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New combination therapy found to be well tolerated in patients with aggressive brain tumor

A phase I clinical trial that set out to assess the safety of a new combination therapy for a type of aggressive brain tumour has found the treatment to be well tolerated in patients.

30 Mar 2019

Designer organelles in living mammalian cells can build synthetic proteins

A research team led by biophysical chemist Professor Edward Lemke has engineered a designer organelle in a living mammalian cell in a new complex biological translation process. The created membraneless organelle can build proteins from natural and synthetic amino acids carrying new functionalities.

30 Mar 2019

Scientists create new models of tropical eye worm for development of anti-filarial drugs

Researchers at the LSTM's Centre for Drugs and Diagnostics, and University of Buea, Cameroon have developed new models of the tropical eye worm, Loa loa for the development of new drugs against filariasis.

30 Mar 2019

Researchers produce first global map of cerebral function lateralization

In 1865, French physician Paul Broca noted that among patients with brain damage, only those with the left frontal lobe affected had speech difficulties.

30 Mar 2019

Preterm babies born without a protein in blood cells have higher risk of cerebral palsy and death

Researchers at the University of Illinois at Chicago have found that some preterm babies born without haptoglobin, a protein in blood cells, have higher odds of brain bleeding, cerebral palsy and death. Their findings suggest that the absence of the protein could serve as a potential biomarker indicating a need for increased monitoring or other preventive interventions.

30 Mar 2019

Study highlights need to diversify population-level genetic data for better disease prediction

Polygenic scores can predict a person's risk for conditions like coronary artery disease, breast cancer, and type 2 diabetes (T2D) with great accuracy, even in patients who lack common warning signs. This new genome analysis tool holds promise for physicians, who may be able to intervene earlier to help prevent common disease for at-risk individuals.

30 Mar 2019

Cellular mechanism that connects smoking during pregnancy and baby’s obesity risk identified

Using foreskin tissue from newborn circumcisions, a group of researchers have identified a potential cellular mechanism that connects a mother's smoking while pregnant with an increased risk of offspring obesity later in life.

30 Mar 2019

Bruker acquires cloud-based scientific software provider Arxspan

Bruker Corporation today announced that it has acquired Arxspan LLC, a provider of cloud-based scientific software and workflow solutions, based in Southborough, Massachusetts.

From Bruker BioSpin Division 30 Mar 2019

IASLC 2019 Small Cell Lung Cancer Meeting focuses on immunotherapy and patient perspective

While non-small cell lung cancer is the more common form of lung cancer and attracts the lion's share of the research funding, recent developments in small cell lung cancer may be shifting that slightly.

29 Mar 2019

Educating doctors alone may not have a noticeable effect on prescribing rates, study shows

Purely educating doctors about the importance of prescribing certain therapies may not be enough to make a meaningful impact, according to a new Penn Medicine study.

29 Mar 2019

UA immunobiology professor will use $1.9 million grant to study copper's therapeutic potential

Pneumonia starts like this: A bacterial cell called Streptococcus pneumoniae enters the nostril. It travels down the nasal passage and into the lungs, where a war begins. In the lungs, S. pneumoniae encounters immune cells called macrophages, which will do whatever they can to fight it off.

29 Mar 2019

New Hasso Plattner Institute for Digital Health launched at Mount Sinai

The Mount Sinai Health System and the Hasso Plattner Institute today announced an affiliation that brings together industry leaders with combined expertise in health care delivery, health sciences, biomedical and digital engineering, machine learning and artificial intelligence to rapidly develop digital health products with real-time predictive and preventive capabilities that empower patients and health care providers, and improve health and health outcomes.

29 Mar 2019

Gastrointestinal symptoms in children could be a red flag for future mental health problems

A Columbia University study has found that adversity early in life is associated with increased gastrointestinal symptoms in children that may have an impact on the brain and behavior as they grow to maturity.

29 Mar 2019

FDA approves new oral drug to treat relapsing forms of multiple sclerosis

The U.S. Food and Drug Administration today approved Mavenclad (cladribine) tablets to treat relapsing forms of multiple sclerosis (MS) in adults, to include relapsing-remitting disease and active secondary progressive disease.

29 Mar 2019

CMS ignores federal judge ruling to approve Medicaid work rules in Utah

Less than 48 hours after a federal judge struck down Medicaid work requirements, the Centers for Medicare & Medicaid Services on Friday gave Utah permission to use those mandates.

29 Mar 2019

Maternal smoking and pre-eclampsia may affect fertility of offspring

Low levels of oxygen in the womb - which can be caused by smoking or conditions such as pre-eclampsia - may cause problems with fertility later in life, a study carried out in rats suggests.

29 Mar 2019

Study finds two new genes in the developmental defects of canine enamel

In addition to humans, hereditary disorders of enamel development occur in dogs, greatly impacting their dental health and wellbeing. A recent study reveals canine enamel disorders similar to those found in humans, linking them with ENAM and ACP4, two genes previously described in humans.

29 Mar 2019

New approach to delivering school-based vaccines improves student's experience

Researchers at the University of Toronto and The Hospital for Sick Children (SickKids) have teamed up with educators, public health practitioners and grade seven students in Ontario to develop and implement a new approach to delivering school-based vaccines that improves student experience.

29 Mar 2019

APS-ASPET Presidential Symposium Series spotlights advances in gut microbiome research

Leading physiology and pharmacology researchers will speak in a four-part series centered on the gut microbiome--the microbe population living in the digestive tract--and its role in wound recovery, hypertension and nervous system function.

29 Mar 2019

Scientists identify two, extremely rare genetic variants linked to Alzheimer disease

Researchers have identified two, extremely rare genetic variants linked to Alzheimer disease (AD) for the first time.

29 Mar 2019

Research News and Research

New combination therapy found to be well tolerated in patients with aggressive brain tumor

Designer organelles in living mammalian cells can build synthetic proteins

Scientists create new models of tropical eye worm for development of anti-filarial drugs

Researchers produce first global map of cerebral function lateralization

Preterm babies born without a protein in blood cells have higher risk of cerebral palsy and death

Study highlights need to diversify population-level genetic data for better disease prediction

Cellular mechanism that connects smoking during pregnancy and baby’s obesity risk identified

Bruker acquires cloud-based scientific software provider Arxspan

IASLC 2019 Small Cell Lung Cancer Meeting focuses on immunotherapy and patient perspective

Educating doctors alone may not have a noticeable effect on prescribing rates, study shows

UA immunobiology professor will use $1.9 million grant to study copper's therapeutic potential

New Hasso Plattner Institute for Digital Health launched at Mount Sinai

Gastrointestinal symptoms in children could be a red flag for future mental health problems

FDA approves new oral drug to treat relapsing forms of multiple sclerosis

CMS ignores federal judge ruling to approve Medicaid work rules in Utah

Maternal smoking and pre-eclampsia may affect fertility of offspring

Study finds two new genes in the developmental defects of canine enamel

New approach to delivering school-based vaccines improves student's experience

APS-ASPET Presidential Symposium Series spotlights advances in gut microbiome research

Scientists identify two, extremely rare genetic variants linked to Alzheimer disease

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