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Muscle dystrophy treatment in dogs with Crispr gene editing

Researchers in the United States have shown that genetically caused muscular dystrophy in dogs could be corrected using genetic editing tools. Muscular dystrophy is one of the most common fatal genetic conditions seen in children and is also seen in dogs

31 Aug 2018

Researchers develop faster method to grow brain cells from stem cells

Researchers at Lund University in Sweden have developed a faster method to generate functional brain cells, called astrocytes, from embryonic stem cells. Astrocytes play a significant role in neurodegenerative diseases.

22 Aug 2018

Study reveals why individuals carrying identical gene mutations have varying disease severity

Researchers at the New York Genome Center and Columbia University have uncovered a molecular mechanism behind one of biology's long-standing mysteries: why individuals carrying identical gene mutations for a disease end up having varying severity or symptoms of the disease.

20 Aug 2018

Researchers map sugar structures in 'library of sugars'

Most of us tend to think of sugar as a temptation that threatens our health. The reality is, however, that sugar is an essential component of the human body; it covers the surface of our cells and proteins, and tunes the behaviour and function of our tissues in both health and disease.

14 Aug 2018

Using CRISPR-Cas9 genome editing to correct mutation responsible for sickle cell disease

Genome editing using the CRISPR-Cas9 system has tremendous promise for therapeutic correction of genetic errors in human cells. Prior to adoption as a medical therapeutic, safety concerns relating to off-target effects must be minimized to mitigate risks that may arise from the unintended action of this system at sites similar, but not identical, to the desired gene target site.

From Integrated DNA Technologies 10 Aug 2018

Researchers discover genetic mutation underlying debilitating childhood brain disorder

Ashleigh Schaffer, PhD, assistant professor of genetics at Case Western Reserve University School of Medicine, and a team of global genetics experts have discovered a genetic mutation and the faulty development process it triggers, causing a debilitating brain-based disorder in children.

9 Aug 2018

Researchers use DNA editing tool to reveal mechanisms behind autoimmune diseases

A group of researchers at the University of São Paulo in Brazil used a DNA editing tool called CRISPR/Cas9 to manipulate on of the genes associated to the autoaggressive T lymphocytes responsible for inducing autoimmune diseases such as autoimmune polyglandular syndrome type 1 and type 1 diabetes.

2 Aug 2018

Innovative 'EvolvR' system lets scientists shuffle genes until they get right variation

Scientists at the Innovative Genomics Institute have concocted a transformative new way to harness the power of evolution.

2 Aug 2018

Scientists find people's assumptions about DNA repair after CRISPR editing to be wrong

Despite high hopes and high investment in CRISPR-Cas9 gene editing, scientists still have a lot to learn about how it works in humans.

31 Jul 2018

Researchers discover various mechanisms of resistance to cancer therapy

An international research team under the co-direction of the University of Bern and the Netherlands Cancer Institute has discovered various mechanisms of resistance to cancer therapy. The findings help researchers to understand the self-repair of cancer cells after a therapy and thus help to fight resistant tumours more efficiently.

30 Jul 2018

Most Americans skeptical about gene editing

A new survey from Pew Research Center has found that nearly half of the surveyed Americans believe that in the coming 50 years, nearly all genetic birth defects could be eliminated due to advances in gene editing.

26 Jul 2018

MODEL-AD Center releases eight new mouse models for Alzheimer's research

The MODEL-AD Center, an ambitious project to develop and distribute precise mouse models of late-onset Alzheimer's disease (AD), has released eight new models carrying genetic mutations found in patients.

23 Jul 2018

New breeding technologies could enhance shape, size, color, and health benefits of produce

Forget vegetables with dull colors and fuzzy skin or fruits that lack of flavor--the produce aisle of the future could offer plant products that are designed for creative cooks and fussy eaters.

20 Jul 2018

Researchers uncover cause for progression of prostate cancer to incurable stage

Researchers at the University of Oulu in Finland have discovered novel genes and mechanisms that can explain how a genomic variant in a single nucleotide polymorphism rs11672691 influences prostate cancer aggressiveness.

20 Jul 2018

Study uncovers new protein complex that shields broken DNA ends

Scientists have made a major discovery about how cells repair broken strands of DNA that could have huge implications for the treatment of cancer.

19 Jul 2018

CRISPR/Cas9 gene editing can cause greater genetic damage than previously thought

Scientists at the Wellcome Sanger Institute have discovered that CRISPR/Cas9 gene editing can cause greater genetic damage in cells than was previously thought. These results create safety implications for gene therapies using CRISPR/Cas9 in the future as the unexpected damage could lead to dangerous changes in some cells.

16 Jul 2018

Cas9 News and Research

Muscle dystrophy treatment in dogs with Crispr gene editing

Researchers develop faster method to grow brain cells from stem cells

Study reveals why individuals carrying identical gene mutations have varying disease severity

Researchers map sugar structures in 'library of sugars'

Using CRISPR-Cas9 genome editing to correct mutation responsible for sickle cell disease

Researchers discover genetic mutation underlying debilitating childhood brain disorder

Researchers use DNA editing tool to reveal mechanisms behind autoimmune diseases

Innovative 'EvolvR' system lets scientists shuffle genes until they get right variation

Scientists find people's assumptions about DNA repair after CRISPR editing to be wrong

Researchers discover various mechanisms of resistance to cancer therapy

Most Americans skeptical about gene editing

MODEL-AD Center releases eight new mouse models for Alzheimer's research

New breeding technologies could enhance shape, size, color, and health benefits of produce

Researchers uncover cause for progression of prostate cancer to incurable stage

Study uncovers new protein complex that shields broken DNA ends

CRISPR/Cas9 gene editing can cause greater genetic damage than previously thought

Growing pains in CRISPR gene editing

Researchers discover why CRISPR gene editing sometimes fails

Researchers reveal why CRISPR gene editing sometimes fails to work

Fluorescent fish could help find origins of neuroblastoma

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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