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Peptide-enhanced antibody therapy may help treat breast cancer metastasis to bone

A moderate amount of a peptide-enhanced, biological cancer drug goes a long way in treating breast cancers that metastasize to the bone.

24 Jan 2022

Study finds stable T-Cell response against Omicron after mRNA booster vaccination

A new study measured T cell activity in vaccinated individuals and found a third vaccine provided substantial T-cell immunity against the Omicron variant of SARS-CoV-2.

24 Jan 2022

An algorithm to predict host cleavage targets of SARS-CoV-2 3CLPro

In a recent study posted to the bioRxiv* preprint server, researchers developed a novel bioinformatic algorithm to predict host cleavage targets of the SARS-CoV-2 3C-like protease (3CLPro).

23 Jan 2022

Rapid, highly accurate drug detection vital to reducing the adverse impacts of addiction

Rapid, accessible and highly accurate detection of addictive substances such as opiates and cocaine is vital to reducing the adverse personal and societal impacts of addiction, something current drug detection systems can take too long to provide.

22 Jan 2022

Discovery illuminates a blueprint to develop new antibiotics for killing bacteria

The Centers for Disease Control and Prevention estimates that more than 2.8 million Americans experience antibiotic-resistant infections each year; more than 35,000 die from those infections.

20 Jan 2022

Researchers explore furin inhibitors as a potential tool for treating COVID-19 infection

A new study suggests that coronaviruses such as SARS-CoV-2 depend on a furin cleavage site between the S1/S2 subunits to enhance viral infectivity.

20 Jan 2022

Study finds COVID booster maintains strong T cell response against Omicron

New study results posted to the medRxiv* preprint server found that COVID vaccine boosters increase immunity by enhancing T cell immune memory. In the face of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) Omicron variant, vaccinated people who had received a third booster shot maintained high T cell responses than people with naturally acquired immunity or vaccine-induced immunity from two doses of the SARS‑CoV‑2 vaccine.

18 Jan 2022

Immune responses in Omicron breakthrough COVID-19

A recent study examined the question as to whether vaccination protects against Omicron infection by assessing breakthrough infection rates in participants at a superspreader event.

18 Jan 2022

Insignificant homology of SARS-CoV-2 spike sequences to myocarditis-associated antigens

Researchers determine whether sequences within SARS-CoV-2 could lead to an immune response to autoantigens associated with autoimmune myocarditis.

13 Jan 2022

Assessing how autoantibodies in COVID-19 correlate with anti-viral humoral responses

Researchers screen several systemic autoantibodies to assess their association with the severity of COVID-19.

13 Jan 2022

The unique T cell response elicited by SARS-CoV-2 during a primary immune response by infection and vaccination

The distinctive characteristics of the T cell response generated by SARS-CoV-2 infection and vaccination and the relationship to CCCoVs and VOC was explored in a review published in Frontiers in Medicine.

13 Jan 2022

Lack of evidence cross-reactive adaptive immune response is mechanism underlying COVID vaccine-induced myocarditis

Recently, the researchers from the USA, in their study published in the journal EBioMedicine, have conducted a sequence identity comparison and 3D protein structure comparison between the SARS-CoV-2 spike protein-derived peptides/protein and myocarditis-associated antigens and have found no significant enrichment in the frequency of spike-derived peptides similar to myocarditis-associated antigens that could have resulted in adaptive autoimmune responses leading to myocarditis.

12 Jan 2022

Adding a tomato concentrate to the diet can reduce intestinal inflammation related to HIV

New UCLA-led research in mice suggests that adding a certain type of tomato concentrate to the diet can reduce the intestinal inflammation that is associated with HIV. Left untreated, intestinal inflammation can accelerate arterial disease, which in turn can lead to heart attack and stroke.

11 Jan 2022

Developing a 'fingerprint' test that could diagnose Alzheimer’s early

In this interview, we spoke to Dr. Cynthia McMurray about her latest research into Alzheimer's disease.

11 Jan 2022

NeoCura and PhoreMost Announce Research Collaboration to Explore Novel Cancer Therapeutics

NeoCura and PhoreMost today announced an oncology drug discovery research collaboration.

From PhoreMost 11 Jan 2022

Mapping peripheral blood glycoprotein profiles of COVID-19 patients

A team of researchers recently analyzed differential protein glyco-isoform distributions of symptomatic and asymptomatic coronavirus disease 2019 patients.

11 Jan 2022

SARS-CoV-2 Delta binds more strongly to furin protease than other existing variants

Researchers conducted a computational analysis of the furin cleavage domain (FCD) of SARS-CoV-2 and its variants, as well as several other viruses.

10 Jan 2022

SARS-CoV-2 viral mutations shown to have a limited effect on T cell immunity

New research suggests that viral mutations have a minimal effect on T cell immunity, which could explain the protection provided by vaccination against severe COVID-19, despite the significant loss of neutralizing antibodies.

10 Jan 2022

SARS-CoV-2 Omicron a product of offensive evolution with compromised antigenicity

Researchers investigate the relationship between the SARS-CoV-2 Omicron variant and immune system based on self/nonself short constituent sequences.

9 Jan 2022

Study provides deeper insights into familial Alzheimer's disease pathogenesis

Alzheimer's disease (AD) is a progressive neurological disease that causes impairments in memory and cognition. AD is believed to result from the deposition of protein "plaques" consisting of amyloid beta (Aβ) proteins sequentially generated via the enzyme γ-secretase.

7 Jan 2022

Peptides News and Research

Peptide-enhanced antibody therapy may help treat breast cancer metastasis to bone

Study finds stable T-Cell response against Omicron after mRNA booster vaccination

An algorithm to predict host cleavage targets of SARS-CoV-2 3CLPro

Rapid, highly accurate drug detection vital to reducing the adverse impacts of addiction

Discovery illuminates a blueprint to develop new antibiotics for killing bacteria

Researchers explore furin inhibitors as a potential tool for treating COVID-19 infection

Study finds COVID booster maintains strong T cell response against Omicron

Immune responses in Omicron breakthrough COVID-19

Insignificant homology of SARS-CoV-2 spike sequences to myocarditis-associated antigens

Assessing how autoantibodies in COVID-19 correlate with anti-viral humoral responses

The unique T cell response elicited by SARS-CoV-2 during a primary immune response by infection and vaccination

Lack of evidence cross-reactive adaptive immune response is mechanism underlying COVID vaccine-induced myocarditis

Adding a tomato concentrate to the diet can reduce intestinal inflammation related to HIV

Developing a 'fingerprint' test that could diagnose Alzheimer’s early

NeoCura and PhoreMost Announce Research Collaboration to Explore Novel Cancer Therapeutics

Mapping peripheral blood glycoprotein profiles of COVID-19 patients

SARS-CoV-2 Delta binds more strongly to furin protease than other existing variants

SARS-CoV-2 viral mutations shown to have a limited effect on T cell immunity

SARS-CoV-2 Omicron a product of offensive evolution with compromised antigenicity

Study provides deeper insights into familial Alzheimer's disease pathogenesis

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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