Inflammation News and Research

RSS

Researchers discover how chromosomal instability allows cancer cells to avoid immune defenses

Cancer cells are known for spreading genetic chaos. As cancer cells divide, DNA segments and even whole chromosomes can be duplicated, mutated, or lost altogether. This is called chromosomal instability, and scientists at Memorial Sloan Kettering have learned that it is associated with cancer's aggressiveness.

28 Dec 2020

Scientists identify distinct sub-types of angiosarcomas to allow for targeted treatment

A new study led by clinician-scientists from the National Cancer Centre Singapore, with collaborators from research institutions worldwide, has found that angiosarcomas have unique genomic and immune profiles which allow them to be classified into three different subtypes.

28 Dec 2020

The evolving role of platelet-rich plasma in cosmetic procedures

Platelet-rich plasma (PRP) treatment, which involves injecting a small amount of a patient's own blood to release various growth factors from platelets, continues to increase in popularity.

28 Dec 2020

Immunologic modeling of COVID-19 severity and chronicity

In a new study by researchers at Universidad de Costa Rica and other institutions, a bioinformatics approach is used to determine whether Chronic COVID-19 (CC) might have a distinct immunologic signature compared to the mild to moderate (MM) or the severe/critical COVID-19.

24 Dec 2020

Higher BMI linked to increased risk of SARS-CoV-2 infection

Researchers at the University of Miami Miller School of Medicine, USA, revealed that the spike-specific immunoglobulin G antibodies in obese people are negatively associated with body mass index (BMI) and serum levels of proinflammatory and metabolic markers of pulmonary inflammation.

24 Dec 2020

Thymus gland works to prevent miscarriage, diabetes in pregnant women

An international research team led by the University of British Columbia (UBC) has uncovered for the first time the importance of a small gland tucked behind the sternum that works to prevent miscarriage and diabetes in pregnant women.

24 Dec 2020

FDA authorizes first device to treat patients with walled-off pancreatic necrosis

Today, the U.S. Food and Drug Administration authorized marketing of the EndoRotor System to resect (cut out) and remove necrotic (dead) tissue for patients with walled-off pancreatic necrosis (WOPN), a potentially deadly condition which can occur several weeks after an episode of severe acute pancreatitis, often requiring tissue removal.

23 Dec 2020

Study uncovers a new paradigm for the role of the thymus in pregnancy

How the immune system adapts to pregnancy has puzzled researchers for decades. An international team of researchers, including scientists from IMBA – Institute of Molecular Biotechnology of the Austrian Academy of Sciences – has now discovered that important changes in the thymus occur in order to prevent miscarriages and gestational diabetes.

23 Dec 2020

SARS-CoV-2 infection shown to reduce the expression of vitamin D pathway components

A recent computational study from India implicated a dysregulated vitamin D pathway in the pathobiology of the infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – and opened the door for experimental validation of these observations.

23 Dec 2020

Cell-mediated immunity may be more important than neutralizing antibodies in COVID-19 outcome

A new study sheds light on some important differences between asymptomatic and symptomatic patients with coronavirus disease 2019 (COVID-19).

23 Dec 2020

Researchers use fruit fly model to understand COVID-19-related neurological complications

Researchers claim to have reproduced disease mechanisms due to coronavirus disease 2019 (COVID-19) in the fruit fly, Drosophila, while also providing proof of the efficacy of one drug against these disease processes. If validated, these findings represent a new understanding of how the virus causes neurological symptoms that could help develop more effective therapies.

23 Dec 2020

Researchers test effects of full doses of anticoagulants in COVID-19 patients

Three clinical trial platforms working together to test the effects of full doses of anticoagulants (blood thinners) in COVID-19 patients have paused enrollment for one group of patients.

23 Dec 2020

Phase 2/3 COVID-19 study evaluates safety, potential identification of preliminary efficacy signals

Top-line data from the 270-patient global Phase 2/3 COVID-19 study expected Q1/2021. Top-line data from the 40-patient U.S. Phase 2 study of opaganib in severe COVID-19 expected in the coming days; this non-powered study was designed to evaluate safety and potential identification of preliminary efficacy signals in support of the global Phase 2/3 study of opaganib.

23 Dec 2020

Alterations in fetal microglia may lead to developmental and psychiatric disorders

Researchers at the Kobe University Graduate School of Medicine have revealed that alterations in fetal microglia resulting from maternal inflammation could contribute towards the onset of developmental and psychiatric disorders.

23 Dec 2020

Novel tantalum-loaded hydrogel for rapid control of excessive bleeding

There are many different events which may lead to excessive and uncontrolled bleeding within the body. This can occur as a result of inflammation and ulcerations, abnormalities in the blood vessels or trauma-related injuries.

22 Dec 2020

SARS-CoV-2 antibody levels and types differ by disease severity, study finds

Researchers have measured the antibody levels and types in hospitalized coronavirus disease 2019 (COVID-19) patients with different disease severity. Their results suggest gut immune pathways could play a role in reducing virus-based inflammation and recovery.

22 Dec 2020

Inflammation News and Research

Researchers discover how chromosomal instability allows cancer cells to avoid immune defenses

Scientists identify distinct sub-types of angiosarcomas to allow for targeted treatment

The evolving role of platelet-rich plasma in cosmetic procedures

Immunologic modeling of COVID-19 severity and chronicity

Higher BMI linked to increased risk of SARS-CoV-2 infection

Thymus gland works to prevent miscarriage, diabetes in pregnant women

FDA authorizes first device to treat patients with walled-off pancreatic necrosis

Study uncovers a new paradigm for the role of the thymus in pregnancy

SARS-CoV-2 infection shown to reduce the expression of vitamin D pathway components

Cell-mediated immunity may be more important than neutralizing antibodies in COVID-19 outcome

Researchers use fruit fly model to understand COVID-19-related neurological complications

Researchers test effects of full doses of anticoagulants in COVID-19 patients

Phase 2/3 COVID-19 study evaluates safety, potential identification of preliminary efficacy signals

Alterations in fetal microglia may lead to developmental and psychiatric disorders

Novel tantalum-loaded hydrogel for rapid control of excessive bleeding

SARS-CoV-2 antibody levels and types differ by disease severity, study finds

Immune-inflammatory mediators indicate that rejection and tissue injury can be avoided with drugs

Researchers detect novel IRAK4 mutations in infant with encephalitis and HHV6 reactivation

Study provides new insights into the molecular underpinnings of Duchenne muscular dystrophy

High altitude experts explain pneumolysis caused by COVID-19

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News