Neurodegenerative Disease News and Research

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Biogen begins ISIS-SOD1 Rx Phase 1/2 clinical study in patients with amyotrophic lateral sclerosis

Isis Pharmaceuticals, Inc. today announced that its partner, Biogen, has initiated a Phase 1/2 clinical study of ISIS-SOD1 Rx (BIIB067) in patients with amyotrophic lateral sclerosis (ALS).

11 Dec 2015

Low levels of BRCA1 protein in the brain linked to dementia

Mutant forms of breast cancer factor 1 (BRCA1) are associated with breast and ovarian cancers but according to new findings, in the brain the normal BRCA1 gene product may also be linked to Alzheimer's disease. The results, published in Nature Communications, suggest that low levels of BRCA1 protein in the brain may contribute to dementia.

1 Dec 2015

Protein aggregates as harmful as neurodegenerative-disease-related proteins, shows study

Scientists at the forefront of cutting-edge research into neurodegenerative diseases such as Alzheimer’s and Parkinson’s have shown that the mere presence of protein aggregates may be as important as their form and identity in inducing cell death in brain tissue.

20 Nov 2015

CHOP researchers delay symptoms, extend lifespan in animal model of Batten disease

Researchers have taken a significant step forward in developing gene therapy against a fatal neurodegenerative disease that strikes children. By delivering a working version of a gene to produce a key enzyme that is lacking in Batten disease, the scientists delayed symptoms and extended lifespan in dogs with a comparable disease.

12 Nov 2015

Berkeley Lab scientists identify genetic factors that influence neurological disorders and body weight

Many neurological disorders, such as Parkinson's disease and Alzheimer's disease, are marked by impaired motor skills. In addition, growing evidence suggests there's a link between some neurodegenerative diseases and body weight. A recent NIH study, for example, found that adults who are obese or overweight at midlife may be at risk for earlier onset of Alzheimer's disease.

12 Nov 2015

Two studies explore potential new blood tests for Alzheimer's disease

There is increasing evidence that the brain changes of Alzheimer's disease begin decades before memory and thinking problems occur, prompting the need for better methods of early detection for this progressive, fatal brain disease. Consequently, there is a growing school of thought that the most effective future Alzheimer's drug therapies will be administered to those who are at high risk of the disease before cognitive symptoms appear.

10 Nov 2015

Article explores viewpoints on role of mild cognitive impairment in Parkinson's disease

The current issue of Neurodegenerative Disease Management explores evolving viewpoints on the role of mild cognitive impairment in Parkinson's Disease (PD-MCI), a medical issue which currently lacks consensus. Neurodegenerative Disease Management is published by Future Science Group. The article is also available free of charge to members of Neurology Central, FSG's online community for the international neurology community.

5 Nov 2015

Sanford Research scientists develop animal model to study neurodegenerative disease

Sanford Research scientists have developed a pig model for a neurodegenerative disease that could help better treat the disorder and other physiological conditions. The findings of the project are published in Human Molecular Genetics.

4 Nov 2015

Adelaide researchers identify key protein involved in 'super-inflammatory' immune response

Researchers have made another important step in the progress towards being able to block the development of multiple sclerosis (MS) and other autoimmune diseases.

29 Oct 2015

Dementia specialists, PET imaging providers can now register to participate in IDEAS Study

Dementia specialists and PET imaging providers can now register to participate in the Imaging Dementia - Evidence for Amyloid Scanning (IDEAS) Study at Ideas-Study.org.

29 Oct 2015

Franziska Michor named recipient of NYSCF - Robertson Stem Cell Prize

The New York Stem Cell Foundation announced today that Franziska Michor, PhD, is the 2015 recipient of the NYSCF - Robertson Stem Cell Prize for her work pioneering new approaches to study the growth, spread, and treatment of cancer. Her laboratory fuses her passions in mathematics, molecular biology and patient care to investigate how cancers form and progress.

29 Oct 2015

Successful treatment of rare neurodegenerative disease exemplifies potential of precision medicine

A 20-month-old girl suffering from a rare neurodegenerative disease was diagnosed by exome sequencing and successfully treated.

