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Diabetes drug can improve the efficiency and efficacy of antibacterial treatments

Old dogs may not learn new tricks, but old drugs can, according to a research team based in China. The collaboration found that Metformin, a small molecule drug that has been used to treat type II diabetes for more than 50 years, can improve the efficiency and efficacy of antibacterial treatments for quick wound-healing in mice.

27 May 2022

Betting on ‘golden age’ of colonoscopies, private equity invests in gastro docs

Mariel needed a new gastroenterologist. Having just moved back to San Antonio, the 30-something searched for a doctor to manage her Crohn's disease, an inflammatory bowel condition that is successfully managed with medications and lifelong monitoring — including regular colonoscopies.

27 May 2022

New therapeutic approach harnesses the body's immune system to protect against brain damage

A therapeutic method for harnessing the body's immune system to protect against brain damage is published today by researchers from the Babraham Institute's Immunology research program.

27 May 2022

New approach could treat brain tumors and also prevent or delay recurrences

Scientists at the University of Michigan Rogel Cancer Center were optimistic when they identified a small molecule that blocked a key pathway in brain tumors.

27 May 2022

Children from historically marginalized groups or poor backgrounds less likely to survive neuroblastoma

Children with high-risk neuroblastoma had worse outcomes if they were from certain racial/ethnic groups or were on public rather than private insurance, despite being treated in clinical trials with standardized protocols, according to a study led by investigators from Dana-Farber/Boston Children's Cancer and Blood Disorders Center.

26 May 2022

New evidence confirms that enterovirus D68 causes acute flaccid myelitis

A case report published in the New England Journal of Medicine provides evidence that enterovirus D68 directly infects spinal cord neurons and that a corresponding robust immune response is present – a direct causation to the polio-like paralyzing illness, acute flaccid myelitis (AFM).

26 May 2022

HMA therapy for patients with myelodysplastic syndrome could potentially activate a sleeping oncogene

Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS) - a group of disorders where there is insufficient production of healthy mature blood cells in the bone marrow - and increasingly in other diseases, but their mechanism of action remains unclear.

26 May 2022

New biomarker may enable rapid, inexpensive diagnosis of Parkinson's disease

Researchers at Kobe University and Hiroshima University have successfully developed a biomarker that will enable Parkinson's disease to be rapidly and inexpensively diagnosed from blood serum samples.

26 May 2022

Gut bacteria can reduce the effectiveness of certain blood pressure drugs

A new study from The University of Toledo College of Medicine and Life Sciences has shown gut bacteria can reduce the effectiveness of certain blood pressure drugs.

26 May 2022

Ketamine uses a previously unknown pathway to produce an antidepressant effect, study finds

For the 280 million people suffering from depression globally, relief cannot come fast enough. Monoaminergic antidepressants, including selective serotonin reuptake inhibitors (SSRIs) take weeks to months to take effect and do not work for more than one in three patients.

26 May 2022

We need to prepare for Monkeypox - now confirmed in 21 countries

Efforts should be made to curb the spread of this virus in order to prevent another pandemic.

25 May 2022

Cryogenic electron microscopy used to determine the structure of fungal ribosome

Most people carry the fungus Candida albicans on their bodies, without this causing many problems. However, a systemic infection with this fungus is dangerous and difficult to treat.

25 May 2022

NYU Abu Dhabi research could pave the way for more effective cancer treatments

A team led by Professor of Biology, Senior Vice Provost of Research at NYU Abu Dhabi, and UAE national Sehamuddin Galadari, has discovered a novel structural modification in AMP-activated protein kinase (AMPK) during anticancer therapy that could pave the way for the development of more effective cancer treatments.

25 May 2022

Common prostate cancer medications may increase risk of serious metabolic or cardiovascular issues

Men taking either of the two most common oral medications for advanced prostate cancer who had also undergone hormone therapy to treat their disease were at higher risk of serious metabolic or cardiovascular issues than patients who were only receiving hormone therapy, Michigan Medicine researchers found.

25 May 2022

Study brings precision medicine closer to reality for diffuse large B cell lymphoma

DNA mutations are essential to the rapid development of an array of antibody-producing immune cells called B cells that collectively can recognize a vast number of specific targets.

25 May 2022

Vaccinated people with breakthrough SARS-CoV-2 infection can experience debilitating long COVID

Even vaccinated people with mild breakthrough COVID-19 infections can experience debilitating, lingering symptoms that affect the heart, brain, lungs and other parts of the body, according to new research from Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care System.

25 May 2022

The effectiveness of sotrovimab vs. molnupiravir in preventing severe COVID-19 outcomes in non-hospitalized high-risk COVID-19 adult patients

Researchers compared the efficacy of sotrovimab and molnupiravir in preventing severe COVID-19 outcomes among non-hospitalized and high-risk COVID-19 patients across England.

25 May 2022

The Blackfeet nation’s plight underscores the fentanyl crisis on reservations

As the pandemic was setting in during summer 2020, Justin Lee Littledog called his mom to tell her he was moving from Texas back home to the Blackfeet Indian Reservation in Montana with his girlfriend, stepson, and son.

25 May 2022

The effectiveness of molnupiravir and nirmatrelvir/ritonavir in reducing hospitalization and deaths in non-hospitalized COVID-19 patients

Researchers assessed the effectiveness of two orally administered antiviral medications, nirmatrelvir/ritonavir, and molnupiravir, in decreasing hospitalization and deaths among real-world non-hospitalized COVID-19 patients in Hong Kong.

25 May 2022

Largest study to date on long COVID identifies a broad list of diagnoses

Researchers characterize post-acute sequelae of SARS-CoV-2 infection.

25 May 2022

Drugs News and Research

Diabetes drug can improve the efficiency and efficacy of antibacterial treatments

Betting on ‘golden age’ of colonoscopies, private equity invests in gastro docs

New therapeutic approach harnesses the body's immune system to protect against brain damage

New approach could treat brain tumors and also prevent or delay recurrences

Children from historically marginalized groups or poor backgrounds less likely to survive neuroblastoma

New evidence confirms that enterovirus D68 causes acute flaccid myelitis

HMA therapy for patients with myelodysplastic syndrome could potentially activate a sleeping oncogene

New biomarker may enable rapid, inexpensive diagnosis of Parkinson's disease

Gut bacteria can reduce the effectiveness of certain blood pressure drugs

Ketamine uses a previously unknown pathway to produce an antidepressant effect, study finds

We need to prepare for Monkeypox - now confirmed in 21 countries

Cryogenic electron microscopy used to determine the structure of fungal ribosome

NYU Abu Dhabi research could pave the way for more effective cancer treatments

Common prostate cancer medications may increase risk of serious metabolic or cardiovascular issues

Study brings precision medicine closer to reality for diffuse large B cell lymphoma

Vaccinated people with breakthrough SARS-CoV-2 infection can experience debilitating long COVID

The effectiveness of sotrovimab vs. molnupiravir in preventing severe COVID-19 outcomes in non-hospitalized high-risk COVID-19 adult patients

The Blackfeet nation’s plight underscores the fentanyl crisis on reservations

The effectiveness of molnupiravir and nirmatrelvir/ritonavir in reducing hospitalization and deaths in non-hospitalized COVID-19 patients

Largest study to date on long COVID identifies a broad list of diagnoses

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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