Clinical Trial News and Research

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Key features that distinguish Brittle Type 1 Diabetes from stable T1D

Brittle Type 1 Diabetes (BT1D) is listed by the National Institutes of Health as a rare disease impacting some 4500 people in the USA. It is defined as a severe instability of blood glucose (BG) levels, whatever its cause, with frequent and unpredictable episodes of hypoglycemia (low) and or hyperglycemia (high sugars) that disrupts quality of life.

27 Oct 2017

Genetic variability of Helicobacter pylori complicates efforts to develop effective vaccine

Helicobacter pylori is a widespread bacterial pathogen that infects the lining of the stomach, where it can cause ulcers and even cancer. As a new study shows, its genetic variability complicates efforts to develop an effective vaccine.

25 Oct 2017

VICC selected to administer FDA-approved CAR T therapy for treatment of lymphoma patients

Vanderbilt-Ingram Cancer Center has been selected as one of the few authorized treatment centers in the United States approved to administer the first FDA- approved chimeric antigen receptor T cell (CAR T) therapy for treatment of adult patients with a specific type of lymphoma.

25 Oct 2017

Researchers develop new way to genetically engineer T cells for treating leukemia relapse

Researchers at Fred Hutchinson Cancer Research Center and the University of Washington have developed a novel way to genetically engineer T cells that may be effective for treating and preventing leukemia relapse.

25 Oct 2017

Study reveals why Alzheimer's drugs fail in clinical trials

A tremendous amount of Amyloid-β peptide (Aβ) (a peptide of ～40 amino acids) accumulates in the brain of Alzheimer's disease patients. γ-Secretase inhibitors were designed to inhibit the enzymatic activity that produces Aβ. By reducing Aβ production, γ-secretase inhibitors were considered able to treat Alzheimer's disease (Aβ hypothesis).

25 Oct 2017

Proton beam therapy can help improve outcomes in elderly patients with esophageal cancer

A study led by Mayo Clinic researchers has found that proton beam therapy, in combination with chemotherapy, prior to surgery, may be a better option than a combination using traditional radiation therapy techniques with chemotherapy when treating elderly patients with esophageal cancer.

25 Oct 2017

Trial compares long-term effects of psychotherapy and antidepressants on depression symptoms

In the current issue of Psychotherapy and Psychosomatics there are data about the long term-effects of a form of psychotherapy in depression compared to medication.

24 Oct 2017

New molecule could become first treatment against chemotherapy-induced neuropathy

IDIBELL Researchers of the Neuro-Oncology Unit of Bellvitge University Hospital - Catalan Institute of Oncology, led by Dr. Jordi Bruna, have successfully tested a new molecule capable of preventing the development of peripheral neuropathy induced by chemotherapy in cancer patients, especially in colon cancer cases, the third most common neoplasm in the world.

24 Oct 2017

New drug offers hope for treatment of aggressive T-PLL leukemia

Hitherto there has been no adequate treatment available for the rare and highly aggressive malignant blood disease T-PLL leukemia.

24 Oct 2017

Nanodiamonds could prevent infection, improve recovery after root canal treatment

People who undergo root canals may soon have a tiny but powerful ally that could prevent infection after treatment.

24 Oct 2017

Study finds lung cancer driver ALK-fusion in mucosal melanoma

Melanomas caused by sun exposure have been matched with targeted treatments and immunotherapies, in many cases dramatically extending patients' lives. However, there are other kinds of melanoma not related to sun exposure and because they are caused by different genetic changes, they are not susceptible to the same targeted treatments.

23 Oct 2017

Penn researchers provide new insights into how Notch drives growth of B-cell cancers

Notch is one of the most frequently mutated genes in chronic lymphocytic leukemia (CLL), the most common leukemia in adults in the United States. It is also often mutated in other common B cell tumors, such as mantle cell lymphoma.

23 Oct 2017

Magnesium can be key to treat a range of health issues

Magnesium has been hailed as the ‘super supplement’ to give us the boost we need this winter, says experts on BBC Radio Two’s Breakfast Show with Chris Evans.

From BetterYou Ltd 23 Oct 2017

Dana-Farber, Brigham and Women's Cancer Center certified to offer new CAR T-cell therapy

Following a successful clinical trial involving Dana-Farber Cancer Institute and Brigham and Women's Hospital, the first chimeric antigen receptor (CAR) T-cell therapy for adult cancers was approved by the Food and Drug Administration today.

20 Oct 2017

Adipose-derived stem cell clinical trial focuses on non-healing leg wounds

Sanford Health is launching its second adipose-derived stem cell clinical trial - this one to focus on non-healing leg wounds.

20 Oct 2017

New CAR-T cell therapy offers effective option for certain blood cancer patients

Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis is one of the first centers nationwide to offer a new immunotherapy that targets certain blood cancers.

19 Oct 2017

Physical, psycho-social interventions in advanced lung cancer patients improve functional capacity

Physical exercise and psycho-social interventions in patients with advanced stage lung cancer improved functional capacity, which may be linked to quality of life benefits.

19 Oct 2017

Arsenic trioxide could be powerful therapy to extend lives of certain glioblastoma patients

From Sherlock Holmes to Agatha Christie, arsenic is often the poison of choice in popular whodunits. But in ultra-low dosage, and in the right form, this naturally occurring chemical element can be a potent force against cancer.

17 Oct 2017

Scientists receive critical funding to study treatments for three deadly cancers

Immunotherapy for leukemia patients has been nothing short of a miracle. Now scientists hope to use that science and other forms of gene therapy to tackle three of the deadliest forms of cancer: glioblastoma (brain cancer), sarcoma (bone cancer) and ovarian cancer.

17 Oct 2017

Timing is crucial for corticosteroids to aid healing of tendons

A corticosteroid can improve the healing of damaged tendons, but it must be given at the right time, according to a new study from Linköping University in Sweden. In rats, the tendon became twice as strong. The results are presented in the journal Scientific Reports.

17 Oct 2017

Clinical Trial News and Research

Key features that distinguish Brittle Type 1 Diabetes from stable T1D

Genetic variability of Helicobacter pylori complicates efforts to develop effective vaccine

VICC selected to administer FDA-approved CAR T therapy for treatment of lymphoma patients

Researchers develop new way to genetically engineer T cells for treating leukemia relapse

Study reveals why Alzheimer's drugs fail in clinical trials

Proton beam therapy can help improve outcomes in elderly patients with esophageal cancer

Trial compares long-term effects of psychotherapy and antidepressants on depression symptoms

New molecule could become first treatment against chemotherapy-induced neuropathy

New drug offers hope for treatment of aggressive T-PLL leukemia

Nanodiamonds could prevent infection, improve recovery after root canal treatment

Study finds lung cancer driver ALK-fusion in mucosal melanoma

Penn researchers provide new insights into how Notch drives growth of B-cell cancers

Magnesium can be key to treat a range of health issues

Dana-Farber, Brigham and Women's Cancer Center certified to offer new CAR T-cell therapy

Adipose-derived stem cell clinical trial focuses on non-healing leg wounds

New CAR-T cell therapy offers effective option for certain blood cancer patients

Physical, psycho-social interventions in advanced lung cancer patients improve functional capacity

Arsenic trioxide could be powerful therapy to extend lives of certain glioblastoma patients

Scientists receive critical funding to study treatments for three deadly cancers

Timing is crucial for corticosteroids to aid healing of tendons

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