Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

International consortium to get to heart of coronary artery disease

An international consortium has been launched to tackle coronary artery disease using the latest scientific tools. Funded by the European Commission, the initiative will build on recent advances in genomic science and the understanding of our genes to develop effective strategies for preventing and treating the disease.

7 Feb 2007

Risk of developing diabetes increasingly involved in decisions regarding HRT

Although doctors for years have "talked about the health effects of hormones on bones, breasts and women's hearts," diabetes has not been "part of the debate" until last week, when the North American Menopause Society in a revised position statement said that women taking hormone replacement therapy appear to be less likely to develop the disease, the Wall Street Journal reports.

7 Feb 2007

Power-boosting signal in muscle declines with age

As people age, they may have to exercise even harder to get the benefits afforded to younger folk. That's the suggestion of a report in the February issue of the journal Cell Metabolism, showing that a signal that gives muscles a kind of metabolic boost in response to exercise is blunted in older animals.

6 Feb 2007

Discovery of pancreatic cancer stem cells could lead to more effective therapies

Scientists in the United States have identified for the first time the stem cells linked to pancreatic cancer.

1 Feb 2007

Cruelty-free ELISA for human insulin

In the January issue of Clinical Biochemistry, scientists and physicians with the Physicians Committee for Responsible Medicine (PCRM) outline the method used to develop a cruelty-free ELISA for human insulin that uses monoclonal antibodies produced by cells cultured in an animal-serum-free medium.

30 Jan 2007

Weight loss supplement - conjugated linoleic acid - shows nasty side effects

A supplement some people turn to in hopes of losing a few pounds may have some previously unknown, unsavory side effects, suggest two new studies.

30 Jan 2007

SH2B1 protein plays a key role in controlling body weight, response to insulin and leptin

A single protein in brain cells may act as a linchpin in the body's weight-regulating system, playing a key role in the flurry of signals that govern fat storage, sugar use, energy balance and weight, University of Michigan Medical School researchers report.

29 Jan 2007

Healthy 4 year-olds who eat lots of fat weigh less

Four-year-olds eat too few vegetables and too much sugar. They also bolt down lots of junk food, but children who eat more fat than others nevertheless weigh less. This is shown in a new dissertation from the Sahlgrenska Academy at Goteborg University in Sweden.

28 Jan 2007

Melanin concentrating hormone found to be involved with insulin production

A new Joslin Diabetes Center-led study has shown conclusively that a neuropeptide, melanin concentrating hormone (MCH), found in the brain and known for its role in increasing appetite in people, plays a role in the growth of insulin-producing beta cells and the secretion of insulin.

28 Jan 2007

Using fibre in the fight against breast cancer

Wholemeal bread and wholegrain cereal could be key weapons in the battle against breast cancer.

24 Jan 2007

Lilly to change global manufacturing operations

Eli Lilly and Company has announced several strategic changes to its global manufacturing operations to better support the company's current product portfolio and evolving drug pipeline.

14 Jan 2007

Major variations in Medicare drug costs

Soon, Congress may vote on whether to require the Medicare system to negotiate lower prices for medicines taken by millions of seniors enrolled in Medicare Part D prescription drug plans.

10 Jan 2007

Allergic reactions to insulin have declined and Continuous Subcutaneous Insulin Infusion could reduce them further

A review of published research from the University of Liege, Belgium, reveals a decline in the number of people experiencing allergic reactions to insulin. This is largely due to better purification of animal insulin and the introduction of human recombinant insulin.

8 Jan 2007

High uric acid levels indicate risk for cognitive problems in old age

Researchers at the Johns Hopkins and Yale university medical schools have found that a simple blood test to measure uric acid, a measure of kidney function, might reveal a risk factor for cognitive problems in old age.

2 Jan 2007

Cytogen issued new patent covering oral drug delivery agents

Cytogen Corporation has announced that it has been issued United States patent number 7,135,457 covering its oral drug delivery agents - random peptide compositions that bind to gastro-intestinal tract (GIT) transport receptors.

28 Nov 2006

Researchers identify risk factors for healthy survival in men

Avoiding health risk factors in midlife such as smoking, being overweight, excessive drinking and hypertension is associated with a longer and healthier life in men, according to a study in the November 15 issue of JAMA: The Journal of the American Medical Association, a theme issue on men's health.

14 Nov 2006

Pioglitazone may help slow progression of artery wall thickening

A medication given to diabetics to improve their body's sensitivity to insulin also appears to slow the thickening of their artery walls, according to a study posted online by JAMA: The Journal of the American Medical Association.

13 Nov 2006

Thiazolidinediones may reduce cardiovascular risks

A drug commonly used to increase the body's sensitivity to insulin may slow the progression of cardiovascular disease in patients with type 2 diabetes, according to a study at the University of Illinois at Chicago College of Medicine.

13 Nov 2006

Lots of sweet food and drink increases risk of pancreatic cancer

Pancreatic cancer is a very serious form of cancer that is possibly caused when the pancreas produces heightened levels of insulin as a consequence of upset glucose metabolism. A well-known way of increasing insulin production is to eat a lot of sugar.

8 Nov 2006

Which works best in fighting the risk factors for diabetes - exercise or diet?

It's a toss up, according to a new study by a Saint Louis University researcher who is a member of a Washington University team of scientists examining whether a calorie-restrictive diet can extend people's lifespan.

8 Nov 2006