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Stem-like peripheral helper T cells found to sustain inflammation in rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease that affects millions worldwide and can have a devastating impact on patients' lives.

17 Aug 2025

RUNX1C isoform identified as driver of chemoresistance in acute myeloid leukemia

One of the biggest challenges in cancer treatment is that certain cancers reappear after chemotherapy-and an aggressive type of blood cancer called acute myeloid leukemia (AML) is notorious for this.

17 Aug 2025

Alzheimer’s gene risks differ by ancestry, major study reveals 133 new variants

Researchers used whole-genome sequencing from diverse populations to identify 156 variants, including 133 novel ones, linked to Alzheimer’s disease and related dementias. The study highlights ancestry-specific genetic risk and protective factors, challenging one-size-fits-all approaches to dementia genetics.

17 Aug 2025

Study shows probiotics help preterm babies fight antibiotic-resistant bacteria

Researchers found that probiotics help reduce antibiotic-resistant bacteria in the guts of very-low-birth-weight preterm infants, but cannot fully prevent resistance genes from spreading. Antibiotic use still promotes gene swapping, highlighting the limits of probiotics alone in neonatal care.

17 Aug 2025

New generation of CRISPR shows safer path to treating genetic diseases

A new generation of CRISPR technology developed at UNSW Sydney offers a safer path to treating genetic diseases like Sickle Cell, while also proving beyond doubt that chemical tags on DNA - often thought to be little more than genetic cobwebs - actively silence genes.

17 Aug 2025

Origin-recognition complex plays a broad role in the regulation of gene expression

Origin-recognition complex, or ORC, plays an unexpectedly broad role in the regulation of human cell gene expression, according to a study in the journal Cell Reports.

14 Aug 2025

Dual epigenetic marks found to regulate cell identity

Shedding light on what determines how cells become what they are meant to be-nerves, bone, muscles, etc.-can also help researchers understand how diseases develop when these biological programs break down.

14 Aug 2025

Gene editing restores hearing and balance in adult mice with DFNA41 deafness

Zheng-Yi Chen, DPhil, associate scientist at the Eaton-Peabody Laboratories, and Ines and Fredrick Yeatts Chair in Otolaryngology, at Mass Eye and Ear, is the senior and co-corresponding author of a paper published in the Journal of Clinical Investigation, "Single Dose Genome Editing Therapy Rescues Auditory and Vestibular Functions in Adult Mice with DFNA41 Deafness."

14 Aug 2025

Camena Bioscience and Constructive Bio join synthetic biology collaboration to develop plant genomics

Camena Bioscience (Camena), an innovator in enzymatic DNA synthesis, and Constructive Bio (Constructive), a pioneer in whole genome writing, today announced they have joined a collaborative project led by the Max-Planck Institute of Molecular Plant Physiology (MPI-MP), Germany, for a research initiative to develop synthetic chloroplast genomes.

14 Aug 2025

New study explains why neuroblastoma returns years later

Cancer is the leading cause of disease-related death in childhood. This is in part due to cancer-associated genes called oncogenes that can be found far from chromosomes in cell nuclei on ring-shaped DNA inside tumor cells.

14 Aug 2025

HonorHealth taps longevity authority Nicholas J. Schork to lead new research division

Nicholas J. Schork, Ph.D., an international authority on human longevity and health maintenance, has joined HonorHealth Research Institute as Research Director of Longevity, Prevention and Interception.

14 Aug 2025

Disrupting dopamine pathway stops threadworms from burrowing into the skin

Threadworms, which are a type of parasitic nematode, spend a lot of time crawling around on human skin, poking and prodding to find the best place for entry before burrowing in.

13 Aug 2025

New research sheds light on what makes the human brain unique

Research from scientists at University of California San Diego School of Medicine have shed new light on an age-old question: what makes the human brain unique?

13 Aug 2025

mRNA vaccine shows potent efficacy in gastric cancer

Gastric cancer is one of the leading causes of cancer-related mortality worldwide, and peritoneal metastasis, wherein the cancer spreads to the peritoneum or the lining of the abdominal cavity, represents the most common form of recurrence after gastric cancer surgery.

13 Aug 2025

Study finds two-way link between gut bacteria and insomnia

There seem to be reciprocal links between certain groups of gut bacteria and the risk of insomnia, suggests a Mendelian randomization study, published in the open access journal General Psychiatry.

12 Aug 2025

Rising human adaptive potential seen in 2.3.4.4b clade of H5N1

In recent years, there has been growing concern over the H5N1 influenza virus. It was first identified in birds three decades ago and has now gradually found its way to humans.

12 Aug 2025

New method greatly improves the precision of genome editing

A research team headed by the University of Zurich has developed a powerful new method to precisely edit DNA by combining cutting-edge genetic engineering with artificial intelligence.

12 Aug 2025

Global Virus Network committed to the continued development of mRNA vaccines

The Global Virus Network (GVN), a coalition of leading human and animal virologists from 80+ Centers of Excellence and Affiliates in more than 40 countries dedicated to advancing pandemic preparedness, is unequivocally committed to the continued development and deployment of mRNA vaccines and the global scientific collaboration that makes such innovation possible.

12 Aug 2025

Study: Lignin shows strong antiviral and antibacterial properties

Research from the Nanoscience Center of the University of Jyväskylä, Finland, has revealed that lignin, a polyphenol, important for plant structure, has antimicrobial activity against viruses and bacteria.

12 Aug 2025