Polymerase News and Research

RSS

Research reports full efficacy of Sotrovimab against BQ.1.1 viral replication in a non-human primate challenge model

Researchers used a non-human primate model to show that Sotrovimab, a commercial mAb also known as Xevudy, was fully effective against SARS-CoV-2 Omicron BA.5 sub-lineage and its derivatives, such as BQ.1.1.

17 Feb 2023

How specific delivery management interventions are associated with early neonatal SARS-CoV-2 infection and neonatal death

Researchers reviewed the association between specific delivery management interventions and neonatal SARS-CoV-2 infection and neonatal death in less than 28 days of life.

17 Feb 2023

COVID-19 virus can be detected in tears collected by swabbing, research finds

Research led by scientists at the University of São Paulo (USP) in Brazil has found that the coronavirus that causes COVID-19 can be detected in tears collected by swabbing.

16 Feb 2023

Omicron has higher risk of in-hospital mortality compared to influenza

In a recent study published in the journal JAMA Network Open, researchers compared the hospital outcomes of patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant with those of influenza patients in Switzerland, assess the current disease burden due to coronavirus disease 2019 (COVID-19).

16 Feb 2023

Long-COVID associated with a greater likelihood of unemployment

In a recent study published in the journal JAMA Network Open, researchers assessed the unemployment rates among individuals who developed post–coronavirus disease 2019 (COVID-19) condition (PCC) or long COVID after an acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to determine the functional and neurocognitive impairment levels associated with long COVID.

16 Feb 2023

Chest CT findings and pulmonary function in COVID-19 patients

In a recent study published in the Radiology journal, researchers performed the longitudinal evaluation of chest computerized tomography (CT) findings along with pulmonary function in coronavirus disease 2019 (COVID-19) patients.

16 Feb 2023

After recovering from mild to moderate COVID-19, asthma control deteriorates

In a recent study published in the Respiratory Research journal, researchers in Hong Kong assessed the deterioration of asthma control in patients recovering from mild to moderate coronavirus disease 2019 (COVID-19).

16 Feb 2023

Nirmatrelvir–ritonavir found to lower COVID-19 severity outcomes

Researchers evaluated the effectiveness of nirmatrelvir–ritonavir in preventing coronavirus disease 2019 (COVID-19) severity outcomes during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant predominance.

16 Feb 2023

Cohort study examines the incidence of SARS-CoV-2 rebound in patients on oral antivirals

Researchers performed a retrospective population-wide cohort study using anonymized data in Hong Kong, China, between February 26 and July 3, 2022.

16 Feb 2023

Death of a zoo hippopotamus underscores the species’ susceptibility to SARS-CoV-2

A recent study investigated the death of a hippopotamus at a zoo in Hanoi, Vietnam.

16 Feb 2023

Post-COVID-19 CT scans show lung abnormalities persist two years later

In a recent study published in the journal Radiology, researchers longitudinally assessed changes in chest computed tomography (CT) abnormities and lung function among patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Feb 2023

Delayed presentation of MIS-C following COVID-19

Researchers elucidate the pathophysiology of MIS-C and describe the probable reasons for the delayed presentation of the condition following COVID-19.

15 Feb 2023

New insights into the driving factors of COVID-19 dynamics in England

In a recent study posted to the medRxiv* preprint server, researchers provided quantitative estimates of population-level drivers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and infection severity by fitting coronavirus disease 2019 (COVID-19) epidemiological surveillance data from England into dynamic transmission models.

15 Feb 2023

Comparative study on retinoic acid-inducible gene-I of humans and bats

In a recent study posted to the bioRxiv* preprint server, researchers cloned and functionally characterized the virus ribonucleic acid (RNA) sensor, retinoic acid-inducible gene-I (RIG-I), from the microbat Myotis daubentonii (Yangochiroptera suborder) and the megabat Rousettus aegyptiacus (Yinpterochiroptera suborder), and compared them to the human ortholog.

15 Feb 2023

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

In a recent study posted to the bioRxiv* server, researchers examined the vulnerability of Jamaican fruit bats (Artibeus jamaicensis) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Feb 2023

"AutoPLP" technique enables rapid, accurate detection of mutating bacteria and viruses

As we now know from our experience with the COVID-19 pandemic, the microbes responsible for some infections can rapidly mutate into variants that evade detection and treatment.

15 Feb 2023

What is the tolerability profile and rate of recurrent CDI after administrating microbiome therapeutic SER-109 post-antibiotic treatment?

Researchers investigated the tolerability and safety of a microbiome therapy called SER-109 to treat recurrent infections of Clostridioides difficile in adults.

15 Feb 2023