Blood Clot News and Research

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A Blood Clot is a mass of blood that forms when blood platelets, proteins, and cells stick together. When a blood clot is attached to the wall of a blood vessel, it is called a thrombus. When it moves through the bloodstream and blocks the flow of blood in another part of the body, it is called an embolus.

Research findings open up possibility for developing potent anti-clotting drugs

Researchers at the University of Illinois at Chicago have discovered a molecular switch that causes small, beneficial clots that stop bleeding to enlarge further during wound healing. By blocking this switch in lab mice, the researchers prevented small clots from growing -- a process that can pose a danger in humans -- while preserving their ability to staunch bleeding

29 Oct 2013

Hands-free ultrasound device with clot-busting drug safe for ischemic stroke patients

A study led by researchers at The University of Texas Health Science Center at Houston (UTHealth) showed that a hands-free ultrasound device combined with a clot-busting drug was safe for ischemic stroke patients.

25 Oct 2013

DSM, Sanquin Make Factor IX-Recovering Mab Manufacturing Deal

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24 Oct 2013

UTHealth researchers investigate clot-buster for children with acute ischemic stroke

Researchers at The University of Texas Health Science Center at Houston are part of a multi-center, international study investigating the safety and best dosage of a clot-buster for children with acute ischemic stroke.

24 Oct 2013

Detecting dangerous blood clots in the form of simple urine test

Detecting dangerous blood clots, which can cause life-threatening conditions such as strokes and heart attacks, leading causes of death for men and women in the U.S., has been a coveted and elusive goal.

17 Oct 2013

Simple urine test uses nanotechnology to detect dangerous blood clotting

Life-threatening blood clots can form in anyone who sits on a plane for a long time, is confined to bed while recovering from surgery, or takes certain medications.

17 Oct 2013

Research shows inhibition of Rcan1 protein may reduce atherosclerosis in mice

Researchers of the Spanish research council (Consejo Superior de Investigaciones Cient-ficas, CSIC) and the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have discovered that inhibiting the protein Rcan1 in mice reduces the burden of atherosclerosis, one of the commonest cardiovascular diseases.

16 Oct 2013

Research roundup: Medicare Part D in 2014; barriers to mental health care; scattered patterns of ACOs

Medicare Part D continues to be a marketplace with an array of competing plans offered at a wide range of premiums and benefit designs. In 2014, Medicare beneficiaries will have a choice of 35 stand-alone PDPs, on average, up by four from 2013. ... Beneficiaries receiving Low-Income Subsidies will have access to a modestly higher number of plans for no monthly premium in 2014 compared to 2013 ... Notable trends for 2014 include a growing share of PDPs using preferred pharmacy networks and adopting more formulary cost-sharing tiers.

12 Oct 2013

Scientists introduce new approach to the production of synthetic heparin mimetics

One of the risks of any large operation is the occurrence of blood clots. To prevent this, patients are routinely given the anticoagulant heparin or related drugs. American scientists have now introduced a new approach to the production of synthetic heparin mimetics with better activity profiles.

11 Oct 2013

Researchers find no serious adverse effects of HPV vaccine in girls

Researchers at Karolinska Institutet in Sweden and their Danish colleagues have monitored HPV-vaccinated girls via patient data registries in order to examine the incidence of a wide range of diseases and thus determine if there are any serious adverse effects of the vaccine. Their results show no significant increase of the examined diseases in the vaccinated girls relative to their unvaccinated peers.

10 Oct 2013

Understanding the biological players in clot formation could lead to new thrombotic therapies

Ulhas Naik, professor of biological sciences and director of the Delaware Cardiovascular Research Center, pores over laboratory data on his computer, even during breakfast most mornings. He is on a quest to tease out the roles that various blood components play in the formation of clots.

9 Oct 2013

Viewpoints: Whether Americans will like health law is open question; GOP has 'nothing to show' for shutdown; Sebelius says demand derailed marketplace's debut

How absolutely bonkers. And yet how unsurprising. We're awash these days in metaphors as overworked as our political debate is overwrought, and it's impossible not to wonder how much one contributes to the other. When nuance and perspective exit the language, do they exit the conversation as well? When you speak in ludicrous extremes, do you think that way, too? Obamacare has proved to be not just ideologically divisive but linguistically fertile. There's seemingly no event or passage in American history to which it can't be compared (Frank Bruni, 10/7).

