Tumor News and Research

RSS

Pembrolizumab provides added benefit for subpopulations of patients with metastatic NSCLC

In early July, the German Institute for Quality and Efficiency in Health Care conducted two early benefit assessments to investigate whether certain drug combinations with pembrolizumab have advantages in comparison with the respective appropriate comparator therapy for patients with metastatic squamous or non-squamous non-small cell lung cancer.

20 Sep 2019

New prediction models for improved treatment of lymph nodes in breast cancer patients

In recently published studies, researchers at Lund University and Skåne University Hospital in Sweden have produced new prediction models for improved personalized treatment of lymph nodes in breast cancer patients.

20 Sep 2019

Scientists identify pathway for treatment-resistant lung cancer

A big way chemotherapy works is by prompting cancer cells to commit suicide, and scientists have found a pathway the most common lung cancer walks to avoid death.

20 Sep 2019

Discovery of combination protein leads to first-in-human clinical trial for leukemia

The discovery of tri-specific natural killer engagers (TriKE™), a combination protein that bridges an immune cell and a tumor cell to drive tumor cell killing power exponentially, has led to a new Phase I, first-in-human study to treat leukemia.

20 Sep 2019

Whole-brain radiotherapy recommended for patients with brain metastases

Patients with brain metastases who received whole-brain radiotherapy that avoided memory-specific hippocampal neural stem cells experienced preserved cognitive function and reported fewer neurologic symptoms and better cognition over time, according to results from an NRG Oncology clinical trial presented Sept. 15, 2019 at the American Society for Radiation Oncology Annual Meeting in Chicago.

20 Sep 2019

Mitochondrial fission factor could represent a promising target for cancer therapy

Researchers at The Wistar Institute have described the role of mitochondrial fission factor (MFF) in controlling survival of cancer cells, suggesting the protein could represent a promising therapeutic target. They also found that expression of MFF is regulated by Myc, a ubiquitous mediator of cell proliferation that contributes to development of many cancer types.

20 Sep 2019

Researchers describe how neurons establish contact with aggressive glioblastomas, promote tumor growth

In a current paper published in the journal "Nature", Heidelberg-based researchers and physicians describe how neurons in the brain establish contact with aggressive glioblastomas and thus promote tumor growth / New tumor activation mechanism provides starting points for clinical trials

20 Sep 2019

Research: Metformin may be effective in treating breast cancer that lacks Nischarin protein

Research conducted by Suresh Alahari, PhD, Professor of Biochemistry and Genetics at LSU Health New Orleans School of Medicine, has found that metformin, a commonly prescribed drug for Type 2 Diabetes, may be effective in treating cancers that lack a protein called Nischarin.

20 Sep 2019

Anti-cancer protein promotes tumor resistance, shows study

Areas of solid tumors that have limited access to oxygen, a condition called hypoxia, are highly resilient against chemo and radiation therapy.

20 Sep 2019

Brain tumors hijack healthy neurons in order to grow

Scientists have discovered that brain tumors integrate themselves with the brain’s healthy neuronal network to support their growth.

19 Sep 2019

Researchers discover how cancer cells can trigger chronic muscle wasting condition

A solid tumor can cause muscle cells in the body to self-destruct. Many cancer patients die from the consequences. Now researchers are discovering more about how cancer cells in a tumor can take control of muscle cell wasting and trigger a chronic, serious condition.

19 Sep 2019

Study uncovers new factor in the development of childhood lymphoma

A study recently published in the renowned journal Blood, led by Kaan Boztug, Scientific Director of the St. Anna Children's Cancer Research Institute, the Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Adjunct Principal Investigator at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and Associate Professor at the Medical University of Vienna, together with scientists from Israel, Germany, Turkey, Colombia, Argentina and the USA, investigated four patients from independent families with malignancy, autoimmunity and immunodeficiency.

