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Novel drug target may help overcome resistance to EZH2 inhibitors in SMARCB1 mutated cancers

Inhibitors of the protein EZH2 are effective against cancers with SMARCB1 mutations such as rhabdoid tumors in children.

9 May 2022

New genetic markers could improve early detection of drug-resistant tuberculosis

To many, tuberculosis (TB) may seem like a disease from a bygone era. But it still claims more than one million lives every year.

9 May 2022

Researchers make breakthrough in overcoming drug resistance in a rare, devastating blood cancer

South Australian scientists have made a significant breakthrough in overcoming drug resistance in acute myeloid leukemia (AML), a rare and devastating blood cancer that kills most patients within a few years.

9 May 2022

Single-cell genomic sequencing identifies a subpopulation of human dopamine neurons that degenerates in Parkinson’s disease

Researchers developed a novel protocol to examine dopamine (DA) neurons extracted from Parkinson’s disease (PD) patients using single-cell genomic sequencing.

9 May 2022

How new Insights into ESR1 Mutant Breast Cancers may lead to Novel Therapy Targets

In this interview, we speak to Steffi Oesterreich, PH.D., from the University of Pittsburgh, about how new insights into a gene mutation present in 20-30% of breast cancer recurrences may have a silver lining, leading to novel treatment opportunities.

9 May 2022

Evaluating the Role of Automated LabTech Instruments within Research

In this interview, we speak to Günter Tenzler, founder and CEO of INHECO, about their automated labtech instruments and their role within scientific research.

From Society for Laboratory Automation and Screening (SLAS) 9 May 2022

Mailed at-home disposal kits increase disposal rates of unused opioids after surgery

Mailed opioid disposal kits led to 60 percent of patients who had leftover opioid pain pills properly disposing of them after surgeries, according to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania.

6 May 2022

Newly-discovered mechanism may help prevent the build-up toxic proteins in dementia

It's often said that a little stress can be good for you. Now scientists have shown that the same may be true for cells, uncovering a newly-discovered mechanism that might help prevent the build-up of tangles of proteins commonly seen in dementia.

6 May 2022

Study reveals why some lungs are protected against COVID

COVID-19 vaccines have saved at least a million lives in the United States alone, but for many people, a lingering fear remains: if - or when - they get hit by the coronavirus, just how bad will it be? Will they breeze through with little more than a sore throat - or will it saddle them with long-term complications, perhaps even push them to the brink of death?

6 May 2022

Potential antiviral targets in SARS-CoV-2

Researchers assessed potential targets in severe acute respiratory syndrome coronavirus 2.

6 May 2022

Applying a form of AI to sift through large amounts of biological data

Researchers at the University of Missouri are applying a form of artificial intelligence (AI) - previously used to analyze how National Basketball Association (NBA) players move their bodies - to now help scientists develop new drug therapies for medical treatments targeting cancers and other diseases.

6 May 2022

Marine bioactive compounds against SARS-CoV-2

A new review paper published in the journal Environmental Science and Pollution Research aimed to determine the possibilities of using biologically active compounds derived from various chemical classes of marine organisms against SARS-CoV-2 infection at various stages of the life cycle of the virus.

6 May 2022

Drugs News and Research

Novel drug target may help overcome resistance to EZH2 inhibitors in SMARCB1 mutated cancers

New genetic markers could improve early detection of drug-resistant tuberculosis

Researchers make breakthrough in overcoming drug resistance in a rare, devastating blood cancer

Single-cell genomic sequencing identifies a subpopulation of human dopamine neurons that degenerates in Parkinson’s disease

How new Insights into ESR1 Mutant Breast Cancers may lead to Novel Therapy Targets

Evaluating the Role of Automated LabTech Instruments within Research

Mailed at-home disposal kits increase disposal rates of unused opioids after surgery

Newly-discovered mechanism may help prevent the build-up toxic proteins in dementia

Study reveals why some lungs are protected against COVID

Potential antiviral targets in SARS-CoV-2

Applying a form of AI to sift through large amounts of biological data

Marine bioactive compounds against SARS-CoV-2

Stem cell therapy prevents type 1 diabetes induced by anti-cancer drugs

Reduced-calorie diet plus time-restricted eating promote longevity in mice

KHN’s ‘What the Health?’: Leaked abortion opinion rocks Washington’s world

Combination of certain drugs along with ibuprofen can cause acute kidney injury

Evaluation of the potential of new and repurposed TB vaccines

New model can predict drug-drug interactions based on drug-induced gene expression signatures

Hypertonic saline solution enhances glymphatic spinal cord delivery of pharmaceutical agents

Study identifies a protein in Mycobacterium tuberculosis that contributes to drug tolerance

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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