protein to repair oxidative DNA damage

Researchers at Karolinska Institutet and SciLifeLab in Sweden describe in a study published in Science how they have improved the ability of a protein to repair oxidative DNA damage and created a new protein function.

23 Jun 2022

Drugs News and Research

Treatment resistance for deadly form of kidney cancer linked to low mitochondrial content in the cell

Rensselaer scientists secure $3.5 million grant to develop a low-dose, oral COVID antiviral drug

Review and case study illustrates the challenges of monkeypox

Bisphosphonates appear to improve COVID-19 exposure outcomes

LUCID: music, medicine, and machine learning

CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

Specific gene mutations may be responsible for how long someone lives with Parkinson's disease

UC San Diego scientists report on the molecular impact of life indoors

Researchers identify orally efficacious antiviral drug against respiratory syncytial virus

Data-driven simulation model projects three key strategies that could save many lives from opioid crisis

‘It’s not a haven’: With limited capacity for abortion care, Minnesota clinics brace for influx

Study uncovers cryptic vulnerabilities in RET oncogene that could aid in anti-cancer drug design

MD Anderson announces collaborative alliance with Turning Point Therapeutics to advance new treatment options for cancer patients

Scientists develop suitable human cell line for anti-SARS-CoV-2 drug screening

New molecular information could help develop more effective treatments for melanoma

New nanoparticles effectively stopped the growth and spread of ovarian, liver tumors in mice

Ultrathin sensor helps measure different biomarkers to perform on-body chemical analysis

COVID-19 rebound risks similar for Paxlovid and Molnupiravir

Researchers improve the ability of a protein to repair oxidative DNA damage

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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