Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Pfizer’s IBRANCE (palbociclib) now approved for use in women with HR+, HER2- metastatic breast cancer

Pfizer Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved a new indication expanding the use of IBRANCE (palbociclib) 125mg capsules, Pfizer’s metastatic breast cancer therapy.

23 Feb 2016

Two Johns Hopkins scientists named among 105 winners of Presidential Early Career Awards

Namandje Bumpus, Ph.D., and Jordan Green, Ph.D., of the Johns Hopkins University School of Medicine are among 105 winners of Presidential Early Career Awards for Scientists and Engineers, which were announced by the White House on Feb. 18.

23 Feb 2016

Consuming dried plums can protect from radiation-induced bone loss

Dr. Nancy Turner, a Texas A&M AgriLife Research scientist in College Station, was one of a team of researchers who recently studied different interventions to protect from radiation-induced bone loss.

23 Feb 2016

FDA-approved VENTANA anti-ALK CDx more accurate than commonly used IHC assay for patient selection

The U.S. Food and Drug Administration approved VENTANA anti-ALK(D5F3)CDx performed more accurately than another commonly used immunohistochemistry (IHC) assay, based on the use of the 5A4 clone, for the selection of patients eligible to receive ALK tyrosine kinase inhibitor (TKI) treatment.

23 Feb 2016

Regulus reports net loss of $7.2 million for fourth quarter 2015

Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, today reported financial results for the fourth quarter and full-year ended December 31, 2015 and provided a summary of recent corporate highlights.

23 Feb 2016

BCRF expands research program with new collaborative breast cancer funding model

The Breast Cancer Research Foundation announced the expansion of its research program with a new collaborative breast cancer funding model—the BCRF Investigator-Initiated Drug Research Program—that will help broaden and accelerate clinical research on treatment strategies for people with breast cancer.

22 Feb 2016

Patient enrollment completed in vepoloxamer Phase 3 study for treatment of sickle cell disease

Mast Therapeutics, Inc., a biopharmaceutical company developing novel, clinical-stage therapies for sickle cell disease and heart failure today announced that it has completed patient enrollment in its Phase 3 clinical study of vepoloxamer for the treatment of patients with sickle cell disease experiencing vaso-occlusive crisis, known as the EPIC study.

22 Feb 2016

CISCRP's first international AWARE for All event to be held in London

The Center for Information and Study on Clinical Research Participation is pleased to announce that its first international AWARE for All event will be held in the UK on 7 March, 2016 from 17:00 to 20:00 at London's Camden Centre on Euston Road.

22 Feb 2016

Newly developed intravital microscopy system proves safe for use in humans

A team of Roswell Park Cancer Institute researchers has developed and evaluated the first intravital microscopy system shown to be safe for use in humans. Writing in the journal Nature Communications, the scientists report that their proprietary technology enabled them, for the first time ever, to visualize tumor blood vessels in real time.

22 Feb 2016

Scientists resolve tumor heterogeneity using innovative DEPArray technology

Using the innovative DEPArray technology, scientists at Silicon Biosystems, a Bologna (Italy) and San Diego (CA, USA) based biotech company, were able to solve one of the biggest limitation in the study of cancer genetic: tumor samples heterogeneity.

22 Feb 2016

Researchers identify common molecular alteration in glioblastoma

Glioblastoma is the most aggressive manifestation of brain tumours. Due to its high invasive capacity and uncontrolled, infiltrating growth, it is particularly difficult to manage. Currently, the treatment for this disease consists of a combination of surgery (when possible), radiation and chemotherapy.

22 Feb 2016

Naldemedine significantly improves opioid-induced constipation in patients with chronic non-cancer pain

Shionogi today announced pivotal phase III study (COMPOSE I) results showing that once-daily treatment with naldemedine significantly improved opioid-induced constipation (OIC) compared to placebo in patients with chronic non-cancer pain.

22 Feb 2016

Lenalidomide trials show potential for expanding lymphoma, leukaemia indications

Positive findings from two clinical trials have been published for the immunomodulatory agent lenalidomide in patients with heavily pretreated mantle cell lymphoma, and in adults with T-cell leukaemia-lymphoma or peripheral T-cell lymphoma.

