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COVID-19 vaccine gaps linked to higher hospitalization and death rates in the UK

Between a third and a half of the populations of the four UK nations had not had the recommended number of COVID vaccinations and boosters by summer 2022, according to the first research study to look at COVID-19 vaccine coverage of the entire UK population.

16 Jan 2025

New scoring system developed to recognize and reward senior doctors and dentists

A team of researchers has developed a new scoring system for a nationwide scheme, overseen by the Advisory Committee on Clinical Impact Awards (ACCIA), to recognise and reward senior doctors and dentists in England and Wales.

16 Jan 2025

Scientists discover how viral infection triggers autoimmune disease

Scientists at the Garvan Institute of Medical Research have discovered how a viral infection causes autoimmune disease, disproving a long-standing theory and opening a promising new approach to developing treatments for autoimmune conditions.

16 Jan 2025

AstraZeneca's Pioneering Research in Heart Failure and ATTR-CM

Mina Makar highlights AstraZeneca's commitment to advancing heart failure research and innovative therapies, addressing critical needs in cardiovascular health.

16 Jan 2025

"Smoke-free generation" concept could save billions in health-care costs

Smoking stubbornly remains a leading cause of disease, disability and death in Canada, even as prevalence rates have fallen significantly over the last 50 years.

16 Jan 2025

New research uncovers mechanisms behind osteoarthritis risk in postmenopausal women

Osteoarthritis (OA) is a condition that disproportionally affects postmenopausal women, and the millions affected can attest to the pain, reduced mobility and diminished quality of life that comes from this disease.

16 Jan 2025

Study uncovers why lupus patients have weaker response to COVID-19 vaccines

A recent study by Emory University researchers provides new insights into why the mRNA vaccines developed to fight COVID-19 in 2021 are less effective in patients with autoimmune diseases.

16 Jan 2025

Drug in breast cancer trials shows potential for treating blood cancers

Two new studies led by researchers at Washington University School of Medicine in St. Louis have identified a possible way to block the progression of several forms of blood cancer using a drug already in clinical trials against breast cancer.

16 Jan 2025

Study unveils role of TLE6 in male sperm development

Infertility is a major global challenge associated with physiological and psychological impact. Genetic mutations that affect early embryonic development, oocyte (egg cell) maturation, and fertilization have recently been studied as causes of infertility.

16 Jan 2025

Owlstone Medical announces $27 million USD first close in series E financing round

Owlstone Medical (“Owlstone”), the global leader in Breath Biopsy® for applications in early disease detection and precision medicine, today announced a first closing of $27 million (circa £22 million) in its Series E financing round.

16 Jan 2025

New research identifies key subtype of bacterial vaginosis that increases chlamydia risk

Women who develop bacterial vaginosis (BV) often later acquire chlamydia, a common and potentially serious sexually transmitted bacterial infection.

16 Jan 2025

Childhood vaccination rates, a rare health bright spot in struggling states, are slipping

Jen Fisher can do only so much to keep her son safe from the types of infections that children can encounter at school. The rest, she said, is up to other students and parents in their hometown of Franklin, Tennessee.

16 Jan 2025

A new AI tool for unlocking the secrets of spatial multi-omics in cancer

A new artificial intelligence-powered tool called MISO (Multi-modal Spatial Omics) can detect cell-level characteristics of cancer by looking at data from extremely small pieces of tissue-some as small as 400 square micrometers, equivalent to the width of five human hairs.

16 Jan 2025

Mouse protein disrupts cancer-causing epigenetic changes in human colorectal cancer

A little-known mouse protein disrupts cancer-causing chemical changes to genes associated with human colorectal cancer cells and potentially could be used to treat solid tumors, according to a new study from researchers at the Johns Hopkins Kimmel Cancer Center and the Chinese Academy of Sciences.

16 Jan 2025

Leveraging CGP and ctDNA for improved cancer outcomes

Researchers from Iwate Medical University and Tohoku University have revealed that it is possible to predict cancer relapse and treatment response by measuring circulating tumor DNA (ctDNA), in tandem with data from comprehensive genomic profiling (CGP).

16 Jan 2025

Unveiling the genetic roots of bicuspid aortic valve

Large and rare duplications and deletions in a chromosome region known as 22q11.2 , which involves genes that regulate cardiac development, are linked to nonsyndromic bicuspid aortic valve disease, according to a new study led by UTHealth Houston researchers.

16 Jan 2025

T-DM1 reduces long-term risk of death in HER2-positive breast cancer patients

In patients with high-risk HER2-positive breast cancer, post-surgery, or adjuvant, treatment with trastuzumab emtansine (T-DM1) reduced the long-term risk of death or invasive disease by 46% and improved survival compared to trastuzumab alone, according to the final results of the phase 3 KATHERINE clinical trial led by researchers from the University of Pittsburgh and UPMC Hillman Cancer Center.

16 Jan 2025

Tiny vesicles offer powerful new approach for cancer treatment

A new twist on a decades-old anticancer strategy has shown powerful effects against multiple cancer types in a preclinical study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

16 Jan 2025

Xenon gas offers potential neuroprotective effects for Alzheimer's patients

Most treatments being pursued today to protect against Alzheimer's disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research from Mass General Brigham and Washington University School of Medicine in St. Louis points to a novel-and noble-approach: using Xenon gas.

16 Jan 2025

Air pollution before conception may increase child BMI

In a study of more than 5,000 mothers and their children, exposure to air pollution during the three months before pregnancy predicted higher child body mass index (BMI) and related obesity risk factors up to two years of age.

15 Jan 2025