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Study examines role of NLRP3 inflammasome in ventilator-induced lung injury

Mechanical ventilation is often lifesaving, but can also initiate or aggravate lung injury. A new study in the May issue of Anesthesiology examined the role of one particular receptor in the inflammatory pathway, the NLRP3 inflammasome, and whether it impacts ventilator-induced lung injury.

26 Apr 2012

U.S. spends more on cancer care, but gains time in return

A new analysis published in Health Affairs found that American cancer patients lived almost two years longer than those in 10 European countries -- leading the researchers to say that the additional expense is worth it.

12 Apr 2012

Adjusting ventilator to keep breath size and lung pressures lower can reduce death from lung injury

Carefully adjusting mechanical ventilator settings in the intensive care unit to pump smaller breaths into very sick lungs can reduce the chances of dying by as much as 8 percent, according to a study by critical care experts at Johns Hopkins. Study participants were evaluated for two years after their acute lung injury.

28 Mar 2012

FDA approves Discovery Labs' SURFAXIN to prevent Respiratory Distress Syndrome

Discovery Laboratories, Inc., a specialty biotechnology company dedicated to advancing a new standard in respiratory critical care, today announced that the United States Food and Drug Administration (FDA) has approved SURFAXIN (lucinactant) for the prevention of Respiratory Distress Syndrome (RDS) in premature infants at high risk for RDS.

6 Mar 2012

UAB first hospital in Alabama to offer Melody Valve replacement

In many ways Dylan Fields is your typical 15-year-old boy. He loves sports, and plays baseball and soccer for his school, Tallassee High, in Central Alabama. What's not typical about Dylan is his heart defect and, now, the procedure used to repair his heart.

6 Mar 2012

Enrollment complete in Ikaria iNO Pivotal Phase III trial for BPD

Ikaria, Inc., a critical care company focused on developing and commercializing innovative therapies for critically ill patients, today announced that it has enrolled the last patient into its Pivotal Phase III trial investigating the use of inhaled nitric oxide (iNO) in premature infants with bronchopulmonary dysplasia (BPD).

27 Feb 2012

New device offers fresh hope for patients with Motor Neurone Disease

Patients suffering from a devastating disease are being given fresh hope through an innovative trial being led by the Sheffield Institute for Translational Neuroscience (SITraN) and Sheffield Teaching Hospitals.

10 Feb 2012

Study reports Tennessee collaborative improves quality of surgical care

A new study published online today in the Journal of the American College of Surgeons finds hospitals participating in a regional collaborative of the American College of Surgeon's National Surgical Quality Improvement Program (ACS NSQIP-), achieved substantial improvements in surgical outcomes, such as reducing the rates of acute renal failure and surgical site infections.

24 Jan 2012

Ikaria receives FDA orphan drug designation for use of iNO in PAH

Ikaria, Inc., a critical care company focused on developing and commercializing innovative therapies for critically ill patients, today announced that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation for the use of inhaled nitric oxide (iNO) with the INOpulse DS drug-delivery system as a combination product for pulmonary arterial hypertension.

23 Jan 2012

Unrestricted family visitation in adult ICU provides wide-reaching benefits

The unrestricted presence and participation of patients' family members and friends provides wide-reaching benefits, both medically and emotionally, according to a new Practice Alert from the American Association of Critical-Care Nurses.

20 Dec 2011

FDA nod for pediatric Berlin heart

The U.S. Food and Drug Administration (FDA) has approved the Berlin Heart for pediatric patients waiting for heart transplants. The ventricular assist device is similar to the one worn by former Vice President Dick Cheney but scaled down in size for children and babies.

19 Dec 2011

Prevention practices for catheter-associated urinary tract infections lacking in most hospitals

Hospitals are working harder than ever to prevent hospital-acquired infections, but a nationwide survey shows few are aggressively combating the most common one - catheter-associated urinary tract infections.

9 Dec 2011

Massive and consistent changes in inflammatory gene expression seen in trauma, burns

Serious traumatic injuries, including major burns, set off a "genomic storm" in human immune cells, altering around 80 percent of the cells' normal gene expression patterns. In a report to appear in the December Journal of Experimental Medicine, members of a nationwide research collaborative describe the initial results of their investigation into the immune system response to serious injury, findings which have overturned some longstanding assumptions.

8 Dec 2011

AFECTAIR may be an effective alternative to SoC for delivery of inhaled nitric oxide

Discovery Laboratories, Inc. today released new data showing that use of AFECTAIR resulted in as much as a 70 percent reduction in the amount of nitric oxide required to deliver the desired dose of the therapeutic gas when compared with current standard of care.

7 Dec 2011

Move Day at U-M hospitals goes smoothly

Sunday's move from the now former U-M C.S. Mott Children's Hospital, the Von Voigtlander Women's Hospital and the Adult Bone Marrow Transplant Unit to the new facility began at 7:02 a.m. Sunday with a tiny patient - a baby moving from the Neonatal Intensive Care Unit.

6 Dec 2011

HHS, CCSC to recognize healthcare professionals with excellence in preventing HAIs

Teams of critical care professionals and healthcare institutions with a record of reducing or eliminating healthcare-associated infections (HAIs) are encouraged to submit their best practices to a national awards program.

19 Nov 2011

Severity of smoke-inhalation injury may play a role in overall pulmonary inflammatory response

A study of burn patients has found that those who suffered the most severe smoke inhalation also had more inflammation and spent more time on ventilators and in intensive care.

17 Nov 2011

Covidien fourth quarter net sales increase 15% to $3.08 billion

Covidien plc today reported results for the fourth quarter of fiscal 2011.

15 Nov 2011

Teleflex to showcase respiratory solutions, education programs at AARC Congress

Teleflex Incorporated will showcase a number of respiratory solutions and education programs at the annual American Association of Respiratory Care Congress to be held in Tampa, Florida on November 5-8, 2011.

5 Nov 2011

AHRQ awarded $34M in fiscal year 2011 to expand fight against HAIs

The U.S. Department of Health and Human Services' Agency for Healthcare Research and Quality announced that it has awarded $34 million in fiscal year 2011 for grants and contracts to hospitals, academic medical institutions, and health care research organizations to expand the fight against healthcare-associated infections.

5 Nov 2011