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Novel monoclonal antibodies show promise in preventing severe mpox disease

A team from the Microbiology Department at the Icahn School of Medicine at Mount Sinai has discovered three powerful monoclonal antibodies from a person who had previously been infected with mpox (formerly known as monkeypox).

26 Aug 2025

Why a common pesticide may alter brain growth in school-age children

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25 Aug 2025

Researchers identify molecular mechanism behind tamoxifen-related uterine cancer

In a preclinical study, researchers found tamoxifen encourages uterine cell growth; the findings could change how some breast cancers are treated in the future.

22 Aug 2025

New study uncovers a surprising mechanism of resistance to immunotherapy

A new international study led by researchers at Moffitt Cancer Center, the Karolinska Institutet and the University of Texas MD Anderson Cancer Center has uncovered a surprising mechanism of resistance to immunotherapy: cancer's ability to injure nearby nerves.

21 Aug 2025

New formulation of chemotherapy drug opens doors to advanced cancer treatment options

University of Arizona researchers devised a new method to deliver cancer chemotherapy drugs to pancreatic and breast cancer tumors more effectively and with less damage to healthy tissues than standard forms of chemotherapy.

21 Aug 2025

New 'dual-mode' tracer agent enhances precision in prostate cancer procedures

A preclinical evaluation of a new 'dual-mode' tracer agent shows promise in not only helping surgeons image and plan prostate cancer procedures, but also provide them with much more consistent and targeted guidance during surgery.

21 Aug 2025

How dietary formaldehyde links to worsening diabetes and memory loss

A new review reveals how everyday foods and hidden exposures to formaldehyde may fuel insulin resistance and chip away at memory, but also points to dietary patterns and emerging therapies that could help reduce the risk.

20 Aug 2025

Mitochondrial dysfunction in the blood-brain barrier may contribute to neuropsychiatric disease in 22qDS

In a new study led by the University of Pennsylvania School of Veterinary Medicine (Penn Vet) and Children's Hospital of Philadelphia (CHOP), researchers found that mitochondrial dysfunction in the blood-brain barrier (BBB) may lead to neuropsychiatric disease in some patients with 22qDS.

20 Aug 2025

Elevated TMAO levels linked to higher risk of abdominal aortic aneurysms

Cleveland Clinic researchers have discovered a connection between elevated blood levels of TMAO (trimethylamine N-oxide) - a byproduct of gut bacteria digestion of nutrients found in red meat and other animal products - and a higher risk of abdominal aortic aneurysms.

20 Aug 2025

Breakthrough in protein drug delivery could replace lengthy IV infusions

Patients with some cancers, autoimmune diseases, and metabolic disorders often endure time-consuming intravenous (IV) infusions to receive the best protein-based treatments available.

20 Aug 2025

COVID-19 accelerates vascular aging in women

Research shows COVID-19 accelerates vascular aging, especially in women, with implications for long-term cardiovascular health and recovery strategies.

20 Aug 2025

Could chlorophyll become the next antidiabetic therapy?

Research highlights chlorophyll's role in blood sugar regulation and insulin mimicry, though safety risks and lack of human trials warrant caution.

20 Aug 2025

Dengue antibody may block the spread of Zika virus in vulnerable areas of the body

A new study from the University of Alabama at Birmingham reveals that an antibody originally designed to fight dengue virus may also block the spread of Zika virus in vulnerable areas of the body - including the reproductive organs.

19 Aug 2025

Scientists link gut microbes to stronger muscles and healthier aging

Researchers discovered that gut microbes, including Lactobacillus reuteri and L. johnsonii, can enhance muscle strength in aging mice. Co-administration of these strains boosted muscle mass, performance, and reduced inflammation, pointing to a possible microbiome-based strategy for muscle health.

19 Aug 2025

Improving gene therapy safety with human kidney organoids

Ryuji Morizane, MD, PhD, of the Department of Medicine at Massachusetts General Hospital, is the senior/corresponding author of a new paper published in Signal Transduction and Targeted Therapy, "AAV for gene therapy drives a nephrotoxic response via NFκB in kidney organoids."

19 Aug 2025

Why zinc may be the missing nutrient in childhood asthma care

The role of zinc in childhood asthma is critical; deficiency may worsen symptoms, while supplementation could provide a safe, effective treatment alternative.

19 Aug 2025

Early puberty and childbirth tied to accelerated aging and higher disease risk

Reproductive timing matters when it comes to aging and age-related disease. In a study now online at eLife¸ Buck researchers determine that girls who go through puberty (the onset of menstruation) before the age of 11 or women who give birth before the age of 21 have double the risk of developing type 2 diabetes, heart failure and obesity and quadruple the risk of developing severe metabolic disorders.

18 Aug 2025