23 Oct 2015

Psychiatric symptoms predate motor onset in Huntington’s disease

Prodromal psychiatric symptoms may be more common in patients with Huntington’s disease than previously thought and worsen as the condition progresses, longitudinal study findings show.

22 Oct 2015

NAM announces election of three new members from UC San Diego School of Medicine

The National Academy of Medicine announced today the election of three new members from University of California, San Diego School of Medicine: Napoleone Ferrara, MD; Christopher K. Glass, MD, PhD; and Roberto Malinow, MD, PhD. Election to NAM is considered among the highest honors in the fields of health and medicine.

20 Oct 2015

Genetic mutation linked to ALS, FTD prevents proteins from entering and exiting the cell's nucleus

Three teams of scientists supported by the National Institutes of Health showed that a genetic mutation linked to some forms of amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD) may destroy neurons by disrupting the movement of materials in and out of the cell's nucleus, or command center where most of its DNA is stored.

19 Oct 2015

MIT researchers developing computer system to help predict effects of disease on brain anatomy

MIT researchers are developing a computer system that uses genetic, demographic, and clinical data to help predict the effects of disease on brain anatomy.

7 Oct 2015

Study shows link between impaired mitochondria, energy failure, and neuronal dysfunction

A new study from the Gladstone Institutes shows for the first time that impairments in mitochondria--the brain's cellular power plants--can deplete cellular energy levels and cause neuronal dysfunction in a model of neurodegenerative disease.

15 Sep 2015

Scientists elucidate genetic interaction that may prove key to development, progression of glaucoma

Scientists at the University of California, San Diego School of Medicine have elucidated a genetic interaction that may prove key to the development and progression of glaucoma, a blinding neurodegenerative disease that affects tens of millions of people worldwide and is a leading cause of irreversible blindness.

11 Sep 2015

USF, FARA to jointly host scientific symposium on Friedreich's ataxia

The University of South Florida will again bring together leading researchers and patients searching for a treatment for Friedreich's ataxia and related disorders at the seventh annual scientific symposium "Understanding Energy for A Cure." The symposium will be held 5 to 8:30 p.m., Thursday, Sept. 17, at the USF Marshall Student Center Ballroom, USF Cedar Circle, Tampa, FL 33620.

2 Sep 2015

Amgen, Novartis collaborate for Alzheimer's disease and migraine programs

Amgen today announced a neuroscience collaboration with Novartis in the areas of Alzheimer's disease and migraine. The collaboration accelerates Amgen's potential entry into Alzheimer's disease by teaming up with Novartis on a differentiated and genetically validated Alzheimer's disease program directed at genetically predisposed individuals at risk of developing Alzheimer's disease.

2 Sep 2015

Neurodegenerative Disease News and Research

Biogen begins ISIS-SOD1 Rx Phase 1/2 clinical study in patients with amyotrophic lateral sclerosis

Low levels of BRCA1 protein in the brain linked to dementia

Protein aggregates as harmful as neurodegenerative-disease-related proteins, shows study

CHOP researchers delay symptoms, extend lifespan in animal model of Batten disease

Berkeley Lab scientists identify genetic factors that influence neurological disorders and body weight

Two studies explore potential new blood tests for Alzheimer's disease

Article explores viewpoints on role of mild cognitive impairment in Parkinson's disease

Sanford Research scientists develop animal model to study neurodegenerative disease

Adelaide researchers identify key protein involved in 'super-inflammatory' immune response

Dementia specialists, PET imaging providers can now register to participate in IDEAS Study

Franziska Michor named recipient of NYSCF - Robertson Stem Cell Prize

Successful treatment of rare neurodegenerative disease exemplifies potential of precision medicine

Psychiatric symptoms predate motor onset in Huntington’s disease

NAM announces election of three new members from UC San Diego School of Medicine

Genetic mutation linked to ALS, FTD prevents proteins from entering and exiting the cell's nucleus

MIT researchers developing computer system to help predict effects of disease on brain anatomy

Study shows link between impaired mitochondria, energy failure, and neuronal dysfunction

Scientists elucidate genetic interaction that may prove key to development, progression of glaucoma

USF, FARA to jointly host scientific symposium on Friedreich's ataxia

Amgen, Novartis collaborate for Alzheimer's disease and migraine programs

Aneuro: A Year of Neuroscience in Review eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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