Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

Depressive episodes hard to treat in continuous cycling bipolar disorder

Patients with bipolar disorder who switch directly between mania and depression without a period of euthymia have a poor response to short-term antidepressant treatment, study findings indicate.

3 Dec 2014

SAFit-ligands provide foundation for novel treatment of stress-related psychiatric disorders

The FK506-binding protein 51 (FKBP51) is an established risk factor for stress-related psychiatric disorders such as major depression. Drug discovery for FKBP51 has been hampered by the inability to pharmacologically differentiate against the very similar functional counterplayer FKBP52.

3 Dec 2014

New study shows that brain’s ability to manage stress depends on brain protein

The brain's ability to effectively deal with stress or to lack that ability and be more susceptible to depression, depends on a single protein type in each person's brain, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published November 12 in the journal Nature.

14 Nov 2014

Scientists receive NARSAD Distinguished Investigator Grants for mental health research

The Brain & Behavior Research Foundation today announced the award of NARSAD Distinguished Investigator Grants valued at $1.5 million to 15 scientists, who are full professors or the equivalent, conducting innovative projects in diverse areas of neurobiological and behavioral research.

13 Nov 2014

Study finds that mental health disorders double heart disease, stroke risks

People facing mental health challenges are significantly more likely to have heart disease or stroke, according to a study presented today at the Canadian Cardiovascular Congress.

28 Oct 2014

Analgesics, anti-inflammatory drugs have beneficial effect on treatment of depression

Ordinary over the counter painkillers and anti-inflammatory drugs purchased from pharmacies may also be effective in the treatment of people suffering of depression.

22 Oct 2014

Study reveals that people with stress-related inflammation may suffer from depression

Preexisting differences in the sensitivity of a key part of each individual's immune system to stress confer a greater risk of developing stress-related depression or anxiety, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published October 20 in the Proceedings of the National Academy of Sciences.

21 Oct 2014

Fatty fish intake appears to increase antidepressant response rates

Up to half of patients who suffer from depression (Major Depressive Disorder, or MDD) do not respond to treatment with SSRIs (Selective Serotonin Reuptake Inhibitors). Now a group of Dutch researchers have carried out a study which shows that increasing fatty fish intake appears to increase the response rate in patients who do not respond to antidepressants.

21 Oct 2014

New drug naming system to be presented at ECNP conference in Berlin

What's in a name? Doctors have found that the name of the drug you are prescribed significantly influences how the patient sees the treatment.

20 Oct 2014

Pointers for boosting prophylactic bipolar treatment reported

Patients with newly diagnosed bipolar disorder who have not previously used psychiatric drugs or have short hospital admissions should be targeted for prophylactic treatment, say researchers.

8 Oct 2014

Clinical practice study supports ISBD recommendations

Findings in patients with bipolar disorder given short-term antidepressant treatment support the recent International Society for Bipolar Disorder’s task force recommendations.

2 Oct 2014

New study reports how TMS treatment works in people with depression

On Star Trek, it is easy to take for granted the incredible ability of futuristic doctors to wave small devices over the heads of both humans and aliens, diagnose their problems through evaluating changes in brain activity or chemistry, and then treat behavior problems by selectively stimulating relevant brain circuits.

30 Sep 2014

Brain & Behavior Research Foundation to honor 8 scientists for achievements in psychiatric research

The Brain & Behavior Research Foundation will honor eight scientists with its 2014 Outstanding Achievement Prizes for work delving into psychiatric disorders that affect one in four people. The awards, which celebrate the transformative power of neuroscience and psychiatric research to improve the lives of people with mental illness, will be presented at the Foundation's National Awards Dinner at the Pierre Hotel.

30 Sep 2014

UC Davis research highlights need for better guidance for primary care providers

Short questionnaires used to identify patients at risk for depression are linked with antidepressant medications being prescribed when they may not be needed, according to new research from UC Davis Health System published in the September-October issue of the Journal of the American Board of Family Medicine.

30 Sep 2014

Epidurals and reduced postpartum depression: an interview with Dr. Zakowski

The “maternity blues”, which resolve within 10 days of giving birth, occurs in up to 80% of new moms. A major depressive episode, by Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria, is defined as having at least a 2-week period of persistent depressed mood ...

23 Sep 2014

Researchers identify control mechanism for mood disorders

Researchers at University of California, San Diego School of Medicine have identified a control mechanism for an area of the brain that processes sensory and emotive information that humans experience as "disappointment."

19 Sep 2014

FDA approves Contrave extended-release tablets for chronic weight management

Takeda Pharmaceuticals U.S.A., Inc. and Orexigen® Therapeutics, Inc. jointly announced today that the U.S. Food and Drug Administration has approved Contrave® extended-release tablets as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index of 30 kg/m2 or greater (obese), or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition.

11 Sep 2014

Current issue provides critical review of data concerned with antidepressant drugs

A paper in the current issue of Psychotherapy and Psychosomatics by Giovanni Fava, MD (University of Bologna) provides a critical review of the data concerned with antidepressant drugs.

4 Sep 2014

Review of clinical trials based on administering antidepressants for chronic postsurgical pain

After a systematic review of clinical trials based on administering antidepressants for acute and chronic postsurgical pain, researchers have concluded that more trials are needed to determine whether these drugs should be prescribed for postsurgical pain on a regular basis.

30 Aug 2014

Cancer patients require better treatment for depression

Findings from three research studies have shown that around three quarters of cancer patients who suffer from major depression do not receive treatment for their depression and that a newly developed medical programme has proven more effective than standard care at reducing depression in these patients.

28 Aug 2014

Antidepressant News and Research

Further Reading

Depressive episodes hard to treat in continuous cycling bipolar disorder

SAFit-ligands provide foundation for novel treatment of stress-related psychiatric disorders

New study shows that brain’s ability to manage stress depends on brain protein

Scientists receive NARSAD Distinguished Investigator Grants for mental health research

Study finds that mental health disorders double heart disease, stroke risks

Analgesics, anti-inflammatory drugs have beneficial effect on treatment of depression

Study reveals that people with stress-related inflammation may suffer from depression

Fatty fish intake appears to increase antidepressant response rates

New drug naming system to be presented at ECNP conference in Berlin

Pointers for boosting prophylactic bipolar treatment reported

Clinical practice study supports ISBD recommendations

New study reports how TMS treatment works in people with depression

Brain & Behavior Research Foundation to honor 8 scientists for achievements in psychiatric research

UC Davis research highlights need for better guidance for primary care providers

Epidurals and reduced postpartum depression: an interview with Dr. Zakowski

Researchers identify control mechanism for mood disorders

FDA approves Contrave extended-release tablets for chronic weight management

Current issue provides critical review of data concerned with antidepressant drugs

Review of clinical trials based on administering antidepressants for chronic postsurgical pain

Cancer patients require better treatment for depression

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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