19 Feb 2016

Regular DBT imaging can increase cancer detection and reduce call backs

The increased cancer detection and reduced call backs associated with 3D mammography, also known as Digital Breast Tomosynthesis (DBT), can be maintained years after a patient's first DBT screening with regularly scheduled DBT imaging, according to a JAMA Oncology study published online today from researchers at the Perelman School of Medicine at the University of Pennsylvania.

19 Feb 2016

Novartis receives FDA Breakthrough Therapy designation for PKC412 (midostaurin)

Novartis announced today that the United States Food and Drug Administration has granted Breakthrough Therapy designation to PKC412 (midostaurin). PKC412 (midostaurin) is an investigational treatment for adults with newly-diagnosed AML who are FLT3 mutation-positive, as detected by an FDA-approved test, and who are eligible to receive standard induction and consolidation chemotherapy.

19 Feb 2016

Majority of LAHNC patients rely on lifestyle-altering cost-coping strategies to manage treatment

The majority of patients with locally advanced head and neck cancers (LAHNC) rely on cost-coping strategies that alter their lifestyle in order to manage the financial burden of their care, according to research presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

19 Feb 2016

Researchers examine molecular profile of HPV-positive oropharyngeal squamous cell carcinoma

Throat cancer patients exposed to both human papillomavirus (HPV) and tobacco smoke demonstrate a pattern of mutations along several key cancer genes, according to research presented today at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

19 Feb 2016

Post-treatment imaging can help detect recurrences of HPV-positive oropharyngeal cancer

For patients treated with definitive radiation therapy (RT) for oropharyngeal cancer caused by human papillomavirus (HPV), the majority of recurrences can be detected by post-treatment imaging at three months and physical exams during the six months following treatment, according to research presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

19 Feb 2016

New way to analyze MRI data may offer treatment guidance for breast cancer patients

For women with the most common type of breast cancer, a new way to analyze magnetic resonance images (MRI) data appears to reliably distinguish between patients who would need only hormonal treatment and those who also need chemotherapy, researchers from Case Western Reserve University report.

19 Feb 2016

Induction chemotherapy fails to improve survival in head and neck cancer patients

Head and neck cancer patients who receive chemotherapy prior to radiation therapy (induction chemotherapy or IC) rather than the standard treatment that combines chemotherapy with radiation (chemoradiation or CRT) show no survival benefit and are less likely to receive a full course of radiation, according to research from the University of Colorado Cancer Center presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

19 Feb 2016

Oncology News and Research

Further Reading

Pfizer’s IBRANCE (palbociclib) now approved for use in women with HR+, HER2- metastatic breast cancer

Two Johns Hopkins scientists named among 105 winners of Presidential Early Career Awards

Consuming dried plums can protect from radiation-induced bone loss

FDA-approved VENTANA anti-ALK CDx more accurate than commonly used IHC assay for patient selection

Regulus reports net loss of $7.2 million for fourth quarter 2015

BCRF expands research program with new collaborative breast cancer funding model

Patient enrollment completed in vepoloxamer Phase 3 study for treatment of sickle cell disease

CISCRP's first international AWARE for All event to be held in London

Newly developed intravital microscopy system proves safe for use in humans

Scientists resolve tumor heterogeneity using innovative DEPArray technology

Researchers identify common molecular alteration in glioblastoma

Naldemedine significantly improves opioid-induced constipation in patients with chronic non-cancer pain

Lenalidomide trials show potential for expanding lymphoma, leukaemia indications

Regular DBT imaging can increase cancer detection and reduce call backs

Novartis receives FDA Breakthrough Therapy designation for PKC412 (midostaurin)

Majority of LAHNC patients rely on lifestyle-altering cost-coping strategies to manage treatment

Researchers examine molecular profile of HPV-positive oropharyngeal squamous cell carcinoma

Post-treatment imaging can help detect recurrences of HPV-positive oropharyngeal cancer

New way to analyze MRI data may offer treatment guidance for breast cancer patients

Induction chemotherapy fails to improve survival in head and neck cancer patients

A best-practice guide for laboratory services in oncology trials eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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