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Bruker introduces breakthrough MALDI-2 source on timsTOF fleX, and further innovations in CCS-enabled 4D proteomics on timsTOF

At the virtual ASMS 2020 Reboot conference, Bruker Corporation today announces a major advance in matrix-assisted laser desorption ionization (MALDI) with the launch of the world’s first commercial MALDI-2 post-ionization (PI) source, which is now available as an option on the timsTOF fleXTM ESI/MALDI mass spectrometer.

From Bruker Daltonics 3 Jun 2020

Breakthrough discovery could lead to treatment of Fragile X syndrome

Scientists at the Hotchkiss Brain Institute, Alberta Children's Hospital Research Institute, and Owerko Centre at UCalgary's Cumming School of Medicine have made a breakthrough discovery that could lead to treatment of Fragile X syndrome, the leading genetic cause of Autism Spectrum Disorder.

2 Jun 2020

Researchers use optical mapping system to observe the effect of hydroxychloroquine

The malaria drug hydroxychloroquine, which has been promoted as a potential treatment for Covid-19, is known to have potentially serious effects on heart rhythms.

1 Jun 2020

Study solves the longstanding mystery of anesthesia

Surgery would be inconceivable without general anesthesia, so it may come as a surprise that despite its 175-year history of medical use, doctors and scientists have been unable to explain how anesthetics temporarily render patients unconscious.

30 May 2020

Biophysicists reveal molecular mechanism behind light-driven sodium pumping

An international research team has for the first time obtained the structure of the light-sensitive sodium-pumping KR2 protein in its active state.

28 May 2020

Thermo Fisher Scientific and Biognosys extend partnership to advance DIA mass spectrometry-based workflows

Thermo Fisher Scientific, the world leader in serving science, and Biognosys, a leading developer of next-generation proteomics solutions, announce they are continuing their collaboration to advance data independent acquisition mass spectrometry-based workflows.

From Thermo Fisher Scientific Inc. 28 May 2020

New Thermo Scientific Proteome Discoverer 2.5 software strengthens laboratory workflows

Scientists in the life sciences can now benefit from upgrades to a suite of analytical software solutions with new features designed to enhance productivity, confidence and accuracy in numerous fields, including proteomics, food safety and biotherapeutic drug development.

From Thermo Fisher Scientific Inc. 28 May 2020

New Orbitrap Exploris 120 mass spectrometer redefines productivity in small molecule applications

Scientists working across small molecule applications require systems that support extensive, in-depth analysis of multiple complex samples, while simultaneously increasing output and decreasing costs.

From Thermo Fisher Scientific Inc. 28 May 2020

Frog brain discovery may pave the way for repairing birth defects in humans

A team of researchers from Tufts University, Universitat de Valencia, and Harvard University has discovered that the brains of developing frog embryos damaged by nicotine exposure can be repaired by using “ionoceuticals” that can help in the recovery of bioelectric patterns in the embryo.

28 May 2020

New replaceable filter for N95 Masks potentially blocks more virus particles

Since the outbreak of COVID-19, there's been a worldwide shortage of face masks -- particularly, the N95 ones worn by health care workers.

21 May 2020

Study pinpoints electrophysiological mechanism behind upper motor neuron disease

Scientists from Northwestern Medicine and the University of Belgrade have pinpointed the electrophysiological mechanism behind upper motor neuron disease, unlocking the door to potential treatments for amyotrophic lateral sclerosis and other neurodegenerative diseases, such as Hereditary Spastic Paraplegia and Primary Lateral Sclerosis.

21 May 2020

Paper-based device measures lithium ion concentration in blood of bipolar disorder patients

A group of Hokkaido University researchers has developed a paper-based device that can easily and cheaply measure lithium ion concentration in blood, which could greatly help bipolar disorder patients.

21 May 2020

Neuroscientists discover anti-aging molecule that repairs age-related DNA damage

MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions.

18 May 2020

Developing innovative radiation treatment for inoperable brain and spinal tumors

An innovative radiation treatment that could one day be a valuable addition to conventional radiation therapy for inoperable brain and spinal tumors is a step closer, thanks to new research led by University of Saskatchewan (USask) researchers at the Canadian Light Source (CLS).

13 May 2020

Research identifies a disease trigger for pancreatitis

One factor contributing to the development of pancreatitis lies in mutations within a cell membrane ion channel that is characterized by its specific permeability for calcium ions.

13 May 2020

Abnormal calcium levels in mitochondria may cause neuronal cell death in Alzheimer's disease

For the first time, using a mouse model of Alzheimer's disease, scientists have documented a link between raised levels of calcium in mitochondria and neuronal death in the living brain.

13 May 2020

New technology enables simultaneous imaging of multiple proteins

Degenerative diseases such as Alzheimer's often involve complex interactions between multiple proteins and other biomolecules.

12 May 2020

Simple molecular reagents to fight against neurodegenerative disorders

Sometimes the most complex problems actually have very simple solutions. A group of South Korean researchers reported an efficient and effective redox-based strategy for incorporating multiple functions into simple molecular reagents against neurodegenerative disorders.

11 May 2020

Predicting the dose for repurposing nitazoxanide in COVID-19

A new study published on the preprint server medRxiv in May 2020 reports a model that could help evolve appropriate dosage protocols for future clinical trials of the repurposed drug nitazoxanide in COVID-19 prevention and treatment. The researchers say, “It was possible to achieve plasma and lung tizoxanide concentrations, using proven safe doses of nitazoxanide, that exceed the EC90 for SARS-CoV-2.”

7 May 2020

Innovative crystal has many promising applications

Spinels are oxides with chemical formulas of the type AB2O4, where A is a divalent metal cation (positive ion), B is a trivalent metal cation, and O is oxygen.

5 May 2020

Ion News and Research

Bruker introduces breakthrough MALDI-2 source on timsTOF fleX, and further innovations in CCS-enabled 4D proteomics on timsTOF

Breakthrough discovery could lead to treatment of Fragile X syndrome

Researchers use optical mapping system to observe the effect of hydroxychloroquine

Study solves the longstanding mystery of anesthesia

Biophysicists reveal molecular mechanism behind light-driven sodium pumping

Thermo Fisher Scientific and Biognosys extend partnership to advance DIA mass spectrometry-based workflows

New Thermo Scientific Proteome Discoverer 2.5 software strengthens laboratory workflows

New Orbitrap Exploris 120 mass spectrometer redefines productivity in small molecule applications

Frog brain discovery may pave the way for repairing birth defects in humans

New replaceable filter for N95 Masks potentially blocks more virus particles

Study pinpoints electrophysiological mechanism behind upper motor neuron disease

Paper-based device measures lithium ion concentration in blood of bipolar disorder patients

Neuroscientists discover anti-aging molecule that repairs age-related DNA damage

Developing innovative radiation treatment for inoperable brain and spinal tumors

Research identifies a disease trigger for pancreatitis

Abnormal calcium levels in mitochondria may cause neuronal cell death in Alzheimer's disease

New technology enables simultaneous imaging of multiple proteins

Simple molecular reagents to fight against neurodegenerative disorders

Predicting the dose for repurposing nitazoxanide in COVID-19

Innovative crystal has many promising applications

Enhancing confidence in chemical ionization spectrometry data eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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