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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Researchers find new way for early prediction of leukemic relapse

Researchers at University of California San Diego School of Medicine and Moores Cancer Center have identified RNA-based biomarkers that distinguish between normal, aging hematopoietic stem cells and leukemia stem cells associated with secondary acute myeloid leukemia (sAML), a particularly problematic disease that typically afflicts older patients who have often already experienced a bout with cancer.

26 Aug 2016

Non-coding RNAs play key role in maintaining proper balance between fighting infection and inflammation

Special RNA molecules called long non-coding RNAs (lncRNAs) are key controllers for maintaining immune health when fighting infection or preventing inflammatory disorders, according to research led by Jorge Henao-Mejia, MD, PhD, an assistant professor of Pathology and Laboratory Medicine in the Perelman School of Medicine at the University of Pennsylvania.

25 Aug 2016

Scientists explore geochemical conditions that may have led to first relevant organophosphates

The phosphate ion is almost insoluble and is one of the most inactive of Earth's most abundant phosphate minerals. So how could phosphate have originally been incorporated into ribonucleotides, the building blocks of RNA, which are considered to be among the earliest constituents of life? American and Spanish scientists have now identified reasonable conditions to mobilize phosphate from insoluble apatite minerals for prebiotic organophosphate synthesis, including ribonucleotides.

24 Aug 2016

Researchers design DNA-based circuit that does math in a test tube

Often described as the blueprint of life, DNA contains the instructions for making every living thing from a human to a house fly.

24 Aug 2016

New chemical compound could potentially be used to treat Ebola virus infection

Scientists have found Ebola's Achilles' heel: a new kind of chemical compound can block the protein Ebola uses to break out of cells and infect new cells.

24 Aug 2016

Cloned Zika virus could be used for development of attenuated vaccine

Stopping the explosive spread of Zika virus - which can lead to birth defects in babies born to infected mothers - depends on genetic insights gleaned through new tools and models.

23 Aug 2016

Neuroscientists demonstrate revolutionary new way of mapping the brain at single-neuron resolution

Neuroscientists today publish in Neuron details of a revolutionary new way of mapping the brain at the resolution of individual neurons, which they have successfully demonstrated in the mouse brain.

19 Aug 2016

Researchers unravel mechanism by which hippocampal stem cells regulate their own fate

To date, it has been assumed that the differentiation of stem cells depends on the environment they are embedded in.

18 Aug 2016

Scientists find way to boost efficiency with which CRISPR-Cas9 cuts and disables genes

CRISPR-Cas9 is the go-to technique for knocking out genes in human cell lines to discover what the genes do, but the efficiency with which it disables genes can vary immensely.

18 Aug 2016

New book from Cold Spring Harbor examines major antibiotics and mechanisms of resistance

One of the greatest medical accomplishments of the past century was the introduction of antibiotics into the clinic.

18 Aug 2016

Mice study finds new approach to halt cycle of chronic inflammation in lupus

Molecules that scavenge debris from dying cells appear to halt the cycle of chronic inflammation in lupus, while also enhancing the body's ability to combat flu, according to Duke Health studies in mice.

17 Aug 2016

Researchers find potential way to reduce effects of TBI with neuron-targeting nanoparticle

A fall down the stairs, a car crash, a sports injury or an explosive blast can all cause traumatic brain injury (TBI).

17 Aug 2016

TSRI scientists tackle decades-old challenge by re-creating primordial RNA world

Scientists at The Scripps Research Institute (TSRI) have taken a big step toward the laboratory re-creation of the “RNA world,” which is generally believed to have preceded modern life forms based on DNA and proteins.

17 Aug 2016

Scientists develop novel method to widen usage of blood in biomarker discovery and analysis

Scientists at Karolinska Institutet in collaboration with Estonian Competence Centre on Health Technologies have developed a new gene expression analysis method to widen the usage of blood in biomarker discovery and analysis. Their paper is published in the journal Scientific Reports.

16 Aug 2016

Newfound role for PARP proteins could lead to therapeutic opportunities for cancer

Using technology they developed, UT Southwestern Medical Center researchers have identified a previously unknown role of a certain class of proteins: as regulators of gene activity and RNA processing.

16 Aug 2016

Researchers chart microbial ecology of the mouth at all stages of gum disease progression

Gingivitis, a common and mild form of gum disease can progress to periodontitis, a more serious infection that damages the soft tissue of the gums and sometimes even destroys the bone supporting the teeth.

12 Aug 2016

St. Jude scientists identify key innate immune sensor that attacks influenza virus

St. Jude Children's Research Hospital immunologists have identified the protein trigger in the body's quick-reaction innate immune system that specifically recognizes the influenza virus in infected cells and triggers their death.

12 Aug 2016

Former SpaceX engineers launch Synthego, CRISPRevolution to accelerate genome engineering research

Synthego, a leading provider of genome engineering solutions, officially launches today. Synthego’s flagship product line, CRISPRevolution, features synthetic guide RNA products designed to accelerate CRISPR/Cas9 and Cpf1 genome engineering research. CRISPRevolution is the first product line to offer economical access to fully synthetic RNA for high fidelity editing and increased precision in genome editing.

12 Aug 2016

Scientists discover key molecule that drives regeneration in planarian stem cells

Many living creatures possess exceptional abilities that set them apart from other species. Cheetahs can run up to 60 miles per hour; ants can lift 100 times their body weight; flatworms can regrow amputated body parts.

12 Aug 2016

Scientists find new functions of ANG protein that plays key role in regulation of blood cell formation

Tufts Medical Center and Tufts University scientists have found exciting, new functions of the protein angiogenin that play a significant role in the regulation of blood cell formation, important in bone marrow transplantation and recovery from radiation-induced bone marrow failure.

11 Aug 2016

RNA News and Research

Further Reading

Researchers find new way for early prediction of leukemic relapse

Non-coding RNAs play key role in maintaining proper balance between fighting infection and inflammation

Scientists explore geochemical conditions that may have led to first relevant organophosphates

Researchers design DNA-based circuit that does math in a test tube

New chemical compound could potentially be used to treat Ebola virus infection

Cloned Zika virus could be used for development of attenuated vaccine

Neuroscientists demonstrate revolutionary new way of mapping the brain at single-neuron resolution

Researchers unravel mechanism by which hippocampal stem cells regulate their own fate

Scientists find way to boost efficiency with which CRISPR-Cas9 cuts and disables genes

New book from Cold Spring Harbor examines major antibiotics and mechanisms of resistance

Mice study finds new approach to halt cycle of chronic inflammation in lupus

Researchers find potential way to reduce effects of TBI with neuron-targeting nanoparticle

TSRI scientists tackle decades-old challenge by re-creating primordial RNA world

Scientists develop novel method to widen usage of blood in biomarker discovery and analysis

Newfound role for PARP proteins could lead to therapeutic opportunities for cancer

Researchers chart microbial ecology of the mouth at all stages of gum disease progression

St. Jude scientists identify key innate immune sensor that attacks influenza virus

Former SpaceX engineers launch Synthego, CRISPRevolution to accelerate genome engineering research

Scientists discover key molecule that drives regeneration in planarian stem cells

Scientists find new functions of ANG protein that plays key role in regulation of blood cell formation

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