Immune System News and Research

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Regulating gut bacteria could calm chemo side effects, reduce cognitive problems

In a new study, scientists observed several simultaneous reactions in mice given a common chemotherapy drug: Their gut bacteria and tissue changed, their blood and brains showed signs of inflammation, and their behaviors suggested they were fatigued and cognitively impaired.

11 Nov 2019

Juvenile immune arthritis – new treatments wanted

Juvenile immune arthritis (JIA) is a severely undertreated condition, and new medications are badly needed to relieve the signs and symptoms of the illness, according to a new study presented at the 2019 ACR/ARP Annual Meeting.

11 Nov 2019

Methotrexate reduces joint damage in hand osteoarthritis

A new study presented at the 2019 ACR/ARP meeting shows that methotrexate stopped further damage to the hand joints and even perhaps improved bone remodeling in patients with osteoarthritis (OA) of the hand, when they were assessed at 3 and 12 months.

11 Nov 2019

Rheumatoid arthritis: biologics useful in young and old alike

A new study presented at the 2019 ACR/ARP Annual Meeting says that all rheumatoid arthritis (RA) patients, irrespective of their age, benefit to a similar extent from the use of biologic drugs in their treatment. The study measured improvement in disease parameters 48 weeks after the beginning of therapy to establish this conclusion.

11 Nov 2019

Study compares ultrasound versus conventional strategies in early rheumatoid arthritis

Researchers have found that using the information form ultrasound technology in the treatment protocol did not affect the outcome of the patients with Rheumatoid arthritis. The study titled, “Ultrasound versus Conventional Treat-To-Target Strategies in Early Rheumatoid Arthritis: Magnetic Resonance Imaging Outcome Data from a 2-year Randomized Controlled Strategy Trial,” was presented at the 2019 ACR/ARP Annual Meeting.

11 Nov 2019

New textbook on mysterious and deadly cytokine storm syndrome

There's no telling where the call will come from, or when. But Randy Cron, M.D., Ph.D., professor of pediatrics and medicine at UAB, knows to expect them.

11 Nov 2019

Future drugs aimed at halting cell-inactivation process may help prevent Parkinson's disease

In neurodegenerative conditions like Parkinson's disease, a specific group of neurons start to die one by one, causing movement problems and other symptoms. Scientists have long focused on finding out why these neurons die. Now it turns out, they might not even be dead.

11 Nov 2019

New way to measure white blood cell function provides prognostic information about patients with sepsis

Caring for a patient with sepsis requires walking a treatment tightrope. Clinicians must identify the pathogen that is causing a patient's infection, carefully monitor the patient's response to antibiotics and supportive measures and race against the clock to prevent potential organ failure and death.

11 Nov 2019

New blood filtering system could draw disease from the body using magnets

An engineer has developed a new technology that could draw deadly infections such as malaria from the body using magnets.

11 Nov 2019

Adding a specific immune molecule can boost efficacy of rabies vaccine

Every year, more than 59,000 people around the world die of rabies and there remains no cheap and easy vaccine regimen to prevent the disease in humans. Now, researchers report in PLOS Neglected Tropical Diseases that adding a specific immune molecule to a rabies vaccine can boost its efficacy.

From PLOS ONE 11 Nov 2019

Cancer patients with RA treated with immune checkpoint inhibitors likely to experience a flare

A new study found that cancer patients with a pre-existing autoimmune disease receiving immune checkpoint inhibitors as treatment are likely to experience a flare.

11 Nov 2019

Study shows how glucocorticoid hormones control sugar and fat levels over the course of 24 hours

For the first time, a study led by researchers at Helmholtz Zentrum München and the German Center for Diabetes Research shows how glucocorticoid hormones, such as cortisol, control sugar and fat levels differently during day and night, feeding and fasting, rest and activity, over the course of 24 hours.

10 Nov 2019

Research discovers link between biomarker for RA and industrial air pollutants

New, late-breaking research discovered that there are significant associations between anti-citrullinated protein bodies, a characteristic biomarker for rheumatoid arthritis, and industrial emissions of fine particles matter and sulfur dioxide.

10 Nov 2019

New technique to detect common cause for diseases related to thrombotic microangiopathies

There is a group of diseases whose symptoms have a common origin: a lesion in the endothelial tissue that covers the inside of the blood vessels.

8 Nov 2019

Genetic diversity impacts efficacy of cancer immunotherapy

The constant battle against infectious pathogens has had a decisive influence on the human immune system over the course of our evolution.

8 Nov 2019

Scientists discover role for vitamin D in melanoma

A new study published in Cancer Research suggests that high levels of vitamin D may reduce the aggressive nature of melanoma cells and improve survival rates.

8 Nov 2019

Breakthrough research discovers new way to slow progression of diabetic kidney disease

With World Diabetes Day (14th November) on the horizon new breakthrough research from Monash University has discovered a way to slow the progression of kidney disease in people with diabetes.

8 Nov 2019

UK to be transformed into global hub for next-generation radiotherapy research

The UK will be transformed into a global hub for radiotherapy research, pioneering the use of the latest techniques such as FLASH radiotherapy and artificial intelligence, with a new £56 million research network announced by Cancer Research UK today (Monday).

8 Nov 2019

Fight for Sight-funded research identifies potential alternative to treat corneal infections, sight loss

A researcher from the University of Nottingham has discovered a possible alternative to traditional anitbiotics to treat corneal infections.

8 Nov 2019

National effort to develop implantable bio-artificial kidney achieves key milestone

The Kidney Project, a national effort to develop an implantable bio-artificial kidney that could eliminate the need for dialysis, will announce a key milestone in a November 7, 2019 presentation at the American Society of Nephrology Kidney Week 2019 conference in Washington, DC.

7 Nov 2019

Immune System News and Research

Regulating gut bacteria could calm chemo side effects, reduce cognitive problems

Juvenile immune arthritis – new treatments wanted

Methotrexate reduces joint damage in hand osteoarthritis

Rheumatoid arthritis: biologics useful in young and old alike

Study compares ultrasound versus conventional strategies in early rheumatoid arthritis

New textbook on mysterious and deadly cytokine storm syndrome

Future drugs aimed at halting cell-inactivation process may help prevent Parkinson's disease

New way to measure white blood cell function provides prognostic information about patients with sepsis

New blood filtering system could draw disease from the body using magnets

Adding a specific immune molecule can boost efficacy of rabies vaccine

Cancer patients with RA treated with immune checkpoint inhibitors likely to experience a flare

Study shows how glucocorticoid hormones control sugar and fat levels over the course of 24 hours

Research discovers link between biomarker for RA and industrial air pollutants

New technique to detect common cause for diseases related to thrombotic microangiopathies

Genetic diversity impacts efficacy of cancer immunotherapy

Scientists discover role for vitamin D in melanoma

Breakthrough research discovers new way to slow progression of diabetic kidney disease

UK to be transformed into global hub for next-generation radiotherapy research

Fight for Sight-funded research identifies potential alternative to treat corneal infections, sight loss

National effort to develop implantable bio-artificial kidney achieves key milestone

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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