Small Molecules News and Research

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Scientists identify how cells make choice between various mechanisms to repair DNA

When DNA in the cell nucleus gets damaged, our cells can resort to a variety of repair mechanisms. A recent study published in 'Nature Cell Biology', to which scientists from Helmholtz Zentrum Muenchen made major contributions, elucidates the molecular basis by which a cell makes the choice between these repair mechanisms.

28 Feb 2019

Novel Imaging Methods for Biomedicine

Wei Min has been awarded the Pittcon 2019 Achievement Award. In this interview, he outlines the current imaging challenges in biomedicine and how his novel chemical imaging methods can overcome these.

From Pittcon 26 Feb 2019

Researchers uncover how Gram-negative bacterium delivers toxins that make us sick

Researchers at Binghamton University, State University of New York have uncovered the unique way in which a type of Gram-negative bacterium delivers the toxins that make us sick. Understanding this mechanism may help design better ways to block and eventually control those toxins.

25 Feb 2019

Study finds out similarity in function between healthy retina cell and tumor cell

How is a healthy retina cell like a tumor cell? It hijacks an energy-producing chemical reaction to churn out molecular building blocks. When tumor cells do it, they use the building blocks to make cancer grow and spread. But when retina cells do it, they renew photoreceptor membranes that keep our vision sharp.

22 Feb 2019

New technique could expedite cancer diagnosis, lead to better patient outcomes

The days - or even weeks - spent waiting for the results of a cancer-screening test can feel like an eternity. Especially when early diagnosis and quick action are tied to better outcomes.

20 Feb 2019

Scientists join forces to identify a new approach to fight African sleeping sickness

Scientists working in a range of disciplines joined forces to identify a new approach to combat African sleeping sickness. Fundamental research undertaken under the supervision of Professor Ute Hellmich of Johannes Gutenberg University Mainz has revealed a promising strategy to develop a suitable agent.

20 Feb 2019

Mogrify to accelerate novel IP and cell therapies using $3.7m USD funding

Mogrify today announced a second close on its seed funding, bringing the total raised to $3.7 million USD, and the appointment of Darrin Disley as CEO.

20 Feb 2019

Researchers uncover biochemical pathway that may help identify drugs to treat Alzheimer's

Researchers have uncovered an enzyme and a biochemical pathway they believe may lead to the identification of drugs that could inhibit the production of beta-amyloid protein, the toxic initiator of Alzheimer's disease.

20 Feb 2019

New therapeutic molecules show promise in reversing memory loss related to depression, aging

New therapeutic molecules developed at Toronto's Centre for Addiction and Mental Health show promise in reversing the memory loss linked to depression and aging.

15 Feb 2019

Pill that reverses brain damage could be on the horizon

Researchers have made important progress in designing a drug that could recover brain function in cases of severe brain damage due to injury or disease.

12 Feb 2019

Simple drug cocktail converts neighboring glial cells into functional new neurons

A simple drug cocktail that converts cells neighboring damaged neurons into functional new neurons could potentially be used to treat stroke, Alzheimer's disease, and brain injuries.

8 Feb 2019

Expediting HPLC Method Development in Pharmaceutical Analysis

In this interview, Michael Dong discusses stability-indicating methods such as UHPLC, in pharmaceutical analysis. At Pittcon, Michael will introduce a 3-pronged template approach to HPLC method development.

From Pittcon 30 Jan 2019

Scientists develop new gene therapy that prevents axon destruction in mice

Nerve axons serve as the wiring of the nervous system, sending electrical signals that control movement and sense of touch.

18 Jan 2019

Yeast model may pave way for development of novel therapies for metabolic disorders

There are hundreds of metabolic disorders -- including phenylketonuria, tyrosinemia, maple syrup urine disease and homocystinuria.

17 Jan 2019

Metabolite from berries and pomegranates can mitigate inflammatory bowel disease

Millions of people suffer from inflammatory bowel disease worldwide, either in the form of ulcerative colitis or Crohn's disease, and few effective long-term treatments are available. Chronic intestinal inflammation is a hallmark of IBD.

9 Jan 2019

Washington University scientists find an unknown route for cellular fuel delivery

Scientists at Washington University School of Medicine in St. Louis have identified a previously unknown route for cellular fuel delivery, a finding that could shed light on the process of aging and the chronic diseases that often accompany it.

8 Jan 2019

Researchers develop mouse model to study consequences of fungal infection in the brain

Fungal infections are emerging as a major medical challenge, and a team led by researchers at Baylor College of Medicine has developed a mouse model to study the short-term consequences of fungal infection in the brain.

4 Jan 2019

New technique using microneedles may mean rapid diagnoses of major illnesses

When people are in the early stages of an undiagnosed disease, immediate tests that lead to treatment are the best first steps. But a blood draw -- usually performed by a medical professional armed with an uncomfortably large needle -- might not be quickest, least painful or most effective method, according to new research.

3 Jan 2019

New genetically modified common houseplant purifies air around it

We like to keep the air in our homes as clean as possible, and sometimes we use HEPA air filters to keep offending allergens and dust particles at bay.

20 Dec 2018

Novel ferrocenyl phosphines developed as potent antimalarial drugs

A team of researchers from the Singapore University of Technology and Design and Nanyang Technological University have developed novel ferrocene-based molecules that impair the malaria parasite's metabolic function leading to parasite death.

20 Dec 2018

Small Molecules News and Research

Scientists identify how cells make choice between various mechanisms to repair DNA

Novel Imaging Methods for Biomedicine

Researchers uncover how Gram-negative bacterium delivers toxins that make us sick

Study finds out similarity in function between healthy retina cell and tumor cell

New technique could expedite cancer diagnosis, lead to better patient outcomes

Scientists join forces to identify a new approach to fight African sleeping sickness

Mogrify to accelerate novel IP and cell therapies using $3.7m USD funding

Researchers uncover biochemical pathway that may help identify drugs to treat Alzheimer's

New therapeutic molecules show promise in reversing memory loss related to depression, aging

Pill that reverses brain damage could be on the horizon

Simple drug cocktail converts neighboring glial cells into functional new neurons

Expediting HPLC Method Development in Pharmaceutical Analysis

Scientists develop new gene therapy that prevents axon destruction in mice

Yeast model may pave way for development of novel therapies for metabolic disorders

Metabolite from berries and pomegranates can mitigate inflammatory bowel disease

Washington University scientists find an unknown route for cellular fuel delivery

Researchers develop mouse model to study consequences of fungal infection in the brain

New technique using microneedles may mean rapid diagnoses of major illnesses

New genetically modified common houseplant purifies air around it

Novel ferrocenyl phosphines developed as potent antimalarial drugs

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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