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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

New gene-silencing drugs cut cholesterol levels by half in early research

The first in a new class of gene-silencing drugs, known as inclisiran, has been shown to halve cholesterol levels in patients at risk of cardiovascular disease.

21 Mar 2017

Researchers develop new method that uses gene editing to find cancer's weak spots

Genetic mutations that cause cancer also weaken cancer cells, creating an opportunity for researchers to develop drugs that will selectively kill them, while sparing normal cells.

20 Mar 2017

Single-cell transcriptomic analysis uncovers subgroups of colorectal tumors

Combining single-cell genomics and computational techniques, a research team including Paul Robson, Ph.D., director of single-cell biology at The Jackson Laboratory, has defined cell-type composition of cancerous cells from 11 colorectal tumors, as well as adjacent noncancerous cells, a key to more targeted diagnosis and treatment.

20 Mar 2017

Circadian misalignments may favor diabetes development

Like almost all light-sensitive living beings, human beings follow biological rhythms set on a period of about 24 hours.

20 Mar 2017

New markers linked to recurrence of erratic heartbeats in some patients after ablation therapy

Ablation procedures restore a regular heartbeat in patients who have a dangerous, abnormal heart rhythm called atrial fibrillation. But it doesn't always work. Now, a new study suggests that certain molecules are associated with the recurrence of erratic heartbeats in some patients after ablation therapy.

20 Mar 2017

Linking RNA to autoimmune diseases

An interview with Dr. Chase Spurlock, CEO, discussing IQuity's research into IncRNAs and how they are linked to autoimmue diseases.

20 Mar 2017

CD4+ T-cell count may not be helpful to assess ART response in HTLV-1/HIV co-infected patients

The authors compared the CD4+ T-cell counts and HIV-1 RNA viral loads of 383 patients who were either mono-infected with HIV or co-infected with HTLV-1/HIV.

17 Mar 2017

TGen researchers create large dataset of potential biomarkers for diagnosing concussions

Following a three-year study of the Arizona State University football program, researchers at the Translational Genomics Research Institute have created the largest dataset to date of extracellular small RNAs, which are potential biomarkers for diagnosing medical conditions, including concussions.

17 Mar 2017

Scientists identify new toxic pathway for protein aggregates in ALS and FTLD

Led by professor Ludo Van Den Bosch, scientists from Belgium, the UK and the US have identified new processes that form protein "clumps" that are characteristic of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD).

17 Mar 2017

Fat cells take over production of uridine from liver during fasting

How do mammals keep two biologically crucial metabolites in balance during times when they are feeding, sleeping, and fasting? The answer may require rewriting some textbooks.

17 Mar 2017

Innovative strategy uses genetically modified viruses to selectively attack tumor cells

Scientists at the IDIBAPS Biomedical Research Institute and at the Institute for Research in Biomedicine lead a study in which they have designed a new strategy to get genetically modified viruses to selectively attack tumor cells without affecting healthy tissues.

16 Mar 2017

LJI researchers unravel molecular underpinnings of exhausted T cells

One reason we survive into adulthood is that cell-killing T cells usually recognize and eliminate cancerous or pathogen-infected cells.

15 Mar 2017

Researchers suggest potential new way to restore healthy intestinal function in older people

Intestinal stem cells rejuvenate daily so bowels will stay healthy and function normally, but a new study in Cell Reports suggests they also age along with people and lose their regenerative capacity.

15 Mar 2017

Scientists create first model of anorexia nervosa using iPSCs derived from adolescent females

An international research team, led by scientists at University of California San Diego School of Medicine, has created the first cellular model of anorexia nervosa (AN), reprogramming induced pluripotent stem cells (iPSCs) derived from adolescent females with the eating disorder.

14 Mar 2017

New method can precisely track replication of yellow fever virus in host immune cells

Researchers from Princeton University's Department of Molecular Biology have developed a new method that can precisely track the replication of yellow fever virus in individual host immune cells.

14 Mar 2017

Cross-species transmission may play big role in virus evolution than previously thought

On occasion, a virus may jump from one host species to another and adapt to the new host. Such cross-species transmission happens more often than expected, according to new research published in PLOS Pathogens, and it may play a much bigger role in virus evolution than previously thought.

10 Mar 2017

Discovery of link between RNA quality control and longevity may shed light on mechanisms behind aging

The vigors of youth and the greener pastures of yesteryears. Some might refer to these and other similar clichés as nothing more than rose-tinted literations of the past; a cognitive side effect of life.

10 Mar 2017

TSRI researchers develop new drug candidates to target prostate and triple negative breast cancers

Scientists on the Florida campus of The Scripps Research Institute (TSRI) have designed two new drug candidates to target prostate and triple negative breast cancers.

9 Mar 2017

MLL, IBM and Illumina collaborate to build new cognitive technology prototype for improving leukemia treatment

Munich Leukemia Laboratory, a state-of-the-art leukemia and lymphoma diagnostic and research laboratory based in Munich, has teamed up with IBM and Illumina, Inc. to help build a new cognitive technology prototype that aims to help researchers improve leukemia treatment.

From Illumina, Inc. 9 Mar 2017

SETD8 enzyme protects against cellular senescence, research reveals

An enzyme that blocks cellular senescence and its mechanisms has been discovered by a research team from Kumamoto University, Japan. They found that a reduction of the enzyme SETD8, which regulates cell proliferation and gene function, results in the promotion of cell aging features.

8 Mar 2017

RNA News and Research

Further Reading

New gene-silencing drugs cut cholesterol levels by half in early research

Researchers develop new method that uses gene editing to find cancer's weak spots

Single-cell transcriptomic analysis uncovers subgroups of colorectal tumors

Circadian misalignments may favor diabetes development

New markers linked to recurrence of erratic heartbeats in some patients after ablation therapy

Linking RNA to autoimmune diseases

CD4+ T-cell count may not be helpful to assess ART response in HTLV-1/HIV co-infected patients

TGen researchers create large dataset of potential biomarkers for diagnosing concussions

Scientists identify new toxic pathway for protein aggregates in ALS and FTLD

Fat cells take over production of uridine from liver during fasting

Innovative strategy uses genetically modified viruses to selectively attack tumor cells

LJI researchers unravel molecular underpinnings of exhausted T cells

Researchers suggest potential new way to restore healthy intestinal function in older people

Scientists create first model of anorexia nervosa using iPSCs derived from adolescent females

New method can precisely track replication of yellow fever virus in host immune cells

Cross-species transmission may play big role in virus evolution than previously thought

Discovery of link between RNA quality control and longevity may shed light on mechanisms behind aging

TSRI researchers develop new drug candidates to target prostate and triple negative breast cancers

MLL, IBM and Illumina collaborate to build new cognitive technology prototype for improving leukemia treatment

SETD8 enzyme protects against cellular senescence, research reveals

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