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Insilico Medicine develops highly selective FGFR2/3 dual inhibitor for cancer treatment

Fibroblast growth factor receptors (FGFRs) are critical drivers of oncogenesis in various solid tumors, including urothelial carcinoma, hepatocellular carcinoma, ovarian cancer and lung adenocarcinoma.

7 Feb 2025

Targeting ELK3 could offer new therapy for rheumatoid arthritis

Rheumatoid arthritis (RA) is an inflammatory arthritis characterized by chronic joint inflammation, cartilage degradation, and bone erosion.

7 Feb 2025

Collagen's structural diversity may be greater than previously believed, study suggests

Collagen, the body's most abundant protein, has long been viewed as a predictable structural component of tissues.

7 Feb 2025

Embedded counseling reduces psychological distress in veterinary trainees

Embedded counseling services are becoming increasingly common in veterinary medical programs, but their effectiveness has not historically been measured.

7 Feb 2025

New 3D bioprinted gastric cancer model predicts drug responses

A collaborative research team led by Professor Jinah Jang from the Department of Mechanical Engineering and the Department of Creative IT Engineering at POSTECH (Pohang University of Science and Technology) and Professor Charles Lee from The Jackson Laboratory for Genomic Medicine in the United States has successfully developed a gastric cancer model using 3D bioprinting technology and patient-derived cancer tissue fragments.

7 Feb 2025

New gene modification enhances CAR-T cell effectiveness against cancer

Researchers have identified a method to enhance the effectiveness of a promising cancer treatment. They found that modifying a specific gene improves the ability of immune cells to combat cancer for an extended period, potentially reducing the chance of cancer recurring.

7 Feb 2025

Distinct myeloid-derived suppressor cell populations fuel aggressive brain tumor growth

A type of aggressive, treatment-resistant brain tumor has a distinct population of immune cells that support its growth, according to new research led by investigators at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins University School of Medicine.

7 Feb 2025

UConn receives $400,000 grant for cutting-edge autism research

Just in time for the Super Bowl, researchers at UConn School of Medicine are part of a big win for autism research.

7 Feb 2025

Study reveals differences in allosteric behavior of cAMP receptor proteins in M. tuberculosis

A new study, "Identifying Allosteric Hotspots in Mycobacterium tuberculosis cAMP Receptor Protein" published in Biochemistry, provides key insights into how bacterial cAMP receptor proteins (CRPs) respond differently to the ubiquitous signaling molecule, cyclic AMP (cAMP).

7 Feb 2025

Bio-based "living" material with self-healing properties could revolutionize regenerative medicine

A biomaterial that can mimic certain behaviors within biological tissues could advance regenerative medicine, disease modeling, soft robotics and more, according to researchers at Penn State.

7 Feb 2025

Mild electrical brain stimulation fails to improve motor recovery in stroke survivors

Mild electrical brain stimulation did not further improve motor recovery in stroke survivors, according to late-breaking science presented today at the American Stroke Association's International Stroke Conference 2025.

7 Feb 2025

ESCAPE-MeVO trial advances understanding of stroke treatment for medium-sized vessel blockages

University of Calgary's Hotchkiss Brain Institute researchers with the Calgary Stroke Program at Foothills Medical Centre revolutionized treatment for stroke with the ESCAPE Trial, proving that a clot retrieval procedure known as endovascular thrombectomy (EVT) can dramatically improve patient outcomes after an acute ischemic stroke caused by a blockage in a large-sized blood vessel.

7 Feb 2025

Low vitamin D in first trimester linked to higher preterm birth risk and reduced fetal length

Maternal vitamin D status in early pregnancy is crucial for fetal growth and may reduce the risk of preterm birth, according to recent research findings.

7 Feb 2025

Early immune system changes contribute to lung damage in cystic fibrosis

Despite new medication, cystic fibrosis often leads to permanent lung damage. Working with an international team, researchers from the Technical University of Munich (TUM) have discovered that the disease causes changes in the immune system early in life, presumably even in newborns.

7 Feb 2025

Alcohol and preexisting health conditions raise risk of advanced liver disease

Why do some people who consume a few glasses of alcohol a day develop advanced liver disease while others who drink the same amount don't?

7 Feb 2025

Comprehensive atlas of endothelial cells advances diabetes research

The distinct population of endothelial cells that line blood vessels in the insulin-producing "islets" of the human pancreas have been notoriously difficult to study, but Weill Cornell Medicine investigators have now succeeded in comprehensively detailing the unique characteristics of these cells.

7 Feb 2025

Fear of cancer recurrence disrupts many aspects of breast cancer survivors' lives

Breast cancer is the world's most prevalent cancer. Although earlier detection and targeted treatment have resulted in high survival rates, many breast cancer survivors experience fear of cancer recurrence. For some survivors this fear is occasional, for others it is persistent and often debilitating.

7 Feb 2025

Mayo Clinic develops AI tool to visualize complex biological data

Mayo Clinic researchers have pioneered an artificial intelligence (AI) tool, called OmicsFootPrint, that helps convert vast amounts of complex biological data into two-dimensional circular images.

6 Feb 2025

Childhood and adult trauma may play a role in endometriosis pathogenesis

The University of Barcelona has participated in an international study that has found new evidence linking traumatic experiences and stressful events with endometriosis, a chronic systemic inflammatory disease characterized by the presence of endometrial-like tissue outside the uterus.

6 Feb 2025

Are school takeaway bans just a policy illusion? Students say yes

Most young people are unaware of takeaway exclusion zones near schools, and policies limiting new outlets fail to address unhealthy food access from convenience stores and delivery apps.

6 Feb 2025

Medicine News and Research

Insilico Medicine develops highly selective FGFR2/3 dual inhibitor for cancer treatment

Targeting ELK3 could offer new therapy for rheumatoid arthritis

Collagen's structural diversity may be greater than previously believed, study suggests

Embedded counseling reduces psychological distress in veterinary trainees

New 3D bioprinted gastric cancer model predicts drug responses

New gene modification enhances CAR-T cell effectiveness against cancer

Distinct myeloid-derived suppressor cell populations fuel aggressive brain tumor growth

UConn receives $400,000 grant for cutting-edge autism research

Study reveals differences in allosteric behavior of cAMP receptor proteins in M. tuberculosis

Bio-based "living" material with self-healing properties could revolutionize regenerative medicine

Mild electrical brain stimulation fails to improve motor recovery in stroke survivors

ESCAPE-MeVO trial advances understanding of stroke treatment for medium-sized vessel blockages

Low vitamin D in first trimester linked to higher preterm birth risk and reduced fetal length

Early immune system changes contribute to lung damage in cystic fibrosis

Alcohol and preexisting health conditions raise risk of advanced liver disease

Comprehensive atlas of endothelial cells advances diabetes research

Fear of cancer recurrence disrupts many aspects of breast cancer survivors' lives

Mayo Clinic develops AI tool to visualize complex biological data

Childhood and adult trauma may play a role in endometriosis pathogenesis

Are school takeaway bans just a policy illusion? Students say yes

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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