Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

U-M study finds shorter sleep duration for 9- to 12-year-old kids is associated with increased risk for being overweight

Diets high in fat and sugar may not be the only things contributing to American children's expanding waistlines. Research findings from the University of Michigan C.S. Mott Children's Hospital suggest that kids who aren't getting enough sleep also may be at an increased risk for being overweight.

5 Nov 2007

New study demonstrates that mindfulness techniques promote health for diabetes patients

A new study has found that patients with diabetes are routinely taught to manage their disease but will be more successful if also taught how to deal with the fear, sadness and anger that comes from having it.

5 Nov 2007

New understanding of gestational diabetes

A protein in the pancreas is giving researchers at the Stanford University School of Medicine their first chance at cracking the code that determines how diabetes develops during pregnancy, a finding that could lead to new treatments for all forms of diabetes.

2 Nov 2007

Increased glucose level is a strong risk factor for colorectal cancer

Diabetes is a very common illness that affects more than 20 million people in the U.S. and it is estimated an additional 54 million Americans have pre-diabetes, a condition that occurs when a person's blood glucose levels are higher than normal but not high enough for a diagnosis of type 2 diabetes.

2 Nov 2007

High-fat diet makes mice susceptible to liver injury

A high fat diet may kill regulatory T cells in the liver, allowing steatosis (simple fatty liver) to develop into steatohepatitis (fatty liver with inflammation), according to the results of a new study in the November issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD).

2 Nov 2007

Research identifies two genes that may play a role in insulin resistance

New research from UAB (University of Alabama at Birmingham) identifies two genes that may play a role in insulin resistance, opening a new avenue for researchers searching for treatments for type 2 diabetes and metabolic syndrome.

28 Oct 2007

A new source of islet cells

The shortage of islet cells limits the development of islet transplantation. One new approach was reported in the October 21 issue of the World Journal of Gastroenterology because of its great significance in enhancing the output of islet cells.

25 Oct 2007

Stem cells from a person's own umbilical cord effectively treat blood and immune disorders, juvenile diabetes

Two separate data abstracts displayed at the annual scientific meeting of the AABB - an international association of medical professionals and institutions focused on transfusion, transplantation and cellular therapy - highlight the increasing therapeutic use of autologous (one's own) cord blood stem cells for transplant and regenerative medicine, including treatments for blood and immune disorders, juvenile diabetes and neurological repair.

22 Oct 2007

New method of oral insulin delivery patented

Syracuse University researchers have designed, tested and patented a new method of oral insulin delivery that can potentially help reduce daily insulin injections for millions of people with diabetes who require therapy for optimal glycemic control.

22 Oct 2007

Exercise improves thinking and reduces diabetes in overweight kids

Just three months of daily, vigorous physical activity in overweight children improves their thinking and reduces their diabetes risk, researchers say.

22 Oct 2007

Longer-living, healthier mouse holds clues to human ageing

A study by scientists at UCL (University College London) shows that mice lacking the insulin receptor substrate (IRS)-1 are more resistant to ageing than normal mice.

22 Oct 2007

Lilly and MacroGenics to develop and commercialize teplizumab

Eli Lilly and Company and MacroGenics, Inc. have announced that the two companies have entered into a global strategic alliance to develop and commercialize teplizumab, a humanized anti-CD3 monoclonal antibody, as well as other potential next generation anti-CD3 molecules for use in the treatment of autoimmune diseases.

19 Oct 2007

Insulin levels affect the brain's dopamine systems

Insulin, long known as an important regulator of blood glucose levels, now has a newly appreciated role in the brain.

18 Oct 2007

Benefit of exenatide has not yet been proven

Since May 2007, a new drug has been available for the treatment of patients with diabetes mellitus type 2 in Germany: exenatide (trade name: Byetta), which is marketed by the manufacturer Eli Lilly.

18 Oct 2007

Discovery of new antibody that helps detect type 1 diabetes

Researchers at the Barbara Davis Center for Childhood Diabetes and University of Colorado at Denver and Health Sciences Center's School of Medicine have discovered a fourth antibody in human blood which will help more accurately predict who is predisposed to type 1 diabetes.

17 Oct 2007

New knowledge about basic cancer biology

Merging technological innovations and new knowledge about basic cancer biology, cancer researchers now target specific molecules involved in critical chemical pathways of cancerous cells.

17 Oct 2007

Insulin signaling and amphetamines

Abuse of psychostimulants such as amphetamine remains a serious public health concern.

17 Oct 2007

New gene findings show that controls of lifespan and cancer have deep, common roots

A person is 100 times more likely to get cancer at age 65 than at age 35. But new research reported in the journal "Nature Genetics" identifies naturally occurring processes that allow many genes to both slow aging and protect against cancer in the much-studied C. elegans roundworm.

15 Oct 2007

Potential health benefits of fish oil in baby formula

Scientists report in the November 2007 issue of the Journal of Lipid Research that adding long-chain polyunsaturated fatty acids - typically found in fish oil - to baby formula may help infants better regulate their blood sugar and make more proteins in their muscle cells.

12 Oct 2007

Biopharmaceutical infrastructure key to lower drug development costs

Improvements to the technology infrastructure for researching and developing new biopharmaceuticals would be expected to save the industry hundreds of millions of dollars annually, according to a new economic study sponsored by the National Institute of Standards and Technology (NIST).

12 Oct 2007