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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Study identifies inhibitor that protects cells from toxic DUX4 effects

About one in 8,000 people have facioscapulohumeral muscular dystrophy, according to a 2014 study, which is relatively common in the world of genetic diseases.

11 Sep 2019

New liquid biopsy test may be more predictive of patient's immunotherapy response

A new liquid biopsy test could detect microsatellite instability (MSI) and tumor mutational burden (TMB), indicating that it could help determine which patients are likely to respond to immune checkpoint inhibitors.

11 Sep 2019

Gene coding error likely responsible for rare form of inherited 'short telomere' disease

By combing through the entire genetic sequences of a person with a lung scarring disease and 13 of the person’s relatives, Johns Hopkins Medicine researchers say they have found a coding error in a single gene that is likely responsible for a rare form of the disease and the abnormally short protective DNA caps on chromosomes long associated with it.

From Johns Hopkins Medicine 11 Sep 2019

Oxford Genetics unveils OXGENE brand

Oxford Genetics Ltd announces the launch of its brand OXGENE™. The new brand articulates the company’s powerful ability to combine highly innovative science with an engineering approach to custom solutions for biotechnology.

From OXGENE 11 Sep 2019

Genetic engineering could open possibilities for patients with Parkinson’s disease

People with Parkinson’s disease experience loss of dopamine-producing brain cells, leading to tremors, rigidity, bradykinesia, and postural instability, the primary symptoms of the disease.

11 Sep 2019

Novel technology makes biopsies less invasive and more informative

A team of researchers from the National University of Singapore has developed a novel technology that could sensitively and accurately detect and classify cancer cells, as well as determine the disease aggressiveness from the least invasive biopsies.

10 Sep 2019

Long-term antibiotic use in preemies promotes drug-resistant gut bacteria

Very preterm infants are often sick and require antibiotic treatment to save their lives. However, when this form of therapy lasts for 20 months or more, it may affect the gut microbiome over the long-term in addition to its acute effects.

10 Sep 2019

Gut microbiome and IBD – the connection maybe in diet says study

A new study has shown conclusive evidence that inflammatory bowel disease or IBD is intimately associated with the gut microbial environment which can be altered with prescription diet. The microbiome within the human gut is a collection of healthy and helpful bacteria that help in several functions of the body including development and maintenance of immunity.

10 Sep 2019

Nanocapsules packed with gene-editing tools could be promising platform for many gene therapies

New tools for editing genetic code offer hope for new treatments for inherited diseases, some cancers, and even stubborn viral infections. But the typical method for delivering gene therapies to specific tissues in the body can be complicated and may cause troubling side effects.

10 Sep 2019

Liquid biopsies provide complete picture of genetic alterations linked to cancer drug resistance

Many patients see their tumors shrink in response to a drug, only to have them come back with a vengeance as they evolve to fend off the treatment. Oncologists want to be able to quickly detect cancer drug resistance as it emerges in their patients and identify another drug the tumors will still respond to.

10 Sep 2019

Mutations linked with sensitivity or resistance to immunotherapy in mNSCLC

The relationship between gene alterations and response to anti-PD-L1 with and without anti-CTLA-4 are not well characterized.

10 Sep 2019

Salk researchers develop method to reveal epigenetic features of brain cells

The brain's prefrontal cortex, which gives us our ability to solve problems and plan ahead, contains billions of cells. But understanding the large diversity of cell types in this critical region, each with unique genetic and molecular properties, has been challenging.

10 Sep 2019

Lung-MAP study: Majority of cancer patients don't understand genomic test results

A majority of cancer patients don't understand key aspects of the genomic test results they receive as participants in biomarker-driven clinical trials, according to a first-of-its-kind pilot study conducted under the Lung Cancer Master Protocol.

10 Sep 2019

Researchers develop new cocktail of drugs that shrink pancreatic tumors

Cancer is relentless and resilient. When a drug blocks a cancer cell's main survival pathway, the cell avoids the obstacle by taking different pathways or detours to save itself. This tactic is called "developing resistance," and it's one of the key challenges researchers face when seeking effective therapeutics to combat pancreatic ductal adenocarcinoma (PDA).

9 Sep 2019

Scientists reveal how typhoid toxin works to accelerate aging of cells

Scientists have revealed how the typhoid toxin works to hijack DNA repair machines and accelerate the aging of cells, a breakthrough that could pave the way for new strategies to combat the killer disease.

6 Sep 2019

UA receives $37.5 million NIH grant to research potential regenerative therapy for Alzheimer's

The University of Arizona Center for Innovation in Brain Science has received a $37.5 million grant from the National Institutes of Health to research a potential regenerative therapy for Alzheimer's disease.

6 Sep 2019

Lefthandedness genes change the way the brain develops

A new study has discovered four genes related to left-handedness, and the associated differences in the way the brain is organized. About a tenth of people are left-handed, making this a not uncommon trait. However, the new findings point to greater verbal fluency with this alternate version of the brain, compared to right-handedness.

6 Sep 2019

Newly discovered resistance-spreading mechanism is independent of the use of antibiotics

Bacteria are becoming increasingly resistant to common antibiotics. Often, resistance is mediated by resistance genes, which can simply jump from one bacterial population to the next.

5 Sep 2019

How tuberculosis progresses: genetic factors play a major role

There are almost 1.8 billion people with tuberculosis bacilli in their body, but only about 5% to 15% develop overt infection, usually within 18 months of initial exposure. The reason behind this selective progression has been sought for decades by scientists from a variety of fields.

5 Sep 2019

Researchers discover a molecule that regulates tumor development in different types of cancers

Researchers from the Josep Carreras Leukemia Research Institute, discover that a non-coding region of the genome originates a key molecule for the proliferation of tumors in breast cancer and some types of sarcoma.

5 Sep 2019

DNA News and Research

Further Reading

Study identifies inhibitor that protects cells from toxic DUX4 effects

New liquid biopsy test may be more predictive of patient's immunotherapy response

Gene coding error likely responsible for rare form of inherited 'short telomere' disease

Oxford Genetics unveils OXGENE brand

Genetic engineering could open possibilities for patients with Parkinson’s disease

Novel technology makes biopsies less invasive and more informative

Long-term antibiotic use in preemies promotes drug-resistant gut bacteria

Gut microbiome and IBD – the connection maybe in diet says study

Nanocapsules packed with gene-editing tools could be promising platform for many gene therapies

Liquid biopsies provide complete picture of genetic alterations linked to cancer drug resistance

Mutations linked with sensitivity or resistance to immunotherapy in mNSCLC

Salk researchers develop method to reveal epigenetic features of brain cells

Lung-MAP study: Majority of cancer patients don't understand genomic test results

Researchers develop new cocktail of drugs that shrink pancreatic tumors

Scientists reveal how typhoid toxin works to accelerate aging of cells

UA receives $37.5 million NIH grant to research potential regenerative therapy for Alzheimer's

Lefthandedness genes change the way the brain develops

Newly discovered resistance-spreading mechanism is independent of the use of antibiotics

How tuberculosis progresses: genetic factors play a major role

Researchers discover a molecule that regulates tumor development in different types of cancers

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