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Study: Deceased-donor kidney transplants do not benefit all patients equally

A major international study, being presented today at the 62nd ERA Congress, reveals that the long-accepted survival advantage of deceased-donor kidney transplantation does not extend equally to every patient and every donor organ.

5 Jun 2025

Nicotinamide riboside shows promise in treating Werner syndrome symptoms

Werner syndrome (WS) is a rare genetic disorder that causes premature aging and serious complications. In the first clinical trial of its kind, researchers from Japan with the company Niagen Bioscience, investigated the effects of nicotinamide riboside (NR), a vitamin B3 derivative, in patients with WS.

5 Jun 2025

New data shows zigakibart sustains proteinuria remission and kidney function in IgA nephropathy

New 100-week data from the ongoing Phase 1/2 study of zigakibart, an investigational anti-APRIL monoclonal antibody, reinforce its potential as a disease-modifying treatment for IgA nephropathy (IgAN).

5 Jun 2025

New technique improve success rates in treating strokes and other clot-related diseases

When treating an ischemic stroke – where a clot is blocking the flow of oxygen to the brain – every minute counts.

4 Jun 2025

New marker identifies the functional maturity and heterogeneity of stem cell–derived islet organoids

Over 500 million people worldwide suffer from diabetes-a disease that contributes to major complications such as stroke, kidney failure, cancer, and Alzheimer's disease.

4 Jun 2025

Does lithium offer hope for long COVID brain fog and fatigue? New trial gives mixed results

A randomized clinical trial found that low-dose lithium aspartate did not improve cognitive dysfunction or fatigue in long COVID patients. Higher doses showed possible benefits in a small exploratory substudy, but larger trials are needed.

4 Jun 2025

Understanding why older Americans switch Medicare Advantage plans

More than half of older Americans now get their Medicare coverage through an insurance company's Medicare Advantage plan.

3 Jun 2025

New genetically modified fruit fly model sheds light on cocaine addiction

For the first time, researchers have created genetically modified fruit flies that can become addicted to cocaine.

2 Jun 2025

New microfluidic device brings affordable kidney testing to the point of care

Chronic kidney disease (CKD) affects over 800 million people globally and is often diagnosed too late for effective intervention.

31 May 2025

Study could change the definition of wound closure in diabetes care

In patients with diabetic foot ulcers that looked healed and met the current definition of a closed wound, closed ulcers with functionally defective skin that lost more body water were likely to re-open, according to a new National Institutes of Health (NIH) Diabetic Foot Consortium study, led by researchers at the University of Pittsburgh and published today in Diabetes Care.

31 May 2025

Study identifies diagnostic aid to accurately predict the recurrence of diabetic foot ulcers

NIH-funded project shows that trans-epidermal water loss could indicate if wounds are fully healed.

30 May 2025

Necrosis may hold the key to unlocking longevity and space health solutions

The process of necrosis, a form of cell death, may represent one of the most promising ways to change the course of human aging, disease and even space travel, according to a new study from researchers at UCL, drug discovery company LinkGevity and the European Space Agency (ESA).

29 May 2025

Wilms tumor found to contain millions of genetic changes

Researchers have uncovered that some childhood cancers have a substantially higher number of DNA changes than previously thought, changing the way we view children's tumours and possibly opening up new or repurposed treatment options.

29 May 2025

Sodium intake varies across racial and ethnic groups in the U.S.

Almost all adults in the U.S. consume more sodium (salt) than recommended, yet the sources and use of sodium vary among people of different races and ethnicities, indicating the need for culturally customized advice about sodium intake, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

28 May 2025

Silence on E. coli outbreak highlights how Trump team’s changes undermine food safety

Colton George felt sick. The 9-year-old Indiana boy told his parents his stomach hurt. He kept running to the bathroom and felt too ill to finish a basketball game.

28 May 2025

Delays in cancer diagnosis persist for young people with certain tumors

A new study, led by experts at the University of Nottingham, has found that young people suffering from certain types of cancer, such as bone tumors, are experiencing lengthy times to diagnosis.

27 May 2025

Maestro John Mauceri returns to the stage in renewed health

John Mauceri, an award-winning music conductor, author, and recording artist, is celebrating his return to the stage in better health following specialized cardiac surgery at NYU Langone Health to treat a rare and life-threatening heart condition.

27 May 2025

New biomarker identified for predicting microvascular health of the kidneys

In a world first, Canadian scientists at the CRCHUM, the hospital research centre affiliated with Université de Montréal, have identified microRNA able to protect small blood vessels and support kidney function after severe injury.

27 May 2025

Researchers find way to protect mitochondria from stress-induced damage

Mitochondria are the cell's power plants: They turn the food we eat into the energy our cells can use. But when stress hijacks the process they use to maintain their quality, they get snipped into useless fragments and go into a tailspin that spreads from cell to cell and triggers a wide range of human diseases.

26 May 2025

Aldosterone synthase inhibitor offers hope for treatment of uncontrolled hypertension

Lorundrostat, a novel therapy which blocks the production of aldosterone from the adrenal glands, demonstrated clinically meaningful and sustained reductions in blood pressure in 1,083 patients with uncontrolled or resistant hypertension, according to the results of a phase 3 trial announced today.

24 May 2025