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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

New research points to lncRNA's key role in helping control cellular processes

Scientific research over the past decade has concentrated almost exclusively on the 2 percent of the genome's protein coding regions, virtually ignoring the other 98 percent, a vast universe of non-coding genetic material previously dismissed as nothing more than 'junk.'

27 Dec 2016

CSHL researcher-inventor hails FDA approval of new SMA drug

Within a week of Christmas day, a drug called nusinersen will be in the hands of doctors across the nation, who will use it, most urgently, to treat young children with a severe and potentially fatal illness called spinal muscular atrophy (SMA).

26 Dec 2016

Ionis announces FDA approval of first SMA drug in the U.S for pediatric and adult patients

Ionis Pharmaceuticals, Inc. announced today that the U.S. Food and Drug Administration has approved SPINRAZATM (nusinersen) under Priority Review for the treatment of spinal muscular atrophy (SMA) in pediatric and adult patients.

26 Dec 2016

MDA celebrates FDA approval of new spinal muscular atrophy drug

The Muscular Dystrophy Association today celebrated news of the U.S. Food and Drug Administration's decision to grant approval for nusinersen (brand name Spinraza), the first disease-modifying drug to treat the most common genetic cause of death in infants.

23 Dec 2016

UC researchers uncover obesity-related protein's role in leukemia development

Cancer researchers at the University of Cincinnati College of Medicine have found an obesity-associated protein's role in leukemia development and drug response which could lead to more effective therapies for the illness.

22 Dec 2016

Mount Sinai researchers laying groundwork to find effective treatment for Zika virus

Researchers at the Icahn School of Medicine at Mount Sinai are working on the basic science that lays the groundwork to finding a way to treat and prevent the Zika virus, a global health risk.

22 Dec 2016

Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Diet-related diseases like non-alcoholic fatty liver disease (NAFLD) are known to have a major inflammatory component.

21 Dec 2016

Fly study shows RNA pathway plays major role in normal health and longevity

Humans and other animals carry rogue sequences of DNA in their genomes called transposable elements. To prevent passing TEs to their offspring, they employ the piRNA pathway in their reproductive organs to block the elements from being active in their sperm and eggs.

21 Dec 2016

Researchers creating computer model to track circadian clock

Biology dictates that DNA creates proteins which create - among other things - metabolites, the outputs of metabolism.

20 Dec 2016

TSRI scientists develop new methods to design precision medicines against disease-causing RNAs

Scientists on the Florida campus of The Scripps Research Institute have developed broad methods to design precision medicines against currently incurable diseases caused by RNA.

20 Dec 2016

Researchers use CRISPR-based genetic screening to identify three promising HIV treatment targets

Investigators from Whitehead Institute, the Ragon Institute of MGH, MIT and Harvard and the Broad Institute of MIT and Harvard have used CRISPR-Cas9 gene-editing technology to identify three promising new targets for treatment of HIV infection.

20 Dec 2016

Scientists develop novel nanoparticle-based method to deliver DNA vaccine

Scientists at Brigham and Women's Hospital have developed a novel method for delivering therapeutic molecules into cells.

20 Dec 2016

New ultrasensitive detection system of in-flow microRNAs uses encoded microgels

Single-stranded, noncoding micro-ribonucleic acids, consisting of 18-23 nucleotides, play a key role in regulating gene expression.

19 Dec 2016

Research finds link between p53 pathway and ribosome biogenesis, nucleotide metabolism in DBA

Diamond Blackfan Anemia (DBA) is a condition that is characterized by a failure of the bone marrow to produce red blood cells, congenital abnormalities, and a predisposition to cancer.

17 Dec 2016

Study provides new insights into fundamental characteristics of dendritic cells

Dendritic cells represent an important component of the immune system: they recognize and engulf invaders, which subsequently triggers a pathogen-specific immune response.

17 Dec 2016

Researchers find new insights into silencing of X-chromosomes in human embryos

Researchers have discovered new insights into how one of the two X-chromosomes is silenced during the development of female human embryos and also in lab-grown stem cells.

16 Dec 2016

Multifunctional RNA nanoparticles could overcome treatment resistance in breast cancer, study shows

Researchers at the University of Cincinnati College of Medicine have been able to generate multifunctional RNA nanoparticles that could overcome treatment resistance in breast cancer, potentially making existing treatments more effective in these patients.

15 Dec 2016

Porvair sciences introduce products for use in animal and plant genetics

Porvair Sciences will showcase two important technical breakthroughs at PAG XXV in San Diego (USA) from January 14-18, 2017.

From Chromatrap® - Porvair Sciences Ltd 15 Dec 2016

Oral cavity bacterium linked to development and progression of esophageal cancer

A type of bacterium usually found in the human mouth, Fusobacterium nucleatum, has been found to be related to the prognosis of esophageal cancer in Japanese patients by researchers from Kumamoto University, Japan.

9 Dec 2016

Researchers uncover first ‘off-switches’ for better control of CRISPR/Cas9 gene editing

CRISPR/Cas9 genome editing is quickly revolutionizing biomedical research, but the new technology is not yet exact. The technique can inadvertently make excessive or unwanted changes in the genome and create off-target mutations, limiting safety and efficacy in therapeutic applications.

9 Dec 2016

RNA News and Research

Further Reading

New research points to lncRNA's key role in helping control cellular processes

CSHL researcher-inventor hails FDA approval of new SMA drug

Ionis announces FDA approval of first SMA drug in the U.S for pediatric and adult patients

MDA celebrates FDA approval of new spinal muscular atrophy drug

UC researchers uncover obesity-related protein's role in leukemia development

Mount Sinai researchers laying groundwork to find effective treatment for Zika virus

Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Fly study shows RNA pathway plays major role in normal health and longevity

Researchers creating computer model to track circadian clock

TSRI scientists develop new methods to design precision medicines against disease-causing RNAs

Researchers use CRISPR-based genetic screening to identify three promising HIV treatment targets

Scientists develop novel nanoparticle-based method to deliver DNA vaccine

New ultrasensitive detection system of in-flow microRNAs uses encoded microgels

Research finds link between p53 pathway and ribosome biogenesis, nucleotide metabolism in DBA

Study provides new insights into fundamental characteristics of dendritic cells

Researchers find new insights into silencing of X-chromosomes in human embryos

Multifunctional RNA nanoparticles could overcome treatment resistance in breast cancer, study shows

Porvair sciences introduce products for use in animal and plant genetics

Oral cavity bacterium linked to development and progression of esophageal cancer

Researchers uncover first ‘off-switches’ for better control of CRISPR/Cas9 gene editing

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