Infectious Diseases News and Research

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Low dose injections of artificial properdin provide protection against septic diseases

Researchers at the University of Leicester have produced an artificial version of a naturally occurring protein, properdin, which has been found to successfully combat bacterial pneumonia and meningitis when tested in mice.

25 Mar 2014

IDRI awarded grant extension of $3.4M for identifying new leads and drug targets for tuberculosis

IDRI's drug discovery efforts continue to grow with a recently awarded grant extension of $3.4 million from the Bill & Melinda Gates Foundation. The additional funding was awarded to Tanya Parish, Ph.D., IDRI's Vice President of Drug Discovery, and supplements an earlier grant awarded in 2010, for a total of $7.8 million.

25 Mar 2014

Tuberculosis control needs a complete and patient-centric solution

Whether it is mobile phone service or vacation travel, good businesses know that success depends on providing a complete and customer-centric solution. Should patients with tuberculosis not be offered a complete solution that is patient-centered? After all, millions are affected and a large market at the base-of-the-pyramid (BoP) remains unserved.

24 Mar 2014

Drugs fail to "wake up" dormant reservoirs of HIV inside immune system T cells

Scientists at Johns Hopkins report that compounds they hoped would "wake up" dormant reservoirs of HIV inside immune system T cells - a strategy designed to reverse latency and make the cells vulnerable to destruction - have failed to do so in laboratory tests of such white blood cells taken directly from patients infected with HIV.

24 Mar 2014

Russian Ministry of Health approves Medivir's simeprevir for chronic hepatitis C genotype 1 infection

Medivir AB announced today that the Russian Ministry of Health has approved Sovriad (simeprevir) for the treatment of chronic hepatitis C genotype 1 infection, in combination with peginterferon alfa and ribavirin, in adults with compensated liver disease (including cirrhosis) who are treatment naïve or who have failed previous interferon therapy (pegylated or non-pegylated) with or without ribavirin. Russia will be the first country within EMEA to gain access to simeprevir, which represents a significant advance in hepatitis C treatment.

24 Mar 2014

New national research consortium focuses on better drug therapies for viral infections

Viral infections with limited or no treatment options can pose a major global health threat, but a new national research consortium centered at the University of Alabama at Birmingham is focused on the discovery of new and better drug therapies as these viruses emerge.

24 Mar 2014

Researchers find immune receptor for uric acid crystals

The surface of immune system cells is home to a number of receptors which are able to detect pathogens. As soon as these receptors are activated, inflammation occurs and the body's defense mechanisms kick in. Immune cells also have receptors that regulate or even suppress immunological responses to prevent damage to individual cells.

21 Mar 2014

Tetraphase provides clinical update on lead antibiotic candidate and Phase 3 clinical program

Tetraphase Pharmaceuticals, Inc. (NASDAQ:TTPH) today provided a clinical update on its lead antibiotic candidate, eravacycline, and its Phase 3 global clinical program IGNITE (Investigating Gram-negative Infections Treated with Eravacycline).

21 Mar 2014

NIH awarded five-year grant of up to $28 million to fight deadly Ebola virus

The National Institutes of Health (NIH) has awarded a five-year grant of up to $28 million to establish a new center for excellence to find an antibody "cocktail" to fight the deadly Ebola virus.

21 Mar 2014

NIH awards $28M grant to establish new center for excellence to find treatment for Ebola virus

The National Institutes of Health has awarded a five-year, $28 million grant to establish a new center for excellence to find an antibody "cocktail" to fight two types of viruses that cause severe hemorrhagic fever, including the deadly Ebola virus. The project involves researchers from 15 institutions, including Kartik Chandran, Ph.D., and Jonathan Lai, Ph.D., at Albert Einstein College of Medicine of Yeshiva University. Einstein will receive approximately $4 million of the total grant.

21 Mar 2014

GHIT Fund announces grants to speed up innovative drug development for neglected diseases

The Global Health Innovative Technology Fund, a new public health partnership that is bringing Japanese know-how and investment to the global fight against infectious diseases, today announced three grants worth a total of US$6.8 million to speed the development of innovative drugs for some of the world’s most neglected diseases—schistosomiasis, Chagas disease and parasitic roundworms.