19 Sep 2019

Using 3D virtual reality models to prepare for surgeries improves patient outcomes

A UCLA-led study has found that using three-dimensional virtual reality models to prepare for kidney tumor surgeries resulted in substantial improvements, including shorter operating times, less blood loss during surgery and a shorter stay in the hospital afterward.

19 Sep 2019

Microrna-based therapy may prove to be effective against chemotherapy-resistant cancers

A technology that manipulates microRNAs developed by Jingfang Ju, PhD, a biochemist and Professor in the Department of Pathology at the Renaissance School of Medicine at Stony Brook University, and colleagues has shown promise when used as anti-cancer therapeutic.

19 Sep 2019

Study opens a promising new front in the fight against pancreatic cancer

Pancreatic adenocarcinoma (PDAC) is a lethal malignancy that most often is resistant to chemotherapy. Researchers have been searching for ways to increase the sensitivity of the tumors to cancer-fighting drugs.

19 Sep 2019

NMDAR receptor is responsible for breast-to-brain metastases, shows study

In 2018, breast cancer was the most common cancer in women worldwide, accounting for about a quarter of all reported cancers. One of the biggest problems with any type of cancer is metastasis; and when breast cancer metastasizes, the brain is a common destination.

19 Sep 2019

New 'Idiopathic Anaphylaxis Yardstick' offers guidance for diagnosis and treatment

Many people in danger of the severe allergic reaction known as anaphylaxis understand exactly what they need to avoid to stay safe.

18 Sep 2019

Roswell Park moving three-pronged immunotherapy strategy forward with support from DoD grant

A team from Roswell Park Comprehensive Cancer Center is moving a new three-part strategy for treating advanced cancers forward with support from a U.S. Department of Defense grant to Pawel Kalinski, MD, PhD, Vice Chair for Translational Research and Rustum Family Professor for Molecular Therapeutics and Translational Research at the Buffalo, N.Y.-based cancer center.

18 Sep 2019

NUS chemists develop new anti-cancer drug with less renal toxicity

A team of pharmacists and chemists from the National University of Singapore has developed a new anti-cancer drug that has less toxic effects to the kidneys.

18 Sep 2019

Compound could play a novel role in halting spread of pancreatic cancer

In early test tube and mouse studies, investigators at Johns Hopkins Medicine and the Johns Hopkins Kimmel Cancer Center have found that nonmuscle myosin IIC (MYH14), a protein activated in response to mechanical stress, helps promote metastatic behavior in pancreatic cancer cells, and that the compound 4-hydroxyacetophenone (4-HAP), known to stiffen myosin IIC-containing cells, can send it into overdrive, overwhelming the ability of cells to invade nearby tissue.

18 Sep 2019

Tumor News and Research

Pembrolizumab provides added benefit for subpopulations of patients with metastatic NSCLC

New prediction models for improved treatment of lymph nodes in breast cancer patients

Scientists identify pathway for treatment-resistant lung cancer

Discovery of combination protein leads to first-in-human clinical trial for leukemia

Whole-brain radiotherapy recommended for patients with brain metastases

Mitochondrial fission factor could represent a promising target for cancer therapy

Researchers describe how neurons establish contact with aggressive glioblastomas, promote tumor growth

Research: Metformin may be effective in treating breast cancer that lacks Nischarin protein

Anti-cancer protein promotes tumor resistance, shows study

Brain tumors hijack healthy neurons in order to grow

Researchers discover how cancer cells can trigger chronic muscle wasting condition

Study uncovers new factor in the development of childhood lymphoma

Using 3D virtual reality models to prepare for surgeries improves patient outcomes

Microrna-based therapy may prove to be effective against chemotherapy-resistant cancers

Study opens a promising new front in the fight against pancreatic cancer

NMDAR receptor is responsible for breast-to-brain metastases, shows study

New 'Idiopathic Anaphylaxis Yardstick' offers guidance for diagnosis and treatment

Roswell Park moving three-pronged immunotherapy strategy forward with support from DoD grant

NUS chemists develop new anti-cancer drug with less renal toxicity

Compound could play a novel role in halting spread of pancreatic cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News