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Controlling zinc transporter levels could be effective plan to combat pancreatic cancer, other diseases

When trace elements rise to toxic levels, bad things happen. Patients suffering from Alzheimer's and Parkinson's disease harbor significantly higher levels of zinc and iron in their brains than healthy patients.

6 Sep 2017

Molecular map shows novel way to stop dangerous bioweapon

During World War II, the Soviet Red Army was forced to move their biological warfare operations out of the path of advancing Nazi troops. Among the dangerous cargo were vials of Francisella tularensis, the organism that causes tularemia and one of the world's most infectious pathogens.

6 Sep 2017

Molecular analysis confirms zoonotic transmission of malaria in Atlantic Forest area in southern Brazil

Malaria was eliminated from southern and southeastern Brazil over 50 years ago, but a number of cases each year in areas of the Atlantic Forest prompted researchers to investigate the possibility of zoonotic transmission - where human beings become infected, via a mosquito bite, with a malaria parasite that usually infects monkeys.

6 Sep 2017

Largest ever genetic study paves way for potential osteoporosis treatment

Scientists are honing in on a potential treatment for osteoporosis, after performing the largest ever genetic study of the common age-related bone-thinning disease.

5 Sep 2017

Scientists show how receptors for drugs act inside cells

G protein-coupled receptors are the key target of a large number of drugs. Würzburg scientists have now been able to show more precisely how these receptors act in the cell interior.

5 Sep 2017

Researchers decode complex finger millet genome in high quality for first time

Finger millet has two important properties: The grain is rich in important minerals and resistant towards drought and heat.

5 Sep 2017

Researchers identify gene variants linked to both type 2 diabetes and CHD risk

Type 2 diabetes (T2D) has become a global epidemic affecting more than 380 million people worldwide; yet there are knowledge gaps in understanding the etiology of type-2 diabetes.

4 Sep 2017

Existing drug may one day protect premenopausal women from infertility after cancer treatments

An existing drug may one day protect premenopausal women from life-altering infertility that commonly follows cancer treatments, according to a new study.

1 Sep 2017

New discovery suggests choanos ‘eavesdrop’ on bacteria to regulate their life history

To the surprise of scientists, bacteria can act as an aphrodisiac for one-celled marine organisms notable for being the closest living relative of all animals.

1 Sep 2017

Scientists question CRISPR human embryo editing claims

A paper published in the journal Nature on the 2nd August described how a gene editing tool CRISPR could be used to correct a genetic mutation that leads to a heart condition. This team had performed the genetic editing on the gene sequences in dozens of viable human embryos to attempt to prevent a genetic heart condition called hypertrophic cardiomyopathy.

31 Aug 2017

Study identifies unexpected mosaic mutations as new risk factor for developing autism

Autism spectrum disorder affects approximately one out of every 68 children in the United States. Despite expansive study, the origin and risk factors of the complex condition are not fully understood.

31 Aug 2017

Study explores periodontal status of patients with Chédiak-Higashi syndrome

The International and American Associations for Dental Research have published an article titled "Periodontitis in Chédiak-Higashi Syndrome: An Altered Immunoinflammatory Response" in the JDR Clinical & Translational Research.

31 Aug 2017

St. Jude creates world’s largest collection of pediatric solid tumor samples

In an effort to improve outcomes for patients with some of the deadliest childhood cancers, St. Jude Children's Research Hospital scientists have created the world's largest collection of pediatric solid tumor samples, drug-sensitivity data and related information and have made the resource available at no charge to the global scientific community.

31 Aug 2017

Researchers decipher how some Listeria strains survive high food hygiene standards

Listeria monocytogenes is a foodborne pathogen that colonizes and reproduces on diverse food products including cheese or meat.

30 Aug 2017

Scientists aim is to better understand effects of DNA damage on aging process

The heredity substance DNA is the blueprint of our life. Like an instruction manual it contains all the information needed for cells and the body to function properly.

30 Aug 2017

Human ancestors responsible for transmitting ancient strains of herpesvirus, study finds

An international study of integrated HHV-6 has discovered that a small number of human ancestors, one from about 24,000 years ago, have been responsible for transmitting ancient strains of the virus to individuals today - affecting about a million people in the UK alone.

30 Aug 2017

Genetics of digestion stayed remarkably the same from fishes to humans, research shows

Scientists have discovered a network of genes and genetic regulatory elements in the lining of the intestines that has stayed remarkably the same from fishes to humans. Many of these genes are linked to human illnesses, such as inflammatory bowel diseases, diabetes and obesity.

30 Aug 2017

Scientists identify novel role for retrotransposons in shaping embryonic chromatin landscape

Retrotransposons are repetitive elements that form almost half of the mammalian genome. Even though they are so common, they have previously been considered to be fairly insignificant.

30 Aug 2017

Clinical benefit of LDL cholesterol lowering therapies could depend on reduction in apoB particles

The benefit of lowering low-density lipoprotein (LDL) cholesterol depends on how it is lowered, according to late-breaking results from a naturally randomised genetic trial presented today in a Hot Line - LBCT Session at ESC Congress1 and published in JAMA.

29 Aug 2017

Research findings potentially open door to new treatments for eye trauma and retinal disease

Cells within an injured mouse eye can be coaxed into regenerating neurons and those new neurons appear to integrate themselves into the eye's circuitry, new research shows. The findings potentially open the door to new treatments for eye trauma and retinal disease.

28 Aug 2017

Genome News and Research

Controlling zinc transporter levels could be effective plan to combat pancreatic cancer, other diseases

Molecular map shows novel way to stop dangerous bioweapon

Molecular analysis confirms zoonotic transmission of malaria in Atlantic Forest area in southern Brazil

Largest ever genetic study paves way for potential osteoporosis treatment

Scientists show how receptors for drugs act inside cells

Researchers decode complex finger millet genome in high quality for first time

Researchers identify gene variants linked to both type 2 diabetes and CHD risk

Existing drug may one day protect premenopausal women from infertility after cancer treatments

New discovery suggests choanos ‘eavesdrop’ on bacteria to regulate their life history

Scientists question CRISPR human embryo editing claims

Study identifies unexpected mosaic mutations as new risk factor for developing autism

Study explores periodontal status of patients with Chédiak-Higashi syndrome

St. Jude creates world’s largest collection of pediatric solid tumor samples

Researchers decipher how some Listeria strains survive high food hygiene standards

Scientists aim is to better understand effects of DNA damage on aging process

Human ancestors responsible for transmitting ancient strains of herpesvirus, study finds

Genetics of digestion stayed remarkably the same from fishes to humans, research shows

Scientists identify novel role for retrotransposons in shaping embryonic chromatin landscape

Clinical benefit of LDL cholesterol lowering therapies could depend on reduction in apoB particles

Research findings potentially open door to new treatments for eye trauma and retinal disease

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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