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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Researchers develop new approach to protect stem cell recipients from graft-versus-host disease

Stem cell transplants can save lives, for example in patients with leukemia. However, these treatments are not free of risks. One complication that may occur is graft-versus-host disease (GVHD), basically donor-derived immune cells attacking the recipient’s body.

21 Apr 2017

Study reveals potential therapeutic target for kidney fibrosis

When the kidneys - vital organs for filtering the body's entire blood supply - become injured, it can set in motion an unfortunate chain of events that leads to a decline in health.

20 Apr 2017

SLU researchers make advances in understanding plaque-causing protein in neurological disorders

In a recent paper published in the Journal of Biological Chemistry Yuna Ayala, Ph.D., assistant professor of biochemistry and molecular biology at Saint Louis University, and her research team made advances in understanding how a protein causes damaging plaques to build up in neurodegenerative illnesses like amyotrophic lateral sclerosis (ALS) and a form of dementia called frontotemporal lobar degeneration.

19 Apr 2017

Researchers report new evidence that defective HIV proviruses distract immune system

Researchers at Johns Hopkins and George Washington universities report new evidence that proteins created by defective forms of HIV long previously believed to be harmless actually interact with our immune systems and are actively monitored by a specific type of immune cell, called cytotoxic T cells.

19 Apr 2017

Researchers use CRISPR technology to create new strain of red-eyed mutant wasps

Researchers at UC Riverside's Akbari lab have brought a new strain of red-eyed mutant wasps into the world.

19 Apr 2017

Researchers show how dengue virus employs multiple tactics to evade immune detection

For the human body to mount an immune response to a viral infection, host cells must identify the viral invader and trigger a signaling pathway. This signal then prompts the immune system to attack and subdue the pathogen.

19 Apr 2017

New blood test can accurately, quickly identify genetic mutations linked to NSCLC

Identification of a specific genetic mutation in patients with non-small-cell lung cancer (NSCLC) helps clinicians select the best treatment option. Potential NSCLC patients usually undergo invasive tissue biopsy, which may often be unnecessary and delays treatment.

19 Apr 2017

Air pollution may directly affect biology of upper airways to cause chronic sinus problems

Although human population studies have linked air pollution to chronic inflammation of nasal and sinus tissues, direct biological and molecular evidence for cause and effect has been scant.

18 Apr 2017

Study shows possibility to reduce antipsychotic use among nursing home residents with dementia

The use of antipsychotic medication in nearly 100 Massachusetts nursing homes was significantly reduced when staff was trained to recognize challenging behaviors of cognitively impaired residents as communication of their unmet needs, according to a new study led by Jennifer Tjia, MD, MSCE, associate professor of quantitative health sciences.

17 Apr 2017

Scientists solve structure of protein crucial to reproduction and spread of Zika virus

Zika virus is a mosquito-borne infectious disease linked to certain birth defects in infants in South and Central America and the United States.

11 Apr 2017

Researchers map gene activity to reveal how the liver performs different functions

If you get up in the morning feeling energetic and clearheaded, you can thank your liver for manufacturing glucose before breakfast time. Among a host of other vital functions, it also clears our body of toxins and produces most of the carrier proteins in our blood.

11 Apr 2017

Research finding could offer new way to fight deadly pancreatic cancer

Pancreatic cancer, most frequently pancreatic ductal adenocarcinoma (PDAC), is the most lethal and aggressive of all cancers. Unfortunately, there are not many effective therapies available other than surgery, and that is not an option for many patients.

10 Apr 2017

Penn State researchers develop nanoprobes to rapidly isolate rare cancer markers

A nanoscale product of human cells that was once considered junk is now known to play an important role in intercellular communication and in many disease processes, including cancer metastasis.

10 Apr 2017

Rutgers scientists reveal structure of TB drug target and identify new inhibitors

Rutgers University scientists have determined the three-dimensional structure of the target of the first-line anti-tuberculosis drug rifampin. They have also discovered a new class of potential anti-tuberculosis drugs that kill rifampin-resistant and multi-drug-resistant tuberculosis bacteria.

7 Apr 2017

Researchers show how cellular stress regulates production of hemoglobin

Our ability to breathe oxygen is critical to our survival. This process is mediated by the hemoglobin in our blood, which carries oxygen. Since air contains less oxygen on high mountains, the body is under pressure to make hemoglobin rapidly -- a stressful time.

4 Apr 2017

ANGLE's Parsortix system shows high sensitivity, purity in gene expression analysis of head and neck cancers

ANGLE plc, the specialist medtech company, is delighted to announce that the University of Athens and Attikon University Hospital, Greece are today presenting highly encouraging results from their work with ANGLE’s Parsortix system in head and neck squamous cell carcinomas at the American Association for Cancer Research conference 2017, in Washington DC.

4 Apr 2017

Scientists develop novel technique to screen non-coding DNA of genome for diseases

Researchers have developed a method to swiftly screen the non-coding DNA of the human genome for links to diseases that are driven by changes in gene regulation.

4 Apr 2017

Horizon 2020 program selects Precision NanoSystems’ NanoAssemblr platform to develop RNA medicines

Precision NanoSystems NanoAssemblr platform has been selected for the controlled manufacture of nanomedicines as part of the multinational B-SMART (Brain-Specific, Modular and Active RNA Therapeutics) translational research project.

From Precision NanoSystems Inc. 3 Apr 2017

Researchers shed light on how immune cells weaken with age

Researchers from the European Bioinformatics Institute, University of Cambridge, the Wellcome Trust Sanger Institute and the Cancer Research UK–Cambridge Institute have shed light on a long-standing debate about why the immune system weakens with age.

3 Apr 2017

QIAGEN announces commercialization of AdnaTest kit for clinical research in prostate cancer

QIAGEN N.V. today announced it is commercializing the Research use only AdnaTest Prostate Cancer Panel AR-V7 to detect the androgen receptor splice variant 7 (AR-V7) from liquid biopsies to investigate resistance to potential drugs for advanced prostate cancer.

From QIAGEN Manchester Limited 31 Mar 2017

RNA News and Research

Further Reading

Researchers develop new approach to protect stem cell recipients from graft-versus-host disease

Study reveals potential therapeutic target for kidney fibrosis

SLU researchers make advances in understanding plaque-causing protein in neurological disorders

Researchers report new evidence that defective HIV proviruses distract immune system

Researchers use CRISPR technology to create new strain of red-eyed mutant wasps

Researchers show how dengue virus employs multiple tactics to evade immune detection

New blood test can accurately, quickly identify genetic mutations linked to NSCLC

Air pollution may directly affect biology of upper airways to cause chronic sinus problems

Study shows possibility to reduce antipsychotic use among nursing home residents with dementia

Scientists solve structure of protein crucial to reproduction and spread of Zika virus

Researchers map gene activity to reveal how the liver performs different functions

Research finding could offer new way to fight deadly pancreatic cancer

Penn State researchers develop nanoprobes to rapidly isolate rare cancer markers

Rutgers scientists reveal structure of TB drug target and identify new inhibitors

Researchers show how cellular stress regulates production of hemoglobin

ANGLE's Parsortix system shows high sensitivity, purity in gene expression analysis of head and neck cancers

Scientists develop novel technique to screen non-coding DNA of genome for diseases

Horizon 2020 program selects Precision NanoSystems’ NanoAssemblr platform to develop RNA medicines

Researchers shed light on how immune cells weaken with age

QIAGEN announces commercialization of AdnaTest kit for clinical research in prostate cancer

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