20 Mar 2014

New study provides first ever reliable data on antibiotic use in non-EU countries

A new study, published in The Lancet Infectious Diseases journal, provides the first ever reliable data on antibiotic use in non-European Union southern and eastern European countries and newly independent states.

20 Mar 2014

Scientist receives $147,157 grant from NIH to find cure for infectious disease

A Clemson University scientist was awarded a two-year, $147,157 grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, to find a cure for an infectious disease.

20 Mar 2014

Preterm babies' guts harbor infectious microbes that can cause late-onset sepsis

Babies born prematurely are surviving in increasing numbers. But many withstand complications of early birth only to suffer late-onset sepsis - life-threatening bloodstream infections that strike after infants reach 72 hours of age.

20 Mar 2014

Study: Infections caused by antibiotic-resistant bacteria are on rise in U.S. children

Infections caused by a concerning type of antibiotic-resistant bacteria are on the rise in U.S. children, according to a new study published in the Journal of the Pediatric Infectious Diseases Society and available online.

20 Mar 2014

Scientists describe gut bacteria that cause sepsis in preterm infants

Researchers studying intestinal bacteria in newborns have characterized the gut bacteria of premature infants who go on to develop sepsis, a serious and potentially life-threatening condition caused by bacteria in the bloodstream.

19 Mar 2014

Many community hospitals prescribe ineffective antibiotics for patients with bloodstream infections

Growing drug resistance, a high prevalence of S. aureus bacteria and ineffective antibiotics prescribed to one in three patients are among the challenges facing community hospitals in treating patients with serious bloodstream infections, according to researchers at Duke Medicine.

19 Mar 2014

USTAR Center for Genetic Discovery to integrate genome data with patient care

The USTAR Center for Genetic Discovery is partnering with California based Omicia, Inc, to make analyzing a patient's genome as routine as performing a blood test.

19 Mar 2014

UCLA creates new program that helps adoptive parents, children navigate through international adoption process

With thousands of internationally adopted children arriving in the United States each year, there is a growing demand for a specialized health-care support system that helps adoptive parents and children navigate through the international adoption process.

19 Mar 2014

Medivir announces phase III ATTAIN study of simeprevir inhibitor in treatment of adult patients with HCV

Medivir AB today announced that new phase III data for the once-daily protease inhibitor simeprevir have been presented at the Conference of the Asian Pacific Association for the Study of the Liver (APASL) in Brisbane, Australia.

19 Mar 2014

Infectious Diseases News and Research

Low dose injections of artificial properdin provide protection against septic diseases

IDRI awarded grant extension of $3.4M for identifying new leads and drug targets for tuberculosis

Tuberculosis control needs a complete and patient-centric solution

Drugs fail to "wake up" dormant reservoirs of HIV inside immune system T cells

Russian Ministry of Health approves Medivir's simeprevir for chronic hepatitis C genotype 1 infection

New national research consortium focuses on better drug therapies for viral infections

Researchers find immune receptor for uric acid crystals

Tetraphase provides clinical update on lead antibiotic candidate and Phase 3 clinical program

NIH awarded five-year grant of up to $28 million to fight deadly Ebola virus

NIH awards $28M grant to establish new center for excellence to find treatment for Ebola virus

GHIT Fund announces grants to speed up innovative drug development for neglected diseases

New study provides first ever reliable data on antibiotic use in non-EU countries

Scientist receives $147,157 grant from NIH to find cure for infectious disease

Preterm babies' guts harbor infectious microbes that can cause late-onset sepsis

Study: Infections caused by antibiotic-resistant bacteria are on rise in U.S. children

Scientists describe gut bacteria that cause sepsis in preterm infants

Many community hospitals prescribe ineffective antibiotics for patients with bloodstream infections

USTAR Center for Genetic Discovery to integrate genome data with patient care

UCLA creates new program that helps adoptive parents, children navigate through international adoption process

Medivir announces phase III ATTAIN study of simeprevir inhibitor in treatment of adult patients with HCV

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