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Father's age can affect offspring lifespan, mice study shows

How does the father's age at conception affect his children? Researchers at the German Center for Neurodegenerative Disease and fellow scientists have studied this question in mice.

20 Feb 2018

Researchers identify fifteen genes that determine our facial features

Researchers from KU Leuven and the universities of Pittsburgh, Stanford, and Penn State have identified fifteen genes that determine our facial features. The findings were published in Nature Genetics.

19 Feb 2018

Liquid biopsies could be used as new predictive marker for metastatic TNBC

A clinically relevant "liquid biopsy" test can be used to profile cancer genomes from blood and predict survival outcomes for patients with metastatic triple negative breast cancer, according to new research published by a multi-institutional team of researchers with The Ohio State University Comprehensive Cancer Center -- Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, the Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard.

19 Feb 2018

Gene editing tool used to detect cancer

Researchers have developed a DNA detection system that can detect the presence of bacterial and viral DNA, which could be a valuable diagnostic tool for a range of disorders.

16 Feb 2018

Study reveals how carbohydrate-restricted diet improves metabolism

New details about how a carbohydrate-restricted diet improves metabolism were revealed in a study published today, which could lead to improved treatments for non-alcoholic fatty liver disease.

15 Feb 2018

Pioneering research could provide novel insight into how genomic information is read

Pioneering new research could offer a fascinating new insight into how genomic information is read. The human genome contains thousands of genes, but to get the information from a gene requires it to be copied.

13 Feb 2018

Hints to aging lurk in fruit flies’ germline stem cells

Little hints of immortality are lurking in the stem cells of fruit flies. Stem cells that produce sperm use a genetic trick to stay perpetually young across generations, researchers at the University of Michigan Life Sciences Institute have discovered. Certain sections of the fruit fly genome get shorter with age. But remarkably, some reproductive cells can repair the shrinkage, the researchers report in the journal eLife.

13 Feb 2018

Scientists develop Scanpy software to analyze enormous single-cell data

Scientists from the Helmholtz Zentrum München have developed a program that is able to help manage enormous datasets.

13 Feb 2018

Novel approach to studying cancer can lead to new ways of diagnosis and treatment

A novel approach to studying cancer has enabled researchers to group about 10,000 human cancers of 32 different types into 10 classes based on the molecular pathways that drive tumor growth.

12 Feb 2018

Scientists use novel epigenetic-centered techniques to inhibit cancer metastases

In one of the first successes of its kind, researchers from Case Western Reserve University School of Medicine and six other institutions have inhibited the spreading of cancer cells from one part of the body to another.

12 Feb 2018

Polyploid cells can protect the liver against cancer formation, study shows

Researchers at the Children's Medical Center Research Institute at UT Southwestern have discovered that cells in the liver with whole genome duplications, known as polyploid cells, can protect the liver against cancer.

12 Feb 2018

UNC gene therapy scientists uncover viral barcode to penetrate blood-brain barrier

Gene therapies promise to revolutionize the treatment of many diseases, including neurological diseases such as ALS. But the small viruses that deliver therapeutic genes can have adverse side effects at high doses.

11 Feb 2018

Molecular 'magnets' could help develop better immunotherapies for cancer patients

Chemicals that attract specialized immune cells toward tumors could be used to develop better immunotherapies for cancer patients, according to new research published in Cell.

9 Feb 2018

Undergraduate researcher discovers genes linked to glioblastoma

When Leland Dunwoodie, an undergraduate researcher in biochemistry, approached his PI about wanting to start research on "some human stuff" in the spring of 2016, he didn't imagine it would lead to the discovery of 22 genes that are implicated in glioblastoma, the most aggressive type of brain cancer.

9 Feb 2018

Using CRISPR To Produce Induced Pluripotent Stem Cells

An interview with Dr. Sheng Ding about using a modified version of the CRISPR-Cas9 system to produce induced pluripotent stem cells.

9 Feb 2018

Scientists develop ultrasound-propelled nanomotors for active delivery of Cas9-sgRNA complex

In cancer research, the “Cas-9–sgRNA” complex is an effective genomic editing tool, but its delivery across the cell membrane to the target (tumor) genome has not yet been satisfactorily solved. American and Danish scientists have now developed an active nanomotor for the efficient transport, delivery, and release of this gene scissoring system.

9 Feb 2018

Researchers develop safe, potent mRNA vaccine adjuvants that can elicit effective immune response

Production of conventional vaccines, which involves the use of live-attenuated or purified protein subunits of pathogens, is a long and complex process. Nucleic acid vaccines are safer alternatives, and allow easy adjustment of antigen to target specific pathogens.

9 Feb 2018

Genome News and Research

Father's age can affect offspring lifespan, mice study shows

Researchers identify fifteen genes that determine our facial features

Liquid biopsies could be used as new predictive marker for metastatic TNBC

Gene editing tool used to detect cancer

Study reveals how carbohydrate-restricted diet improves metabolism

Pioneering research could provide novel insight into how genomic information is read

Hints to aging lurk in fruit flies’ germline stem cells

Scientists develop Scanpy software to analyze enormous single-cell data

Novel approach to studying cancer can lead to new ways of diagnosis and treatment

Scientists use novel epigenetic-centered techniques to inhibit cancer metastases

Polyploid cells can protect the liver against cancer formation, study shows

UNC gene therapy scientists uncover viral barcode to penetrate blood-brain barrier

Molecular 'magnets' could help develop better immunotherapies for cancer patients

Undergraduate researcher discovers genes linked to glioblastoma

Using CRISPR To Produce Induced Pluripotent Stem Cells

Scientists develop ultrasound-propelled nanomotors for active delivery of Cas9-sgRNA complex

Researchers develop safe, potent mRNA vaccine adjuvants that can elicit effective immune response

Compounds isolated from rattlesnake's venom show promise to fight against hepatitis C

Scientists identify special pair of RNA scissors with many functions

Researchers solve crystal structure for enzyme that plays key role in DNA methylation

Genetics & Genomics - Second Edition eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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