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Genetic screening algorithm can estimate a person's risk of developing chronic kidney disease

A new algorithm developed by researchers at Columbia University can analyze thousands of variants across the genome and estimate a person's risk of developing chronic kidney disease - and it works in people of African, Asian, European, and LatinX descent.

16 Jun 2022

How does gut microbiota impact mental health in 18–25s?

In a recently published article in the International Journal of Molecular Sciences, scientists have described the importance of the gut-brain-microbiota axis in establishing optimal mental health in emerging adulthood (ages 18–25).

16 Jun 2022

Five quick takeaways from a yearlong investigation of medical debt in America

KHN and NPR embarked on a project to understand how widespread medical debt is in America. Here are the most important takeaways of that yearlong investigation:

16 Jun 2022

Drugs used to prevent bone loss may help lower ovarian cancer risk

Medicines used to prevent bone loss may help lower the risk of ovarian cancer according to research by The University of Queensland.

16 Jun 2022

KHN’s ‘What the Health?’: Closing in on covid vaccines for ‘the littles’

Children younger than 5 are the only population not eligible for a covid-19 vaccine in the U.S. But that may be about to change as an advisory committee to the Food and Drug Administration recommends authorization for that group.

16 Jun 2022

UB program secures $12.8 million to improve the quality of global HIV research

The National Institutes of Health (NIH) has awarded $12.8 million to the University at Buffalo School of Pharmacy and Pharmaceutical Sciences to lead a clinical pharmacology quality assurance program for NIH-funded laboratories and research networks across the globe conducting HIV and infectious disease research.

16 Jun 2022

Combination drug strategy activates natural killer cell-mediated immunity to attack tumors

Most skin cancer drugs that activate the immune system work by triggering immune cells, called T cells, to attack tumors, but when T cells are activated for too long, they can wear out and cease to function.

16 Jun 2022

At a Bay Area ‘test-to-treat’ site, few takers for free antivirals

After avoiding movie theaters, restaurants, and gyms for more than two years, Helen Ho decided to take her first big risk since the start of the pandemic to attend her graduation.

16 Jun 2022

100 million people in America are saddled with health care debt

Elizabeth Woodruff drained her retirement account and took on three jobs after she and her husband were sued for nearly $10,000 by the New York hospital where his infected leg was amputated.

16 Jun 2022

Researchers evaluate artemisinin for COVID-19 management

Researchers assessed the effectiveness of artemisinin-based antimalarials in the management of COVID-19.

16 Jun 2022

Youth substance use declined during the pandemic, research shows

The COVID-19 pandemic has given rise to concerns for youth mental health and social well-being, including its potential to spur substance use behaviors.

16 Jun 2022

Moffitt researchers reveal a mechanism leading to drug resistance in prostate cancer

Prostate cancer is the most common cancer among men in the United States. Many patients can live long lives due to early detection and treatment with androgen deprivation therapy.

16 Jun 2022

Multiomics identifies genomic risk factors for COVID-19

In a recent Cell Systems study, researchers utilized the RefMap machine learning algorithm to correlate known genomic variations for severe COVID-19 obtained from large-scale genome-wide association studies (GWAS) with single-cell multiome profiling of human lungs.

16 Jun 2022

Cost of brand-name antiseizure medications increased by 277% from 2010 to 2018, study finds

The cost of brand-name drugs for epilepsy increased by 277% from 2010 to 2018, according to a study published in the June 15, 2022, online issue of Neurology, the medical journal of the American Academy of Neurology.

16 Jun 2022

Researchers identify a signature of three genes linked to positive response to blood cancer therapy

Mount Sinai researchers have for the first time identified genes that predict a good response to a vital new therapy for a blood cancer that can have serious side effects for some patients.

16 Jun 2022

Chemical synthesis, properties, and molecular modeling studies of spiro-indole compounds

In a recent study under review at the Scientific Reports journal and currently posted to the Research Square* preprint server, researchers synthesized and evaluated the antitumoral (against several cancer cell lines) and antiviral [against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)] properties of 3-spiro-indolin-2-ones.

15 Jun 2022

Researchers create first bona fide mouse model of Merkel cell carcinoma

A team of researchers at the University of Michigan Rogel Cancer Center were the first to generate a bona fide mouse model of a Merkel cell carcinoma, a rare and potentially aggressive form of skin cancer.

15 Jun 2022

Drug combinations may help to slow the progression of diabetic kidney disease

A mouse study led by Washington University School of Medicine in St. Louis suggests that combining SGLT2 inhibitors — a newer class of diabetes medications that lowers blood sugar — with older diabetes drugs may help to slow the progression of diabetic kidney disease.

15 Jun 2022

Scientists publish a robust framework to analyze chromosomal instability in human cancers

Scientists have found a way to identify and interpret 'signatures' that reveal the complex genetic causes of some of the deadliest cancers – which often have a survival rate of less than 10%.

15 Jun 2022

Flexible model of care can be effective in treating opioid use disorder

Did you know that more than 26,500 Canadians died from opioid intoxication between January 2016 and September 2021? Or that more than 350,000 people who used drugs containing opioids to relieve their pain did so problematically?

15 Jun 2022