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Heart failure drug could be effective in treating leukemia

Canadian researchers followed their intuition that a drug initially intended for heart failure could be effective in treating cancer. Those efforts have borne fruit, as demonstrated by their work published in the Journal of Experimental and Clinical Cancer Research.

13 Jun 2019

Rapid rise in Big Data facilitates digital transformation of healthcare

The unprecedented implications of digital health innovations, being co-produced by the mainstreaming and integration of artificial intelligence, the Internet of Things, and cyber-physical systems in healthcare, are examined in a new technology horizon-scanning article.

13 Jun 2019

Norovirus structures could help develop therapeutics to fight food-borne illness

Noroviruses are a leading cause of food-borne illness outbreaks, accounting for 58% of all outbreaks and cause 685 million cases worldwide each year. There is no effective therapeutic against them. Having knowledge of the intricate structure of the outer layer of noroviruses, the capsid, which allows the virus to attach to its human host, could help in vaccine development.

13 Jun 2019

Apolipoproten E appears to be new potential druggable target for Alzheimer's

Apolipoproten E is a major genetic risk factor for the development of Alzheimer's disease, yet the protein tends to be understudied as a potential druggable target for the mind-robbing neurodegenerative disease.

13 Jun 2019

Researchers develop first blood-brain barrier chip using stem cells

Researchers at Ben-Gurion University of the Negev and Cedars-Sinai Medical Center in Los Angeles have, for the first time, duplicated a patient's blood-brain barrier, creating a human BBB chip with stem cells, which can be used to develop personalized medicine and new techniques to research brain disorders.

13 Jun 2019

Study uncovers trigger for cachexia

Among all major cancers, pancreatic cancer has the highest rate of death - 93 percent of patients die within five years of diagnosis.

13 Jun 2019

More screening and new treatments needed for sickle cell disease

The promise of new treatments for sickle cell disease, a group of inherited red blood cell disorders, has never been so great, but it will only be realized if there is constant investment in health policies such as programs for screening newborns, especially in sub-Saharan Africa, where most cases occur.

13 Jun 2019

HIB-vaccinated children show improved anthropometric, cognitive, and schooling outcomes

India accounts for the highest number of Haemophilus influenzae type b cases and Hib- associated deaths in the world.

13 Jun 2019

People with obstructive sleep apnea have higher risk of involuntary job loss

Recently unemployed people with undiagnosed obstructive sleep apnea have a higher risk of having lost a job multiple times, according to preliminary results from a new study.

13 Jun 2019

New technology harnesses bacterial jumping genes for precise DNA integration

A new discovery by researchers at Columbia University Vagelos College of Physicians and Surgeons could fix one of the major shortcomings of current gene-editing tools, including CRISPR, and offer a powerful new approach for genetic engineering and gene therapy.

13 Jun 2019

UAMS-developed noninvasive device detects melanoma in earliest stages

A University of Arkansas for Medical Sciences research team led by Vladimir Zharov, Ph.D., D.Sc., has demonstrated the ability to detect and kill circulating tumor cells in the blood using a noninvasive device called Cytophone that integrates a laser, ultrasound and phone technologies.

13 Jun 2019

FAU researcher receives the Ernst Jung Career Advancement Award for Medical Research

The Jung Foundation for Science and Research has awarded the young gastroenterologist Dr. Sebastian Zundler from the Chair of Internal Medicine I at FAU the Ernst Jung Career Advancement Award for Medical Research 2019.

13 Jun 2019

Research evaluates prenatal care providers' understanding of alcohol exposure and screening practices

There is no amount, pattern or timing of alcohol use during pregnancy proven safe for a developing fetus. Repeat: there is no amount, pattern or timing of alcohol use during pregnancy proven safe for a developing fetus.

13 Jun 2019

New approach could help in treating brain tumors, other rare cancers

Large randomized clinical trials can uncover biomarkers that indicate which cancer treatments are likely to work best for individual patients. But it's been challenging to find these biomarkers in rarer cancers where such robust data aren't available.

13 Jun 2019

Research aims to use orange peels for improving heart health

You've heard an apple a day keeps the doctor away. Now orange peels may improve your heart health.

13 Jun 2019

New robust and efficient methods for the production of new peptide drugs

Many important natural products such as antibiotics, immunosuppressants, or anti-cancer drugs are produced by microorganisms.

13 Jun 2019

Saunas induce as much physical strain as moderate exercise

Most people assume that their blood pressure falls after a sauna, which is why this is often thought of as relaxing. This may be true in the long-term, but during the sauna session itself, surprisingly, the blood pressure rises just as if you were having a short moderately strenuous workout, according to a new study. This increases the workload on the heart.

13 Jun 2019

Researchers reveal underlying mechanism that protects genetic transcripts in cells

The cell contains transcripts of the genetic material, which migrate from the cell nucleus to another part of the cell. This movement protects the genetic transcripts from the recruitment of "spliceosomes".

13 Jun 2019

Tetrodotoxin found in pufferfish can provide potent pain relief when given properly

Opioids remain a mainstay of treatment for chronic and surgical pain, despite their side effects and risk for addiction and overdose.

13 Jun 2019

Study shows high levels of success in most patients despite tapered glucocorticoid discontinuation

The results of a randomized controlled trial presented today at the Annual European Congress of Rheumatology demonstrate high levels of treatment success in approximately two thirds of patients despite tapered glucocorticoid discontinuation, while a small loss of disease control was observed at the total study population level.

13 Jun 2019

Research News and Research

Heart failure drug could be effective in treating leukemia

Rapid rise in Big Data facilitates digital transformation of healthcare

Norovirus structures could help develop therapeutics to fight food-borne illness

Apolipoproten E appears to be new potential druggable target for Alzheimer's

Researchers develop first blood-brain barrier chip using stem cells

Study uncovers trigger for cachexia

More screening and new treatments needed for sickle cell disease

HIB-vaccinated children show improved anthropometric, cognitive, and schooling outcomes

People with obstructive sleep apnea have higher risk of involuntary job loss

New technology harnesses bacterial jumping genes for precise DNA integration

UAMS-developed noninvasive device detects melanoma in earliest stages

FAU researcher receives the Ernst Jung Career Advancement Award for Medical Research

Research evaluates prenatal care providers' understanding of alcohol exposure and screening practices

New approach could help in treating brain tumors, other rare cancers

Research aims to use orange peels for improving heart health

New robust and efficient methods for the production of new peptide drugs

Saunas induce as much physical strain as moderate exercise

Researchers reveal underlying mechanism that protects genetic transcripts in cells

Tetrodotoxin found in pufferfish can provide potent pain relief when given properly

Study shows high levels of success in most patients despite tapered glucocorticoid discontinuation

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