Clinical Trial News and Research

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Adding a second HER2-targeted treatment may improve outcomes for some women with breast cancer

A phase III clinical trial of 4,805 women with HER2-positive breast cancer suggests adding a second HER2 targeted medicine, pertuzumab (Perjeta), to standard of care trastuzumab (Herceptin) after surgery may help, although the benefit is modest.

6 Jun 2017

Room sharing between babies and mothers linked to less sleep, unsafe sleeping practices

The American Academy of Pediatrics recommends parents keep babies in the same room with them to sleep for the first year to prevent sudden infant death syndrome.

5 Jun 2017

Findings point to potential new treatment for people with newly diagnosed EGFR-positive NSCLC

Findings from a phase III clinical trial point to a potential new treatment for patients newly diagnosed with advanced, epidermal growth factor receptor (EGFR)-positive non-small cell lung cancer (NSCLC).

5 Jun 2017

Novartis, Bristol-Myers Squibb collaborate to examine combination therapies for metastatic colorectal cancer

Novartis today announced it has entered into a clinical research collaboration in which Bristol-Myers Squibb will investigate the safety, tolerability, and efficacy of Mekinist (trametinib) in combination with Opdivo (nivolumab) and Opdivo + Yervoy (ipilimumab) regimen as a potential treatment option for metastatic colorectal cancer in patients with microsatellite stable tumors where the tumors are proficient in mismatch repair (MSS mCRC pMMR).

5 Jun 2017

Easy step enables people with type 1 diabetes to better regulate blood sugar levels

One additional injection of insulin three hours after eating has been shown to protect people with type 1 diabetes from cardiovascular disease - the leading cause of death among people with the condition.

5 Jun 2017

Single-dose radiotherapy effectively reduces spinal cord compression symptoms

A common complication in people with metastatic cancer, spinal cord compression is a major detriment to quality of life. Radiation treatment is widely used to relieve pain and other symptoms, but there is no standard recommended schedule, and approaches currently vary.

5 Jun 2017

Psychological intervention reduces fear of recurrence in breast cancer survivors

About 50% of all cancer survivors and 70% of young breast cancer survivors report moderate to high fear of recurrence.

5 Jun 2017

Novartis to collaborate with IBM Watson Health for improving outcomes in advanced breast cancer

Novartis today announced a first-of-its-kind collaboration with IBM Watson Health on an initiative to optimize cancer care and improve patient outcomes.

5 Jun 2017

Symptom self-reporting web-based tool could be used to help extend oncology patients' lives, study finds

The study funded by the Conquer Cancer Foundation of the American Society of Clinical Oncology (ASCO) has found that a simple intervention such as a web-based tool that facilitates patients to report their symptoms in real time, triggering alerts to clinicians, can have major benefits such as longer survival.

5 Jun 2017

Electronic patient-reported symptom monitoring increases survival compared with usual cancer care

The integration of electronic patient-reported outcomes into the routine care of patients with metastatic cancer was associated with increased survival compared with usual care, according to a study published by JAMA.

5 Jun 2017

Brief psychological intervention reduces depressive symptoms in patients with advanced cancer

Advanced cancer triggers enormous distress and brings challenges that can seem overwhelming. Yet, most cancer centers lack systematic approaches to help patients and families manage the practical and emotional toll of advanced cancer.

5 Jun 2017

Positive results for AstraZeneca’s PARP inhibitor Lynparza in advanced breast cancer

A new study has shown that AstraZeneca's Lynparza (olaparib) can significantly slow the progress of breast cancer that is caused partially due to mutations of the culprit gene called BRCA. BRCA gene mutations are responsible for around 3% of all breast cancers. These cases of the disease that have a basis in the gene are notoriously difficult to treat and women who are tested positive for this gene may even opt for removal of their breasts before even the cancer strikes. Noted actress Angelina Jolie went for a similar prophylactic mastectomy.

