Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Highly targeted gene therapy could revolutionize treatment for cancers linked to herpesvirus

In a preclinical study, UC Davis Comprehensive Cancer Center scientists developed a highly targeted gene therapy that could revolutionize treatment for cancers linked to a common herpesvirus, with minimal side effects.

2 Oct 2025

Early trial finds promise for avelumab and radiation in treating leptomeningeal disease

Researchers at Moffitt Cancer Center have reported encouraging results from a phase 1B clinical trial showing that the immunotherapy drug avelumab, when combined with whole brain radiotherapy, may provide a safe and effective treatment option for patients with leptomeningeal disease, one of the most aggressive and difficult-to-treat complications of advanced cancer.

30 Sep 2025

Proton therapy dose escalation may improve outcomes for glioblastoma patients

Previously, results from the photon cohort of the NRG-BN001, a signal seeking Phase II randomized trial, indicated that photon radiation dose intensification (75 Gy) did not demonstrate improvement in overall survival (OS) for patients with newly diagnosed glioblastoma (GBM).

30 Sep 2025

Digital tools and chatbots can expand genetic counseling for young cancer survivors

A groundbreaking new study from the Alliance for Clinical Trials in Oncology aims to test whether digital tools and chatbot technology can help young adult cancer survivors get the genetic counseling they need to better understand future health risks to themselves and family members.

30 Sep 2025

Stereotactic radiotherapy offers long-term survival outcomes comparable to surgery for NSCLC patients

A new clinical trial report finds that stereotactic radiation therapy offers long-term survival outcomes comparable to surgery for patients with small, early-stage non-small cell lung cancer (NSCLC). Patients in the study who received radiation also reported fewer side effects after treatment.

30 Sep 2025

Proton therapy offers no significant QOL advantage over photon therapy for breast cancer

The first randomized trial to compare photon- and proton-based radiation therapy for breast cancer finds that patients report equally strong health-related quality of life with either treatment. Patients who received proton therapy were more likely to say they would recommend or choose it again, but overall patient-reported outcomes were similar.

30 Sep 2025

Radiation therapy shows promise as safer alternative for severe heart rhythm disorder

Radiation therapy may offer a comparable and potentially safer alternative to repeat catheter ablation for patients with severe abnormal heart rhythms that can no longer be controlled with medication.

29 Sep 2025

Five-session SBRT reduces side effects in intermediate-risk prostate cancer

For patients with intermediate-risk, localized prostate cancer, radiation therapy delivered in five sessions reduced patient-reported side effects compared to longer courses of radiation, according to results of a large, randomized phase III trial.

29 Sep 2025

Post-operative radiation therapy reduces pelvic relapse in high-risk bladder cancer

Radiation therapy could be an underused tool to reduce pelvic relapse risk for patients with locally advanced, muscle-invasive bladder cancer, according to results of a new phase III randomized trial.

29 Sep 2025

Proton therapy and IMRT show similar outcomes in head and neck cancer trial

A new phase III clinical trial finds that intensity-modulated radiation therapy (IMRT) and proton beam therapy resulted in similar quality-of-life outcomes and low rates of side effects for people with locally advanced oropharyngeal cancer.

29 Sep 2025

Gene expression test identifies prostate cancer patients who benefit from hormone therapy

A new randomized study finds that a lab test that reads tumor genes can identify which patients with recurrent prostate cancer will benefit from adding hormone therapy to radiation after surgery - the first predictive biomarker in this setting.

29 Sep 2025

Combining radiopharmaceuticals with targeted radiation improves progression-free survival in prostate cancer patients

A new clinical trial finds that people with a limited number of metastases from recurrent prostate cancer lived significantly longer without disease progression when they received a radiopharmaceutical drug before targeted radiation, compared with radiation alone.

29 Sep 2025

Low-dose radiation therapy may be a suitable option for people with painful knee osteoarthritis

A single course of low-dose radiation therapy may provide a safe and effective alternative treatment option for people with painful knee osteoarthritis according to a new randomized, placebo-controlled clinical trial.

