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Study estimates $1.8 billion in Medicare spending on drugs with accelerated approval

The U.S. federal government spent an estimated $1.8 billion in Medicare funds in 2019 on drugs whose clinical benefits have yet to be confirmed by the Food and Drug Administration, a new study led by researchers from the Johns Hopkins Bloomberg School of Public Health suggests.

24 May 2022

Insilico Medicine nominates novel preclinical candidate targeting 3CL protease for COVID-19 treatment

Insilico Medicine, a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, today announced its nomination of a novel preclinical candidate (PCC) targeting 3C-like (3CL) protease for the treatment of COVID-19.

24 May 2022

Researchers adapt microbubbles to become more potent tools for cancer therapy

Microbubbles can assist with localized drug delivery in a patient's body by popping at a target site to create enhanced permeability of tumor blood vessels.

24 May 2022

Stressful work environment and unemployment linked to opioid misuse among U.S. adults

Two linked studies led by UCLA Fielding School of Public Health researchers have found strong associations between drug misuse generally and opioid misuse specifically among unemployed Americans, who were found to have a 40% higher likelihood to misuse opioids than those working 35-40 hours per week.

24 May 2022

UH experts in cloning and stem cell science take the first step toward unraveling cystic fibrosis

Two nationally recognized experts in cloning and stem cell science from the University of Houston are taking the first step toward limiting the consequences of chronic inflammation in cystic fibrosis (CF) by identifying the source of this persistent and enigmatic inflammation in CF lungs.

24 May 2022

Study identifies a gene that plays an important role in embryo development

A new study co-led by a Cedars-Sinai investigator identified a gene that plays an important role in a biological pathway involved in embryo development.

24 May 2022

Antidiabetic medication may also decrease blood vessel dysfunction associated with aging

An FDA-approved drug to lower blood sugar in adults with Type 2 diabetes also may decrease blood vessel dysfunction associated with aging, according to a new study from the University of Missouri School of Medicine.

24 May 2022

Widely used Type 2 diabetes drug does not prevent breast cancer spread, landmark trial finds

A widely used and inexpensive Type 2 diabetes drug, once hoped to hold enormous promise in treating breast cancer, does not prevent or stop the spread of the most common forms of the disease, according to new findings.

24 May 2022

Tribal pharmacy dispenses free meds and fills gaps for Native Americans in the city

Tucked away on a side street near downtown, the Mashkiki Waakaa'igan Pharmacy offers its Native American clientele the services of any ordinary drugstore — it dispenses critical medication and provides consultation on treatments.

24 May 2022

Efficacy study of Paxlovid and Molnupiravir in real-world settings shows positive results

In a recent study posted to the medRxiv* pre-print server, researchers evaluated the effectiveness of oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antivirals, molnupiravir (Lagevrio) or nirmatrelvir/ritonavir (Paxlovid) in a real-world setting.

24 May 2022

Researchers discover osteogenetic oligodeoxynucleotide that promotes bone differentiation

Bone tissue homeostasis is maintained by a balance between bone formation by osteoblasts and bone resorption by osteoclasts.

23 May 2022

Synthetic biologists interrogate single-celled survivalists to understand stress response

Rice University synthetic biologists and bioengineers are preparing to interrogate some single-celled survivalists to find out how they deal with stress.

23 May 2022

UVA scientists make progress in their longstanding efforts to combat tuberculosis

As headlines focus on COVID-19 and, now, monkeypox, tuberculosis remains one of the great scourges of infectious disease around the world. Approximately 1.5 million people died of tuberculosis in 2020, the World Health Organization reports.

23 May 2022

University of Minnesota receives $66 million to establish new antiviral drug discovery center

The University of Minnesota has received $66 million from the National Institute of Allergy and Infectious Diseases to establish a center to develop antiviral drugs for pandemic-level viruses, including SARS-CoV-2.

23 May 2022

Potential new diagnostic marker predicts successful, efficient development of mammalian egg cells

Researchers at the Centre for Genomic Regulation in Barcelona have identified a potential new diagnostic marker that predicts the successful and efficient development of mammalian egg cells.

23 May 2022

Taste buds can be restrained to enjoy low sodium diet

A taste adaptation intervention lowers salt intake and increases enjoyment of a sodium restricted diet in patients with hypertension, according to a small study presented at ACNAP-EuroHeartCare Congress 2022, a scientific congress of the European Society of Cardiology.

23 May 2022

Drugs News and Research

Study estimates $1.8 billion in Medicare spending on drugs with accelerated approval

Insilico Medicine nominates novel preclinical candidate targeting 3CL protease for COVID-19 treatment

Researchers adapt microbubbles to become more potent tools for cancer therapy

Stressful work environment and unemployment linked to opioid misuse among U.S. adults

UH experts in cloning and stem cell science take the first step toward unraveling cystic fibrosis

Study identifies a gene that plays an important role in embryo development

Antidiabetic medication may also decrease blood vessel dysfunction associated with aging

Widely used Type 2 diabetes drug does not prevent breast cancer spread, landmark trial finds

Tribal pharmacy dispenses free meds and fills gaps for Native Americans in the city

Efficacy study of Paxlovid and Molnupiravir in real-world settings shows positive results

Researchers discover osteogenetic oligodeoxynucleotide that promotes bone differentiation

Synthetic biologists interrogate single-celled survivalists to understand stress response

UVA scientists make progress in their longstanding efforts to combat tuberculosis

University of Minnesota receives $66 million to establish new antiviral drug discovery center

Potential new diagnostic marker predicts successful, efficient development of mammalian egg cells

Taste buds can be restrained to enjoy low sodium diet

Cannabis users need higher levels of sedation during gastric endoscopies

The new MADD movement: Parents rise up against drug deaths

Repurposed drug clofoctol blocks SARS-CoV-2 replication in mouse study

SARS-CoV-2 Omicron subvariants are increasingly escaping immunity

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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