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Buy and bust: When private equity comes for rural hospitals

When the new corporate owners of two rural hospitals suddenly announced they would stop admitting patients one Friday in March, Kayla Schudel, a nurse, stood resolute in the nearly empty lobby of Audrain Community Hospital: "You'll be seen; the ER is open."

15 Jun 2022

Combination of three technologies makes potential treatment effective against aggressive brain tumor

A drug carrier able to reach the brain, bind to an aggressive type of tumor called glioblastoma multiforme, and release a chemotherapeutic agent has been tested for the first time by Brazilian researchers.

15 Jun 2022

AKT inhibitor miransertib could be a promising new treatment against low-flow vascular malformations

A team of researchers led by Dr. Sandra Castillo and Dr. Mariona Graupera, from the Josep Carreras Leukaemia Research Institute and member of the CIBERONC, have found the AKT inhibitor miransertib could be a new molecular treatment effective against low-flow vascular malformations, a long-awaited milestone.

14 Jun 2022

Emory researchers identify key immune cell type that drives the transition from early to late COVID-19

Determining how SARS-CoV-2, the virus causing COVID-19, moves from an early stage of infection, when patients are largely asymptomatic, into a later stage when people may experience life-threatening inflammation in the lungs, is a critical step in understanding how to target and treat the disease more efficiently.

14 Jun 2022

Temple researcher receives NIH award to study the link between HIV, substance use and heart disease

With prompt diagnosis and the right treatment, people with HIV can live long, healthy lives. In recent years, however, gains in survival among people with HIV have exposed a new concern – an increase in the incidence of early-onset cardiovascular disease associated with long-term HIV.

14 Jun 2022

New research in mice investigates the safety of DNA nanotechnology

Advances in nanotechnology have made it possible to fabricate structures out of DNA for use in biomedical applications like delivering drugs or creating vaccines, but new research in mice investigates the safety of the technology.

14 Jun 2022

New near-infrared probe may aid in early diagnosis of Alzheimer's disease

Inside the body, some seemingly harmless proteins have sinister potential. In the case of Alzheimer's disease, the amyloid-beta (Aβ) protein, which is vital for brain growth, can become tainted and destroy cells, which leads to forgetfulness and memory loss.

14 Jun 2022

Researchers discover specific genetic signals in people who develop severe COVID-19

Researchers from the University of Sheffield and Stanford University in the US have discovered there are specific genetic signals in people who develop severe coronavirus infection.

14 Jun 2022

As Biden fights overdoses, harm reduction groups face local opposition

Casey Malish had just pulled into an intersection in the 2nd Ward when a woman with tattoos and pinkish hair unexpectedly hopped into the back seat of his gray Mazda. He handles outreach for the Houston Harm Reduction Alliance, a nonprofit that helps drug users like her stay alive.

14 Jun 2022

The role of ARF6 in SARS-CoV-2 endocytosis and infection

Researchers assessed the role of adenoside diphosphate (ADP)-ribosylation factor 6 (ARF6) in SARS-CoV-2 infection.

14 Jun 2022

New project seeks to develop a microscopy system for making drug interactions in the liver visible

Bielefeld University is coordinating a new EU-research project that seeks to produce microscopic liver tissue cultures that can survive for 14 days, while also using imaging methods to investigate how liver cells react to combinations of different medications.

14 Jun 2022

OSU researchers study quorum sensing in a gram-negative bacterium that displays social behaviors

Oregon State University scientists have identified proteins that prevent a bacterial cell from becoming misguided by its own messaging, allowing it to instead wait for collective communication from its group.

13 Jun 2022

Study demonstrates a potential way to stimulate the formation of new insulin-producing cells

Researchers at Karolinska Institutet in Sweden show how a molecule that they have identified stimulates the formation of new insulin-producing cells in zebrafish and mammalian tissue, through a newly described mechanism for regulating protein synthesis.

13 Jun 2022

Risk of severe COVID-19 in adults with immune-mediated inflammatory diseases and those on immune-modifying therapies

Researchers assessed the risk of severe COVID-19 in adults with immune-mediated inflammatory diseases and those on immunomodulatory therapies.

13 Jun 2022

Potential applications of bioactive molecules present in fruit peels

A recent study published in Current Issues in Molecular Biology reviewed the potential biological applications of fruit peel extracts.

13 Jun 2022

Probiotic bacteria may enhance anti-cancer activities of tamoxifen to reduce ER+ breast cancer risk

Probiotic bacteria may enhance anti-cancer activities of the breast cancer drug tamoxifen and other endocrine-targeted therapies, which could help reduce the risk of estrogen receptive positive (ER+) breast cancer, suggests a new study presented Monday at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

13 Jun 2022

Stem cell-based therapy shows potential to provide blood sugar control in patients with high-risk type 1 diabetes

An investigative stem cell-based therapy called PEC-Direct, designed to act as a replacement pancreas, has the potential to provide blood sugar control in patients with high-risk type 1 diabetes, suggests a clinical study presented Saturday, June 11 at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

13 Jun 2022

Drugs News and Research

Buy and bust: When private equity comes for rural hospitals

Combination of three technologies makes potential treatment effective against aggressive brain tumor

AKT inhibitor miransertib could be a promising new treatment against low-flow vascular malformations

Emory researchers identify key immune cell type that drives the transition from early to late COVID-19

Temple researcher receives NIH award to study the link between HIV, substance use and heart disease

New research in mice investigates the safety of DNA nanotechnology

New near-infrared probe may aid in early diagnosis of Alzheimer's disease

Researchers discover specific genetic signals in people who develop severe COVID-19

As Biden fights overdoses, harm reduction groups face local opposition

The role of ARF6 in SARS-CoV-2 endocytosis and infection

New project seeks to develop a microscopy system for making drug interactions in the liver visible

OSU researchers study quorum sensing in a gram-negative bacterium that displays social behaviors

Study demonstrates a potential way to stimulate the formation of new insulin-producing cells

Risk of severe COVID-19 in adults with immune-mediated inflammatory diseases and those on immune-modifying therapies

Potential applications of bioactive molecules present in fruit peels

Probiotic bacteria may enhance anti-cancer activities of tamoxifen to reduce ER+ breast cancer risk

Stem cell-based therapy shows potential to provide blood sugar control in patients with high-risk type 1 diabetes

New molecule kills a broad spectrum of hard-to-treat cancers

Using artificial intelligence to discover new antivirals against COVID-19 and future pandemics

Using a harmless amoeba to protect children from dangerous infections

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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