29 Sep 2025

AI tool accurately distinguishes between glioblastoma and primary central nervous system lymphoma

A Harvard Medical School–led research team has developed an AI tool that can reliably tell apart two look-alike cancers found in the brain but with different origins, behaviors, and treatments.

29 Sep 2025

Cancer cell nuclear hypertrophy can suppress metastasis

In tissue biopsies, cancer cells are frequently observed to have nuclei (the cell's genetic information storage) larger than normal.

29 Sep 2025

Can roselle help fight inflammation? New review suggests strong potential

A new review highlights the anti-inflammatory potential of Hibiscus sabdariffa (roselle), synthesizing evidence from 25 studies published between 2019 and 2024. Most findings are from preclinical models, but they point to promising roles in cardiovascular, metabolic, neuroprotective, and anticancer health.

28 Sep 2025

UCLA presents advances in radiation therapy at ASTRO 2025

Physicians and scientists from the UCLA Health Jonsson Comprehensive Cancer Center will share the latest research and clinical trial results at the 2025 American Society for Radiation Oncology (ASTRO) Annual Meeting, including studies on targeted radioactive therapy for recurrent prostate cancer, new approaches to stereotactic body radiation for prostate and head and neck cancers, advances in MRI- and 5DCT-guided imaging for more precise treatments, and innovations in patient-focused cancer education.

26 Sep 2025

Stereotactic body radiation therapy and surgery show similar outcomes for early lung cancer

Researchers from The University of Texas MD Anderson Cancer Center will present new data at the American Society for Radiation Oncology (ASTRO) 2025 Annual Meeting demonstrating that stereotactic body radiation therapy (SBRT) and surgery achieved similar survival outcomes at 10-year follow-up for patients with early-stage non-small cell lung cancer, with radiation offering quality-of-life benefits.

26 Sep 2025

Genetic testing guides personalized radiation patients with HPV-positive throat cancer

Genetic testing can identify patients with HPV-positive throat cancer who may benefit from lower radiation doses, according to Cleveland Clinic research.

26 Sep 2025

Novel treatment disrupts tumor immunosuppression in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with a five-year survival rate below 10%.

26 Sep 2025

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Oncology News and Research

Further Reading

Highly targeted gene therapy could revolutionize treatment for cancers linked to herpesvirus

Early trial finds promise for avelumab and radiation in treating leptomeningeal disease

Proton therapy dose escalation may improve outcomes for glioblastoma patients

Digital tools and chatbots can expand genetic counseling for young cancer survivors

Stereotactic radiotherapy offers long-term survival outcomes comparable to surgery for NSCLC patients

Proton therapy offers no significant QOL advantage over photon therapy for breast cancer

Radiation therapy shows promise as safer alternative for severe heart rhythm disorder

Five-session SBRT reduces side effects in intermediate-risk prostate cancer

Post-operative radiation therapy reduces pelvic relapse in high-risk bladder cancer

Proton therapy and IMRT show similar outcomes in head and neck cancer trial

Gene expression test identifies prostate cancer patients who benefit from hormone therapy

Combining radiopharmaceuticals with targeted radiation improves progression-free survival in prostate cancer patients

Low-dose radiation therapy may be a suitable option for people with painful knee osteoarthritis

AI tool accurately distinguishes between glioblastoma and primary central nervous system lymphoma

Cancer cell nuclear hypertrophy can suppress metastasis

Can roselle help fight inflammation? New review suggests strong potential

UCLA presents advances in radiation therapy at ASTRO 2025

Stereotactic body radiation therapy and surgery show similar outcomes for early lung cancer

Genetic testing guides personalized radiation patients with HPV-positive throat cancer

Novel treatment disrupts tumor immunosuppression in pancreatic cancer

Event guide: The 9th DDR Inhibitors Summit 2026 eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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