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New dual drugs eliminate tumors when combined with immunotherapy

Researchers at Johns Hopkins University and the University of Maryland School of Pharmacy have developed a set of novel, first-in-class drugs that inhibit hypoxia-inducible factors 1 and 2, a pair of transcription factors considered to be "master regulators" of cancer progression.

2 Apr 2026

NIH funds AI project to advance Alzheimer’s research and treatment

The National Institutes of Health has renewed support for Artificial Intelligence for Alzheimer's Disease, or AI4AD. The new $12.6 million award to advance the project's next phase, AI4AD2, brings its total investment in AI4AD to $30.7 million.

1 Apr 2026

New brain circuit discovery offers hope for chronic pain treatment

A new map of a brain circuit specific to chronic pain suggests a promising route to treatment for the roughly 60 million Americans living with persistent pain, according to a study published in Nature.

1 Apr 2026

Small molecule may block protein buildup in neurodegenerative diseases

A team of researchers from NYU Abu Dhabi and the University of Denver have identified a promising small molecule that could help slow or halt the progression of serious brain diseases such as Parkinson's disease, offering new hope for treatments that go beyond managing symptoms.

1 Apr 2026

Popular vitamin B3 supplements could weaken cancer therapy effectiveness

Millions of Americans take daily supplements-nicotinamide mononucleotide (NMN), nicotinamide riboside (NR) and nicotinamide (NAM)-to boost energy, slow aging and protect the heart and brain.

1 Apr 2026

Highly potent opioid shows potential as therapy for pain and opioid use disorder

Researchers at the National Institutes of Health (NIH) have identified a novel, highly potent opioid that shows potential as a therapy for both pain and opioid use disorder.

1 Apr 2026

Molecular switch in neurons found to limit the regrowth of damaged axonal fibers

Researchers from the Icahn School of Medicine at Mount Sinai have discovered a molecular switch in neurons that limits the regrowth of damaged axonal fibers.

1 Apr 2026

"Smart" system distinguishes and neutralizes cancer cells with unprecedented precision

A team from UNIGE has designed a molecular system that distinguishes and neutralizes cancer cells with unprecedented precision, paving the way for autonomous, self-regulating drugs.

1 Apr 2026

Trump’s one big beautiful bill act darkens outlook for government-backed clinics

Bluestem Health, a clinic that serves low-income and uninsured patients in Lincoln, Nebraska, has lost money for the last two years.

1 Apr 2026

Large study links more siblings to better bereavement coping

Having more brothers and sisters may make it easier to cope with the death of a parent, in midlife, particularly when it's the mother who dies, suggests research published online in the Journal of Epidemiology & Community Health.

1 Apr 2026

Purdue University accelerates rare disease drug discovery with the WELLJET dispenser stacker

Scientists at Purdue University are using the WELLJET dispenser stacker from INTEGRA Biosciences to increase the speed, consistency and scale of drug screening for rare and neglected parasitic diseases.

1 Apr 2026

Study reveals how extracellular matrix stiffness regulates breast cancer metastasis

A study by researchers at the University of California San Diego could make it easier to treat breast cancer by uncovering a new way the body helps prevent its spread.

31 Mar 2026

Novel compound clears harmful protein, protects neurons in frontotemporal dementia models

New research from Washington University School of Medicine in St. Louis adds to growing evidence that helping brain cells break down and eliminate their own cellular waste is a promising treatment strategy for a variety of neurodegenerative diseases.

31 Mar 2026

Digoxin found safe to use in young patients with rheumatic heart disease

Patients with rheumatic heart disease who took the heart failure drug digoxin were 18% less likely to die or experience new-onset or worsening heart failure during a two-year follow-up compared with those who received a placebo, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.26).

30 Mar 2026

CFHR1 could be a new diagnostic marker for IgA nephropathy

Immunoglobulin A (IgA) nephropathy is an autoimmune disease characterized by the deposition of circulating IgA-containing immune complexes (IgA-ICs) in the glomerular mesangium, leading to mesangial cell proliferation, enhanced extracellular matrix production, and variable infiltration of inflammatory cells.

30 Mar 2026

NOX-1 identified as key molecular target to prolong ketamine's antidepressant effects

Treatment-resistant depression affects a large proportion of people with major depressive disorder, and while ketamine offers rapid relief, its antidepressant effects fade within a few weeks.

30 Mar 2026

Nuclera launches GPCR-focused nanodisc panel to streamline membrane protein production

Nuclera, the biotechnology company enabling rapid access to high-quality proteins, today announced the launch of its nanodisc panel to support screening and scale-up of G-Protein Coupled Receptors (GPCRs).

From Nuclera 30 Mar 2026

Catheter-based approach improves prognosis in pulmonary embolism patients

Patients who had low doses of clot-buster drugs delivered directly to the site of a pulmonary embolism (PE) via a catheter using ultrasound to enhance their effect had significantly better outcomes than those who received standard systemic anticoagulants, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.26).

28 Mar 2026

New method reveals hidden protein motions for improved drug design

For many of us "protein" is the key element of a food order. However, beyond your preferred choice of meats or plant-based alternatives, proteins encompass a large class of complex biomolecules whose chemical structure is encoded in our genes.

27 Mar 2026

New neural organoid system improves scalability and reproducibility for research

Neural organoids have been heralded as having huge potential for advancing our knowledge of the brain in several fields.

27 Mar 2026

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Drugs News and Research

New dual drugs eliminate tumors when combined with immunotherapy

NIH funds AI project to advance Alzheimer’s research and treatment

New brain circuit discovery offers hope for chronic pain treatment

Small molecule may block protein buildup in neurodegenerative diseases

Popular vitamin B3 supplements could weaken cancer therapy effectiveness

Highly potent opioid shows potential as therapy for pain and opioid use disorder

Molecular switch in neurons found to limit the regrowth of damaged axonal fibers

"Smart" system distinguishes and neutralizes cancer cells with unprecedented precision

Trump’s one big beautiful bill act darkens outlook for government-backed clinics

Large study links more siblings to better bereavement coping

Purdue University accelerates rare disease drug discovery with the WELLJET dispenser stacker

Study reveals how extracellular matrix stiffness regulates breast cancer metastasis

Novel compound clears harmful protein, protects neurons in frontotemporal dementia models

Digoxin found safe to use in young patients with rheumatic heart disease

CFHR1 could be a new diagnostic marker for IgA nephropathy

NOX-1 identified as key molecular target to prolong ketamine's antidepressant effects

Nuclera launches GPCR-focused nanodisc panel to streamline membrane protein production

Catheter-based approach improves prognosis in pulmonary embolism patients

New method reveals hidden protein motions for improved drug design

New neural organoid system improves scalability and reproducibility for research

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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