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Cancer Research Horizons: The Innovation Engine of Cancer Research UK

Following ELRIG 2022, News-Medical speaks with Cancer Research Horizons, the innovation engine of Cancer Research UK about their efforts to advance the drug discovery sector.

From Cancer Research UK 14 Nov 2022

Long-term humoral response and its determinants following 2- and 3-dose COVID-19 mRNA vaccines

Researchers compared the waning of vaccine-induced immunity from two and three doses of mRNA COVID-19 Pfizer-BioNTech vaccine BNT162b2 by conducting a repeated serological study to assess the prolonged humoral response.

14 Nov 2022

New UK aid will help fight AIDS, tuberculosis, and malaria

New UK aid support to the Global Fund will help fight AIDS, tuberculosis, and malaria around the world, Minister for Development Andrew Mitchell announced today (Monday 14 November).

14 Nov 2022

Reversing paralysis with electrical stimulation of neurons

In a recent study published in the Nature journal, researchers assessed the impact of spatiotemporal epidural electrical stimulation (EES) on individuals suffering from chronic spinal cord damage.

13 Nov 2022

Genicular nerve blocks provide short term pain relief for patients with knee osteoarthritis

Results from a recent clinical trial published by Wiley in Arthritis & Rheumatology demonstrate that patients with knee osteoarthritis experience short term pain relief from genicular nerve blocks - or locally injected anesthetics that block nerves around the knee joint.

13 Nov 2022

Popular dietary supplement linked to cancer risk, brain metastasis

Updated EULAR recommendations on the use of DMARDs for people with RA

Since their first publication in 2010, the EULAR recommendations for the use of disease-modifying anti-rheumatic treatments (DMARDs) in people with RA have become a most important publication in the field, and their updates are relied upon by many healthcare professionals, professional organizations and other stakeholders to offer an up-to-date and robust analysis on an optimal approach to the application of available treatment options in clinical practice.

11 Nov 2022

Study finds no differences in CAR T-cell therapy outcomes among pediatric ALL patients across different socioeconomic levels

Social determinants of health affect the outcomes of many illnesses, and pediatric cancer is no exception. In fact, children with acute lymphoblastic leukemia (ALL) living in poverty are significantly more likely to relapse and die from their disease than those from wealthier backgrounds.

11 Nov 2022

Mouth ulcer as first sign of monkeypox virus infection

Recent infection with monkeypox virus can initially present with very few pronounced clinical symptoms and lacking signs of infection, and only few skin vesicles may be visible.

11 Nov 2022

Study demonstrates immuno-based strategies to explore the treatment and prevention of COVID-19

Millions have died due to COVID-19 infection, and millions more continue experiencing the chronic condition, Long COVID, which makes discovering practical, accessible, and powerful SARS-CoV-2 preventatives and COVID-19 treatments essential.

11 Nov 2022

Study finds significant weight loss in residents of assisted living facilities during the COVID-19 quarantine

Older adults residing in assisted living facilities and quarantined to their rooms during the height of the COVID-19 pandemic lost significant weight, according to gerontology care providers and researchers from McGovern Medical School at UTHealth Houston.

11 Nov 2022

Delay in consciousness in severe cases of COVID-19 may be caused by neural hibernation

An article published in the journal PNAS provides a conceptual analysis to interpret the brain state of coronavirus disease 2019 (COVID-19) patients experiencing prolonged recovery of consciousness.

10 Nov 2022

IVI and Lemonex sign MOU to join forces on vaccine development

The International Vaccine Institute announced on November 10 it signed a memorandum of understanding (MOU) with Lemonex, a company specializing in RNA gene therapy development, and agreed to seek cooperation in research and development.

10 Nov 2022

Scientists validate safe surgical access to the central core of human cochlea

An international team of scientists and surgeons, including researchers from the University of Sheffield, has, for the first time, validated safe surgical access to the central core of the human cochlea.

10 Nov 2022

Study shows benefits of metastasis-directed therapy without ADT for oligorecurrent prostate cancer

For patients with solitary metastases from prostate cancer, an approach called metastasis-directed therapy (MDT) – focused treatment using surgery or radiation therapy, without androgen deprivation therapy (ADT) – can slow the time to cancer progression, reports a study in The Journal of Urology, an Official Journal of the American Urological Association

10 Nov 2022

New CRISPR approach is a leap forward in developing personalized treatment for cancer

For the first time, scientists have used CRISPR technology to insert genes that allow immune cells to focus their attack on cancer cells, potentially leaving normal cells unharmed and increasing the effectiveness of immunotherapy.

10 Nov 2022

Experimental therapeutic cancer vaccine leads to significant tumor regression in mice

An experimental therapeutic cancer vaccine induced two distinct and desirable immune system responses that led to significant tumor regression in mice, report investigators from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

10 Nov 2022

Research reveals why stem cell transplants are so successful in MS patients

Blood stem cell transplantation is a radical but highly effective therapy for multiple sclerosis. A study led by the University of Zurich has now examined in detail the way in which the treatment curbs the autoimmune disease and how the immune system regenerates afterwards.

10 Nov 2022

Duke scientists join team involved in the first use of fetal therapy for Pompe disease

Experts at Duke Health were among a multi-national team involved in treating a fetus for infantile-onset Pompe disease using an enzyme replacement therapy - a first in the world.

9 Nov 2022

Melatonin could be a potential therapy for long-COVID symptoms

A recent review published in the journal Biomolecules discussed the potential uses of melatonin in treating brain fog, and chronic fatigue syndrome or myalgic encephalomyelitis symptoms associated with long coronavirus disease (COVID)

9 Nov 2022

Therapy News and Research

Cancer Research Horizons: The Innovation Engine of Cancer Research UK

Long-term humoral response and its determinants following 2- and 3-dose COVID-19 mRNA vaccines

New UK aid will help fight AIDS, tuberculosis, and malaria

Reversing paralysis with electrical stimulation of neurons

Genicular nerve blocks provide short term pain relief for patients with knee osteoarthritis

Popular dietary supplement linked to cancer risk, brain metastasis

Updated EULAR recommendations on the use of DMARDs for people with RA

Study finds no differences in CAR T-cell therapy outcomes among pediatric ALL patients across different socioeconomic levels

Mouth ulcer as first sign of monkeypox virus infection

Study demonstrates immuno-based strategies to explore the treatment and prevention of COVID-19

Study finds significant weight loss in residents of assisted living facilities during the COVID-19 quarantine

Delay in consciousness in severe cases of COVID-19 may be caused by neural hibernation

IVI and Lemonex sign MOU to join forces on vaccine development

Scientists validate safe surgical access to the central core of human cochlea

Study shows benefits of metastasis-directed therapy without ADT for oligorecurrent prostate cancer

New CRISPR approach is a leap forward in developing personalized treatment for cancer

Experimental therapeutic cancer vaccine leads to significant tumor regression in mice

Research reveals why stem cell transplants are so successful in MS patients

Duke scientists join team involved in the first use of fetal therapy for Pompe disease

Melatonin could be a potential therapy for long-COVID symptoms

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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