Polymerase News and Research

RSS

No new SARS-CoV-2 variants detected in China since COVID policy change

In a recent study published in The Lancet, researchers reported the trends in coronavirus disease 2019 (COVID-19) cases and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission in Beijing in 2022.

9 Feb 2023

Study suggests SARS-CoV-2 is likely to only infect placental mammals

Researchers perform ontological and taxonomical analysis of human coronavirus hosts.

9 Feb 2023

Novel COVID-19 protein component vaccine elicits durable immune response in rodents

Researchers describe a novel SARS-CoV-2 spike protein component vaccine called MT-001.

9 Feb 2023

A single base-resolution sequencing methodology that sequences the two most common cytosine modifications in a single workflow

Researchers developed a WGS method that read four canonical DNA bases, viz., adenine (A), cytosine (C), guanine (G), and thymine (T) plus 5mC and 5hmC, epigenetic variants of unmodified C to yield an accurate six-letter digital readout in a single workflow.

9 Feb 2023

Study finds hospitalized obstetric patients with cardiovascular disease and COVID-19 are more symptomatic

Researchers evaluated the impact of cardiovascular disease on the prognosis of maternal SARS-CoV-2) infections.

9 Feb 2023

A microbiota-driven mechanism underlies severity of leishmaniasis infection

In a recent study posed to the medRxiv* preprint server, researchers in Brazil and the United States investigated the probable impact of the skin microbiome microbiota on the outcomes of cutaneous leishmaniasis.

8 Feb 2023

Detection of wild poliovirus type 3 in the Netherlands

Researchers detect wild poliovirus type 3 during the environmental surveillance of poliovirus essential facilities in the Netherlands.

8 Feb 2023

Macrophages suppress Escherichia coli LF82 Gally prophage lytic cycle

Researchers analyze prophages of the LF82 strain of adherent-invasive Escherichia coli to better understand their behavior in vitro and within macrophages.

8 Feb 2023

COVID-19 vaccination increases saliva antibody levels after asymptomatic infection

Researchers correlate SARS-CoV-2 load and neutralizing capacity of all saliva immunoglobulins isotypes in asymptomatic individuals.

8 Feb 2023

Recent findings on T-cell immunity induced by SARS-CoV-2 infection and vaccination in immunocompromised individuals

Researchers discussed studies that explored T-cell immunity induced by SARS-CoV-2 infection and COVID-19 vaccination in cancer patients, individuals with HIV, and recipients of solid organ transplants.

8 Feb 2023

Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

In a recent study published in the International Journal of Molecular Sciences, researchers investigated the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein on human lung macrophage (HLM) activation and angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) expression in human lung macrophages.

7 Feb 2023

Bivalent boosters provide additional protection from BA.5, XBB, and XBB.1.5

In a recent Morbidity and Mortality Weekly Report (MMWR) published on the United States Center for Disease Control and Prevention (US-CDC) website, researchers analyzed data from the Increasing Community Access to Testing (ICATT), a nationwide pharmacy program run in the US for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing.

7 Feb 2023

Mucoactive drugs block SARS-CoV-2 infection

Researchers evaluate the effects of mucociliary active molecules on SARS-CoV-2 infection in vitro.

7 Feb 2023

Study reports two cases of ocular MPox in HIV-infected patients

Researchers review the symptoms, diagnosis, and treatment of ocular Mpox syndrome in men living with HIV infection.

7 Feb 2023

Study characterizes mutations in neuraminidase of human-like H5N1 influenza viruses

A study published in PLOS PATHOGENS describes the prevalence and functions of mutations in neuraminidase enzyme of avian H5N1 influenza viruses that are preferentially selected in human H5N1 influenza viruses.

7 Feb 2023

Study highlights the emergence of S. cerevisiae as an opportunistic fungal pathogen in immunosuppressed patients presenting several severe comorbidities

Researchers from Brazil presented a fatal case of a patient developing Saccharomyces cerevisiae infection and succumbing to septic shock after contracting and recovering from a SARS-CoV-2 infection.

7 Feb 2023

Polymerase News and Research

No new SARS-CoV-2 variants detected in China since COVID policy change

Study suggests SARS-CoV-2 is likely to only infect placental mammals

Novel COVID-19 protein component vaccine elicits durable immune response in rodents

A single base-resolution sequencing methodology that sequences the two most common cytosine modifications in a single workflow

Study finds hospitalized obstetric patients with cardiovascular disease and COVID-19 are more symptomatic

A microbiota-driven mechanism underlies severity of leishmaniasis infection

Detection of wild poliovirus type 3 in the Netherlands

Macrophages suppress Escherichia coli LF82 Gally prophage lytic cycle

COVID-19 vaccination increases saliva antibody levels after asymptomatic infection

Recent findings on T-cell immunity induced by SARS-CoV-2 infection and vaccination in immunocompromised individuals

Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

Bivalent boosters provide additional protection from BA.5, XBB, and XBB.1.5

Mucoactive drugs block SARS-CoV-2 infection

Study reports two cases of ocular MPox in HIV-infected patients

Study characterizes mutations in neuraminidase of human-like H5N1 influenza viruses

Study highlights the emergence of S. cerevisiae as an opportunistic fungal pathogen in immunosuppressed patients presenting several severe comorbidities

A novel multiplexed assay to diagnose Mpox and other viruses

Detecting novel SARS-CoV-2 variants via rapid RT-PCR assays

Study suggests that both mother and infant can contribute to the human milk microbiome

Molnupiravir-related mutational signatures among COVID-19 patients

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

Latest News