Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

New hope for people suffering from depression

There is new hope for people suffering from depression. Researchers have identified a compound, hydroxynorketamine (HNK), that may treat symptoms of depression just as effectively and rapidly as ketamine, without the unwanted side effects associated with the psychoactive drug, according to a study in the July issue of Anesthesiology, the official medical journal of the American Society of Anesthesiologists- (ASA-).

17 Jun 2014

Researchers develop rapid-acting antidepressants for treatment-resistant depression

UT Southwestern Medical Center researchers have generated fresh insights that could aid in the development of rapid-acting antidepressants for treatment-resistant depression.

13 Jun 2014

New prescription weight-loss medication combines antidepressant with addiction medication

A new prescription weight-loss medication that combines a popular antidepressant with a medication for addiction will be reviewed by the Federal Drug Administration (FDA) for potential approval.

11 Jun 2014

Alkermes initiates FORWARD-3 and FORWARD-4 efficacy studies in pivotal clinical program for ALKS 5461

Alkermes plc today announced the initiation of FORWARD-3 and FORWARD-4, two of the three planned phase 3 core efficacy studies in the pivotal clinical program for ALKS 5461, a once-daily, oral investigational medicine with a novel mechanism of action for the adjunctive treatment of major depressive disorder (MDD).

10 Jun 2014

Tiny molecule may provide marker for depression

Levels of a small molecule found only in humans and in other primates are lower in the brains of depressed individuals, according to researchers at McGill University and the Douglas Institute.

9 Jun 2014

Common antidepressant use during pregnancy may contribute to higher risk of ASD in children

A new study from researchers at Drexel University adds evidence that using common antidepressant medications during pregnancy may contribute to a higher risk of autism spectrum disorders (ASD) in children, although this risk is still very small.

4 Jun 2014

Allowing PTSD patients to choose their own treatment is less expensive, shows study

A cost-analysis of post-traumatic stress disorder treatments shows that letting patients choose their course of treatment - either psychotherapy or medication - is less expensive than assigning a treatment and provides a higher quality of life for patients.

29 May 2014

Case Western Reserve physician calls on FDA to address hidden risk of dangerous drugs side effects

The agency charged to protect patients from dangerous drug side effects needs to be far more vigilant when it comes to medications that affect blood pressure.

28 May 2014

Anti-depressants could slow onset of Alzheimer's disease

A University of Pennsylvania researcher has discovered that the common selective serotonin reuptake inhibitor (SSRI) citalopram arrested the growth of amyloid beta, a peptide in the brain that clusters in plaques that are thought to trigger the development of Alzheimer's disease (AD).

15 May 2014

Antidepressant stops growth of plaques in mouse model of Alzheimer's disease

A commonly prescribed antidepressant can reduce production of the main ingredient in Alzheimer's brain plaques, according to new research at Washington University School of Medicine in St. Louis and the University of Pennsylvania.

15 May 2014

Naurex's two lead antidepressant programs achieve major milestones

Naurex Inc., a privately held biopharmaceutical company leveraging its unique platform to develop novel drugs for diseases of the central nervous system (CNS), today announced that its two lead antidepressant programs achieved major milestones.

6 May 2014

Eye movement disorder increases as we age, study finds

Abnormal binocular vision, which involves the way eyes work together as a team, increases dramatically as we age, according to research from the University of Waterloo. The study also found a correlation between this condition, general health and antidepressant use.

2 May 2014

Researchers demonstrate possibility of using blood test to detect depression

Researchers at the MedUni Vienna have demonstrated the possibility of using a blood test to detect depression. While blood tests for mental illnesses have until recently been regarded as impossible, a recent study clearly indicates that, in principle, depression can in fact be diagnosed in this way and this could become reality in the not too distant future.

30 Apr 2014

Study: Depression affects more than one out of three critical care survivors

Depression affects more than one out of three survivors of critical illness, according to a Vanderbilt study released in The Lancet Respiratory Medicine, and the majority of patients experience their symptoms physically rather than mentally.

26 Apr 2014

Study points to new therapeutic strategy for treating depression

A new study points to a conceptually novel therapeutic strategy for treating depression. Instead of dampening neuron firing found with stress-induced depression, researchers demonstrated for the first time that further activating these neurons opens a new avenue to mimic and promote natural resilience.

21 Apr 2014

New antidepressants open promising perspective for management of treatment-resistant depression

Notwithstanding numerous advances in the pharmacological treatment of depression, approximately 70% of patients do not remit after first-line antidepressant treatment.

15 Apr 2014

Women on antidepressant medication are more successful at breastfeeding

University of Adelaide researchers have found that women on antidepressant medication are more successful at breastfeeding their babies if they keep taking the medication, compared with women who quit antidepressants because of concerns about their babies' health.

11 Apr 2014

Viewpoints: A 'misguided' debate; trying to figure out who's uninsured; the safety net for the middle class

Supporters of Obamacare are celebrating that the law is not an unmitigated disaster, just a mitigated one. As enrollment closed (for most) on March 31, the system passed 7 million exchange sign-ups.

9 Apr 2014

Intranasal ketamine spray confers rapid antidepressant effect in patients with depressive disorder

A research team from the Icahn School of Medicine at Mount Sinai published the first controlled evidence showing that an intranasal ketamine spray conferred an unusually rapid antidepressant effect -within 24 hours-and was well tolerated in patients with treatment-resistant major depressive disorder.

9 Apr 2014

Depression linked to poor self-management in patients with diabetes

Adult patients with diabetes who trust their medical provider and feel included in treatment decisions are significantly more likely to take and maintain a newly prescribed antidepressant medication, according to a new study in the Journal of General Internal Medicine.

9 Apr 2014

Antidepressant News and Research

Further Reading

New hope for people suffering from depression

Researchers develop rapid-acting antidepressants for treatment-resistant depression

New prescription weight-loss medication combines antidepressant with addiction medication

Alkermes initiates FORWARD-3 and FORWARD-4 efficacy studies in pivotal clinical program for ALKS 5461

Tiny molecule may provide marker for depression

Common antidepressant use during pregnancy may contribute to higher risk of ASD in children

Allowing PTSD patients to choose their own treatment is less expensive, shows study

Case Western Reserve physician calls on FDA to address hidden risk of dangerous drugs side effects

Anti-depressants could slow onset of Alzheimer's disease

Antidepressant stops growth of plaques in mouse model of Alzheimer's disease

Naurex's two lead antidepressant programs achieve major milestones

Eye movement disorder increases as we age, study finds

Researchers demonstrate possibility of using blood test to detect depression

Study: Depression affects more than one out of three critical care survivors

Study points to new therapeutic strategy for treating depression

New antidepressants open promising perspective for management of treatment-resistant depression

Women on antidepressant medication are more successful at breastfeeding

Viewpoints: A 'misguided' debate; trying to figure out who's uninsured; the safety net for the middle class

Intranasal ketamine spray confers rapid antidepressant effect in patients with depressive disorder

Depression linked to poor self-management in patients with diabetes

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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