9 Oct 2013

Cost issues: Expensive patients; payoff from delaying aging; approving new treatments

Cost and quality issues in the news include research about the costliest U.S. patients, the potential that delaying aging instead of treating disease could have on extending life, and examining how the U.S. compares to other countries on approving new medical treatments.

9 Oct 2013

Bayer HealthCare receives FDA approval for Adempas tablets

Bayer HealthCare announced today that the United States Food and Drug Administration has approved Adempas (riociguat) tablets for: (i) the treatment of adults with persistent/recurrent chronic thromboembolic pulmonary hypertension (WHO Group 4) after surgical treatment or inoperable CTEPH to improve exercise capacity and WHO functional class; and (ii) the treatment of adults with pulmonary arterial hypertension (WHO Group 1) to improve exercise capacity, improve WHO functional class and delay clinical worsening.

9 Oct 2013

First Edition: October 8, 2013

Today's headlines include the latest on how the health law's online insurance marketplaces are operating and what caused the initial systemic problems.

8 Oct 2013

Statin medications pose no threat to short-term memory and may protect against dementia

A review of dozens of studies on the use of statin medications to prevent heart attacks shows that the commonly prescribed drugs pose no threat to short-term memory, and that they may even protect against dementia when taken for more than one year.

2 Oct 2013

Researchers compare cardiovascular safety of two commonly used oral estrogen medications

The oral hormone therapy conjugated equine estrogens, which is used by women to relieve menopause symptoms, appears to be associated with increased risk for venous thrombosis (VT, blood clots) and possibly myocardial infarction (heart attack), but not ischemic stroke risk, when compared with the hormone therapy oral estradiol, according to a study published by JAMA Internal Medicine, a JAMA Network publication.

1 Oct 2013

FDA expands Hizentra administration options for people with primary immunodeficiency

CSL Behring announced today that the U.S. Food and Drug Administration has expanded the administration options for Hizentra, Immune Globulin Subcutaneous (Human), 20% Liquid, to include dosing once every two weeks (biweekly) for people diagnosed with primary immunodeficiency.

28 Sep 2013

Majority of qualified patients fail to receive lifesaving treatment for sudden cardiac arrest: Study

A new study of patients who died of sudden cardiac arrest, a usually fatal condition that causes the heart to stop beating, shows the majority who qualified to receive potentially lifesaving treatment did not receive it.

25 Sep 2013

Smoking may increase risk of complications, death after colorectal procedures

Infection, pneumonia, blood clots and kidney failure are all possible complications after any major surgery. A new study shows that smoking boosts the risk of such complications following some of the most common colorectal procedures, including surgery for colon cancer, diverticulitis or inflammatory bowel disease.

25 Sep 2013

Blood Clot News and Research

Further Reading

Research findings open up possibility for developing potent anti-clotting drugs

Hands-free ultrasound device with clot-busting drug safe for ischemic stroke patients

DSM, Sanquin Make Factor IX-Recovering Mab Manufacturing Deal

UTHealth researchers investigate clot-buster for children with acute ischemic stroke

Detecting dangerous blood clots in the form of simple urine test

Simple urine test uses nanotechnology to detect dangerous blood clotting

Research shows inhibition of Rcan1 protein may reduce atherosclerosis in mice

Research roundup: Medicare Part D in 2014; barriers to mental health care; scattered patterns of ACOs

Scientists introduce new approach to the production of synthetic heparin mimetics

Researchers find no serious adverse effects of HPV vaccine in girls

Understanding the biological players in clot formation could lead to new thrombotic therapies

Viewpoints: Whether Americans will like health law is open question; GOP has 'nothing to show' for shutdown; Sebelius says demand derailed marketplace's debut

Cost issues: Expensive patients; payoff from delaying aging; approving new treatments

Bayer HealthCare receives FDA approval for Adempas tablets

First Edition: October 8, 2013

Statin medications pose no threat to short-term memory and may protect against dementia

Researchers compare cardiovascular safety of two commonly used oral estrogen medications

FDA expands Hizentra administration options for people with primary immunodeficiency

Majority of qualified patients fail to receive lifesaving treatment for sudden cardiac arrest: Study

Smoking may increase risk of complications, death after colorectal procedures

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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