Clinical Trial News and Research

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New clinical study aims to prevent onset of epilepsy in children with tuberous sclerosis

A clinical trial of a drug that researchers hope can prevent or delay the onset of epilepsy in children with tuberous sclerosis has begun at McGovern Medical School at The University of Texas Health Science Center at Houston.

8 May 2017

FDA approves new treatment for people with ALS

The U.S. Food and Drug Administration today approved Radicava (edaravone) to treat patients with amyotrophic lateral sclerosis, commonly referred to as Lou Gehrig's disease.

5 May 2017

FDA approves new AML drug after clinical testing at Dana-Farber

A targeted drug whose clinical testing was led by Richard Stone, MD, of Dana-Farber Cancer Institute, has become the first new treatment for newly diagnosed acute myeloid leukemia (AML) in more than 25 years.

5 May 2017

Advancing safety in healthcare products

True benefit from healthcare products requires an unrelenting focus on patient- and consumer-centered safety, a principle that is at the heart of J&J’s Credo and is embodied in the mission of the Office of the Chief Medical Officer (OCMO).

From Johnson & Johnson 5 May 2017

Study shows first removal of HIV-1 replication using CRISPR/Cas9, gene editing technology

A new study published in the journal Molecular Therapy reveals that HIV DNA in the genome of living animals can be removed to eliminate further infection. While a permanent cure for infection caused by HIV remains a challenge due to the ability of the virus to hide away in latent reservoirs. The study team comprising Wenhui Hu, Kamel Khalili, Laura H. Carnell, and Won-Bin Young carried out an experiment on three different animal models.

4 May 2017

Breakthrough therapy reduces symptoms of Graves' eye disease in clinical trials

The disease is characterized by inflammation and a buildup of tissue around the eyes that cause them to bulge painfully from their sockets.

4 May 2017

Steroids offer no additional relief to emergency patients suffering from hives

Despite standard use for the itching associated with urticaria (commonly known as hives), prednisone (a steroid) offered no additional relief to emergency patients suffering from hives than a placebo did, according to a randomized, placebo-controlled, double-blind, parallel-group study published online yesterday in Annals of Emergency Medicine.

4 May 2017

Study provides evidence for antidepressant effects of ketamine

Better known as an anesthetic or as an illicit hallucinogenic drug, ketamine has also long been noted for alleviating depression. But ketamine has not been tested in a large clinical trial, and all evidence of its antidepressant effects has come from anecdotes and small studies of fewer than 100 patients.

3 May 2017

Study suggests how existing and emerging immunotherapy treatments could be successful for sarcomas

Sarcomas- cancers of the connective tissues like muscles, joints, fat and bone - come in dozens of subtypes. Clinical trial results have been mixed when treating these diverse tumors with immunotherapy, a targeted therapeutic strategy that has success in other cancers.

3 May 2017

Adventist Health System, Bio-Optronics partner on CTMS deployment to foster clinical research excellence

Bio-Optronics and Adventist Health System (AHS) have announced the implementation and initial rollout of the Clinical Conductor Clinical Trial Management System (CTMS) at two of the faith-based health care system’s research institutes. This deployment, which included a CTMS-EMR integration with Cerner Millennium, will maximize process efficiency and enhance the organization’s overall research quality.

3 May 2017

Access to prostate cancer treatments in the UK

A major reason for the unmet need in prostate cancer in the UK is the length of time it takes to get new treatments through the reimbursement system with NICE (National Institute for Health and Care Excellence). This has a long-term impact on the UK, making the UK far behind the rest of Europe and even globally in terms of standard of care.

2 May 2017

Study finds shorter course of radiation therapy given after mastectomy to be safe and effective

A shorter course of radiation therapy given to breast cancer patients following mastectomy is safe and effective and cuts treatment time in half. That is according to data from a phase II clinical trial conducted by Rutgers Cancer Institute of New Jersey investigators and other colleagues who examined a hypofractionated regimen given over three weeks versus the traditional six week course of treatment.

2 May 2017

Combination therapy may be effective option for treating some women with ovarian cancer

Researchers have been trying to understand why up to 85 percent of women experience recurrence of high-grade serous ovarian cancer -- the most common subtype of ovarian cancer -- after standard treatment with the chemotherapy drug carboplatin.

2 May 2017

New study shows that gene editing technology can shut down HIV-1 replication in animals

A permanent cure for HIV infection remains elusive due to the virus's ability to hide away in latent reservoirs. But now, in new research published in print May 3 in the journal Molecular Therapy, scientists at the Lewis Katz School of Medicine at Temple University and the University of Pittsburgh show that they can excise HIV DNA from the genomes of living animals to eliminate further infection.

2 May 2017

Scientists aim to offer better treatment for acute heart failure using ultrasound evaluation

A new clinical study of the German Centre for Cardiovascular Research is examining whether an ultrasound evaluation of the inferior vena cava in acute decompensated heart failure with congestion can be implemented in hospitals' everyday routine and also be conducted in a sufficiently large number of patients.

28 Apr 2017

New study aims to test safety and efficacy of antiplatelet drug in preventing blood clots

A new clinical study is starting at the German Centre for Cardiovascular Research (DZHK) with an innovative and highly specific blood thinner.

28 Apr 2017

Study suggests ‘synergistic’ link between exercise and vitamin D for better heart health

Johns Hopkins researchers report that an analysis of survey responses and health records of more than 10,000 American adults for nearly 20 years suggests a "synergistic" link between exercise and good vitamin D levels in reducing the risk of heart attacks and strokes.

27 Apr 2017

Clinical Trial News and Research

New clinical study aims to prevent onset of epilepsy in children with tuberous sclerosis

FDA approves new treatment for people with ALS

FDA approves new AML drug after clinical testing at Dana-Farber

Advancing safety in healthcare products

Study shows first removal of HIV-1 replication using CRISPR/Cas9, gene editing technology

Breakthrough therapy reduces symptoms of Graves' eye disease in clinical trials

Steroids offer no additional relief to emergency patients suffering from hives

Study provides evidence for antidepressant effects of ketamine

Study suggests how existing and emerging immunotherapy treatments could be successful for sarcomas

Adventist Health System, Bio-Optronics partner on CTMS deployment to foster clinical research excellence

Access to prostate cancer treatments in the UK

Study finds shorter course of radiation therapy given after mastectomy to be safe and effective

Combination therapy may be effective option for treating some women with ovarian cancer

New study shows that gene editing technology can shut down HIV-1 replication in animals

Scientists aim to offer better treatment for acute heart failure using ultrasound evaluation

New study aims to test safety and efficacy of antiplatelet drug in preventing blood clots

Study suggests ‘synergistic’ link between exercise and vitamin D for better heart health

Clinical trial discovers drug combination that could help children with arthritis

Scientists announce ‘outstanding’ results of new blood cancer study

PolyU expert designs novel ’Smart Scar-Care’ pad to treat hypertrophic scars

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

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