5 Jun 2017

New skin-adhesive diagnostic patch detects sleep apnea across all severity levels

Results of a definitive clinical trial show that a new, disposable diagnostic patch effectively detects obstructive sleep apnea across all severity levels.

5 Jun 2017

Standard therapy plus abiraterone lowers relative risk of death in men with advanced prostate cancer

A clinical trial of nearly 2,000 men shows that adding abiraterone acetate (Zytiga) to a standard initial treatment regimen for high-risk, advanced prostate cancer lowers the relative risk of death by 37%.

5 Jun 2017

Study provides reassurance to breast cancer survivors who contemplate pregnancy

Findings from a retrospective study of 1,200 women provide reassurance to breast cancer survivors who are contemplating pregnancy.

5 Jun 2017

Patients nearing end of life may not feel abandoned after discontinuation of cholesterol medications

New research suggests patients nearing the end of their lives because of a "life-limiting illness" such as cancer or heart disease may not feel medically abandoned if their doctor wants to take them off the statins that control their cholesterol.

2 Jun 2017

Genetic sequencing could help direct treatment for 72% of advanced cancer patients

A new analysis finds that nearly three-quarters of 500 patients with advanced cancer could be referred to a potential targeted treatment based on the results of a comprehensive analysis of their tumor's genetic landscape.

2 Jun 2017

Immunotherapy combination offers new hope for women with early stage triple negative breast cancer

A Yale Cancer Center clinical trial combining the immune checkpoint inhibitor (durvalumab/MEDI4736) with chemotherapy as preoperative treatment for early stage triple negative breast cancer disclosed a 71% pathologic complete response to the combination treatment in the initial phase I trial.

2 Jun 2017

BrainScope One study shows one-third potential reduction of avoidable CT scans in mild TBI patients

BrainScope Company, Inc. today announced a publication describing the use of its flagship product, BrainScope One, in an independent clinical trial demonstrating the potential reduction of one-third (33.3%) of unnecessary computed tomography scans of mildly presenting head injured patients in hospital emergency rooms.

2 Jun 2017

Early study of experimental vaccine shows escalating immune response in patients with sarcoma

The critical component of an experimental vaccine led to an escalating immune response in patients with sarcoma, an indicator of its potential anti-cancer effects.

2 Jun 2017

Clinical Trial News and Research

Adding a second HER2-targeted treatment may improve outcomes for some women with breast cancer

Room sharing between babies and mothers linked to less sleep, unsafe sleeping practices

Findings point to potential new treatment for people with newly diagnosed EGFR-positive NSCLC

Novartis, Bristol-Myers Squibb collaborate to examine combination therapies for metastatic colorectal cancer

Easy step enables people with type 1 diabetes to better regulate blood sugar levels

Single-dose radiotherapy effectively reduces spinal cord compression symptoms

Psychological intervention reduces fear of recurrence in breast cancer survivors

Novartis to collaborate with IBM Watson Health for improving outcomes in advanced breast cancer

Symptom self-reporting web-based tool could be used to help extend oncology patients' lives, study finds

Electronic patient-reported symptom monitoring increases survival compared with usual cancer care

Brief psychological intervention reduces depressive symptoms in patients with advanced cancer

Positive results for AstraZeneca’s PARP inhibitor Lynparza in advanced breast cancer

New skin-adhesive diagnostic patch detects sleep apnea across all severity levels

Standard therapy plus abiraterone lowers relative risk of death in men with advanced prostate cancer

Study provides reassurance to breast cancer survivors who contemplate pregnancy

Patients nearing end of life may not feel abandoned after discontinuation of cholesterol medications

Genetic sequencing could help direct treatment for 72% of advanced cancer patients

Immunotherapy combination offers new hope for women with early stage triple negative breast cancer

BrainScope One study shows one-third potential reduction of avoidable CT scans in mild TBI patients

Early study of experimental vaccine shows escalating immune response in patients with sarcoma

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