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Deep learning reveals genetic determinants of COVID-19-associated mortality

In a recent study posted to the medRxiv* preprint server, researchers applied deep learning methods and identified genetic variants linked to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-caused mortality.

11 May 2022

New initiative focuses on patients with the rarest of gene mutations to develop personalized ALS therapies

A new initiative, Silence ALS, will develop experimental personalized therapies to treat patients with rare genetic forms of ALS (also known as Lou Gehrig's disease).

10 May 2022

Decoy ACE2 nanoparticles block the entry of SARS-CoV-2 into cells

In a recent study posted to the bioRxiv* preprint server, researchers reported that nanoparticles could prevent severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) cell entry.

10 May 2022

Targeting the mitochondrial pathway may be a potential strategy to halt prostate cancer growth

Hormone therapy is often used to treat prostate cancer that has spread to other parts of the body, but many patients develop resistance to hormone therapy, causing their disease to become more aggressive and potentially more deadly.

10 May 2022

Deficiency of YWHAZ gene alters neurodevelopmental process in zebrafish

An article published in the journal Molecular Psychiatry reveals the molecular mechanisms to explain how the YWHAZ gene –related to psychiatric and neurological disorders such as autism and schizophrenia– can alter the neurodevelopmental process.

10 May 2022

Cancer cells in an acidic environment undergo lipid synthesis and accumulation, study shows

Alterations in metabolic processes are a hallmark of cancer and can lead to a tumor environment that is acidic. As a result, cancer cells must adapt to survive in this inhospitable environment.

10 May 2022

Cells do a little cleanup before mitosis

MIT researchers have discovered that before cells start to divide, they do a little cleanup, tossing out molecules that they appear not to need anymore.

10 May 2022

Using the “Wikiguideline” approach to improve the process for establishing medical guidelines

To improve the process for establishing medical guidelines, a group of international researchers are taking a new approach that leans on online collaboration and high-quality data.

10 May 2022

Fluorescent probe can track how tumors respond to drugs

Researchers say the fluorescent probe can track how tumours are responding to the drugs, which harness the body’s immune system to fight disease.

10 May 2022

Study finds link between hippocampal defects and intellectual disability in children with Joubert Syndrome

An important link has been found between the intellectual disability experienced by children with the rare disease Joubert Syndrome (JS) and defects in the hippocampus.

10 May 2022

Tumors release lactate to force neighboring cells into supporting cancer growth

Tumors can force neighboring cells into supporting cancer growth by releasing lactate into their local environment, according to researchers at Weill Cornell Medicine.

10 May 2022

AI model predicts postoperative recurrence of Crohn disease with high accuracy

Using an artificial intelligence (AI) tool that emulates how humans visualize and is trained to recognize and classify images, investigators constructed a model that predicts the postoperative recurrence of Crohn disease with high accuracy by evaluating histological images.

10 May 2022

Using virtual reality headsets to instruct UTSA students about protein structures

Francis Yoshimoto, assistant professor in the UTSA College of Sciences' Department of Chemistry, is introducing his Biochemistry II laboratory students to a new way of learning - using virtual reality headsets to observe and analyze protein structures.

10 May 2022

Lifesaving drug for opioid use disorder underutilized

Researchers at Washington University School of Medicine in St. Louis and Saint Louis University found that less than half of Americans who received treatment for opioid use disorder over a five-year period were offered a potentially lifesaving medication.

10 May 2022

Rigaku Announces Narcotics Interdiction Partnership Program to Help Reduce Deaths by Overdose

Rigaku Analytical Devices, a U.S.-based pioneer of handheld 1064 nm-Raman based spectrometers, is pleased to announce its new Human Infrastructure Health & Awareness (HIHA) Technology Narcotics Identification Partnership Program.

From Rigaku Analytical Devices 10 May 2022

Detecting treatments for autoimmune disease using an immune ‘fingerprint’

In this interview, we speak to Professor Joseph Powell about his latest research that investigated the use of immune 'fingerprints' to treat autoimmune disease.

10 May 2022

Remdesivir shows no significant effect on patients with COVID-19 in Solidarity trial

A recent study published in the journal The Lancet summarized the final results of the Solidarity trial which aimed at finding out which drugs were most effective at reducing the severity of the disease among hospitalized patients.

9 May 2022

Gene therapy effectively reduces neuropathic pain in mice with spinal cord injuries

An international team of researchers, led by scientists at University of California San Diego School of Medicine, report that a gene therapy that inhibits targeted nerve cell signaling effectively reduced neuropathic pain with no detectable side effects in mice with spinal cord or peripheral nerve injuries.

9 May 2022

Cancer mortality in sub-Saharan Africa could reach 1 million by 2030 without rapid interventions

Annual cancer deaths in sub-Saharan Africa (SSA) could reach 1 million by 2030, nearly double the 520,000 deaths from cancer that occurred in 2020.

9 May 2022

Q&A: COVID-19 pandemic has widened gender inequities in health

Health inequalities facing women and girls, already stark before the onset of COVID-19, have widened glaringly during the pandemic. Lockdowns restricted access to sexual and reproductive health services, increased violence against women, and interrupted girls’ education.

9 May 2022

Drugs News and Research

Deep learning reveals genetic determinants of COVID-19-associated mortality

New initiative focuses on patients with the rarest of gene mutations to develop personalized ALS therapies

Decoy ACE2 nanoparticles block the entry of SARS-CoV-2 into cells

Targeting the mitochondrial pathway may be a potential strategy to halt prostate cancer growth

Deficiency of YWHAZ gene alters neurodevelopmental process in zebrafish

Cancer cells in an acidic environment undergo lipid synthesis and accumulation, study shows

Cells do a little cleanup before mitosis

Using the “Wikiguideline” approach to improve the process for establishing medical guidelines

Fluorescent probe can track how tumors respond to drugs

Study finds link between hippocampal defects and intellectual disability in children with Joubert Syndrome

Tumors release lactate to force neighboring cells into supporting cancer growth

AI model predicts postoperative recurrence of Crohn disease with high accuracy

Using virtual reality headsets to instruct UTSA students about protein structures

Lifesaving drug for opioid use disorder underutilized

Rigaku Announces Narcotics Interdiction Partnership Program to Help Reduce Deaths by Overdose

Detecting treatments for autoimmune disease using an immune ‘fingerprint’

Remdesivir shows no significant effect on patients with COVID-19 in Solidarity trial

Gene therapy effectively reduces neuropathic pain in mice with spinal cord injuries

Cancer mortality in sub-Saharan Africa could reach 1 million by 2030 without rapid interventions

Q&A: COVID-19 pandemic has widened gender inequities in health

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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