Infectious Diseases News and Research

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Researchers use innovative approach to uncover hidden bioactive compounds in bacteria

In contrast to humans, bacteria have the remarkable ability to exchange genetic material with each other.

14 Dec 2024

Scientists reveal the spread of highly drug-resistant cholera strain

Scientists from the National Reference Center for Vibrios and Cholera at the Institut Pasteur, in collaboration with the Centre hospitalier de Mayotte, have revealed the spread of a highly drug-resistant cholera strain.

14 Dec 2024

Insilico Medicine gets first clinical milestone payment of $10 million for XL309

Insilico Medicine ('Insilico'), a clinical-stage generative artificial intelligence (AI)-driven drug discovery and development company, today announced that it has received the first clinical milestone payment of $10 million for XL309 (previously known as ISM3091) from Exelixis.

12 Dec 2024

NIH funding supports innovative lupus research using DNA mimic molecules

Lupus causes chronic pain, fatigue, and potentially organ damage for 1.5 million Americans and is a challenge for researchers trying to find better treatments.

12 Dec 2024

New study uncovers role of amino acid serine in preventing food poisoning

Food poisoning is a common, yet unpleasant, illness caused by eating contaminated items. It is sometimes caused by Clostridium perfringens, a pathogen widely found in soil and the intestinal tracts of animals.

12 Dec 2024

New hepatitis B vaccine offers superior protection for people with HIV

A newer vaccine against hepatitis B virus was clearly superior to an older vaccine type in inducing a protective antibody response among people living with HIV who didn't respond to prior vaccination, according to the results of an international study led by a Weill Cornell Medicine investigator.

11 Dec 2024

Skin-friendly bacteria could revolutionize vaccination

Imagine a world in which a vaccine is a cream you rub onto your skin instead of a needle a health care worker pushes into your one of your muscles.

11 Dec 2024

Interim analysis of STOMP study finds no efficacy for tecovirimat in mild to moderate Mpox cases

The antiviral drug tecovirimat did not reduce the time to lesion resolution or have an effect on pain among adults with mild to moderate clade II mpox and a low risk of developing severe disease, according to an interim data analysis from the international clinical trial called the Study of Tecovirimat for Mpox (STOMP).

10 Dec 2024

CHOP study shows safety of rotavirus vaccine in neonatal intensive care unit

Researchers from Children's Hospital of Philadelphia (CHOP) found that transmission of rotavirus vaccine strains in a neonatal intensive care unit (NICU) is rare and without clinical consequences, strongly suggesting that giving the rotavirus vaccine to eligible infants during their hospitalization provides immune benefits that outweigh any risks.

9 Dec 2024

Single mutation in (HPAI) H5N1 influenza virus could increase human transmission risk

A single modification in the protein found on the surface of the highly pathogenic avian influenza (HPAI) H5N1 influenza virus currently circulating in U.S. dairy cows could allow for easier transmission among humans, according to new research funded by the National Institutes of Health (NIH) and published today in the journal Science.

9 Dec 2024

Genetic factors increase prostate cancer risk for African men

Early testing is key to addressing the rise in cases of prostate cancer in Africa - and it doesn't have to be an invasive procedure.

6 Dec 2024

Young adults hit hardest by heat in Mexico, new study shows

Many recent studies assume that elderly people are at particular risk of dying from extreme heat as the planet warms.

6 Dec 2024

Vancouver study reveals surge in severe Shigella cases in homeless population

A recent study published in Clinical Infectious Diseases has uncovered an increase in severe multidrug-resistant (MDR) Shigella sonnei infections, particularly among people experiencing homelessness (PEH) in Vancouver, Canada.

6 Dec 2024

Rethinking public health measures based on game theory

With flu season upon us and coronavirus a persistent threat, Dartmouth researchers propose a new way of thinking about masking and social distancing rules that is more responsive to what people feel is necessary at a given time - and may help increase cooperation.

6 Dec 2024

How measles, whooping cough, and worse could roar back on RFK Jr.’s watch

The availability of safe, effective covid vaccines less than a year into the pandemic marked a high point in the 300-year history of vaccination, seemingly heralding an age of protection against infectious diseases.

6 Dec 2024

Discovery of leptin-responsive neurons offers new hope for obesity treatment

Obesity affects a staggering 40 percent of adults and 20 percent of children in the United States. While some new popular therapies are helping to tackle the epidemic of obesity, there is still so much that researchers do not understand about the brain-body connection that regulates appetite.

5 Dec 2024

WHO grants prequalification to molecular diagnostic test for tuberculosis

The World Health Organization (WHO) has granted prequalification to the molecular diagnostic test for tuberculosis (TB) called Xpert® MTB/RIF Ultra.

5 Dec 2024

New research sheds light on how monkeys avoid hepatitis B infection

Hepatitis B virus (HBV) infection is a leading cause of chronic liver diseases, that spreads among individuals through blood or body fluids.

4 Dec 2024

Great ape museum specimens reveal secrets of DNA virus evolution

Scientists screened great ape museum specimens for DNA viruses, revealing insights into viral evolution and host-virus associations spanning decades.

2 Dec 2024

Researchers discover new cause of cytokine storm in COVID-19

As part of the COVID-19 International Research Team, researchers at the Johns Hopkins Kimmel Cancer Center, Children's Hospital of Philadelphia, the University of Pittsburgh and Weill Cornell Medicine discovered a novel cause of cytokine storm - the extreme inflammatory response associated with increased risk of death in COVID-19 infection.

2 Dec 2024